erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weber FH et al. | Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. | 1993 | Am. J. Gastroenterol. | pmid:8470625 |
| Magat AH et al. | Double-blind randomized study comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. | 1993 | Obstet Gynecol | pmid:8469466 |
| Sabbah A | [Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha]. | 1993 | Allerg Immunol (Paris) | pmid:8466639 |
| Vasquez EM et al. | Clinically significant hearing loss in renal allograft recipients treated with intravenous erythromycin. | 1993 | Arch. Intern. Med. | pmid:8466379 |
| Hahn D | Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. | 1993 | Am. Rev. Respir. Dis. | pmid:8466109 |
| Driscoll MS et al. | Long-term oral antibiotics for acne: is laboratory monitoring necessary? | 1993 | J. Am. Acad. Dermatol. | pmid:8463461 |
| Mantzoros C et al. | Skin lesion in an acutely ill man with HIV. | 1993 | Hosp. Pract. (Off. Ed.) | pmid:8463358 |
| Eady EA et al. | Distribution of genes encoding erythromycin ribosomal methylases and an erythromycin efflux pump in epidemiologically distinct groups of staphylococci. | 1993 | J. Antimicrob. Chemother. | pmid:8463168 |
| Fiorucci S and Morelli A | Motilin and erythromycin stimulate pepsinogen secretion by chief cells isolated from guinea pig stomach. | 1993 | Gastroenterology | pmid:8462791 |
| Hoogeterp JJ et al. | Activity of erythromycin and clindamycin in an experimental Staphylococcus aureus infection in normal and granulocytopenic mice. A comparative in vivo and in vitro study. | 1993 | Scand. J. Infect. Dis. | pmid:8460336 |
| Spach DH et al. | Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus. | 1993 | J. Clin. Microbiol. | pmid:8458964 |
| Clotet B et al. | Rhodococcus equi infection in HIV-infected patients. | 1993 | J. Acquir. Immune Defic. Syndr. | pmid:8455149 |
| Edelbroek MA et al. | Effects of erythromycin on gastric emptying, alcohol absorption and small intestinal transit in normal subjects. | 1993 | J. Nucl. Med. | pmid:8455074 |
| Olkkola KT et al. | A potentially hazardous interaction between erythromycin and midazolam. | 1993 | Clin. Pharmacol. Ther. | pmid:8453848 |
| Karlowsky J et al. | A review of commonly prescribed oral antibiotics in general dentistry. | 1993 | J Can Dent Assoc | pmid:8453530 |
| Peterson MC et al. | Prosthetic hip infection and bacteremia due to Campylobacter jejuni in a patient with AIDS. | 1993 | Clin. Infect. Dis. | pmid:8452956 |
| Lindstrom TD et al. | Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers. | 1993 | Antimicrob. Agents Chemother. | pmid:8452357 |
| Coonan K and Kaplan EL | Therapeutic implications of erythromycin resistance in group A streptococci. | 1993 | Pediatr. Infect. Dis. J. | pmid:8451111 |
| Echizen H et al. | A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8450476 |
| Kusano S et al. | [Effect of erythromycin on neutrophil adhesion molecules]. | 1993 | Kansenshogaku Zasshi | pmid:8450276 |
| Ogino J et al. | [Effect of erythromycin on anti staphylococcal activity and dye production of Pseudomonas aeruginosa isolated from clinical materials]. | 1993 | Kansenshogaku Zasshi | pmid:8450271 |
| Roberts GA et al. | 6-Deoxyerythronolide B synthase 3 from Saccharopolyspora erythraea: over-expression in Escherichia coli, purification and characterisation. | 1993 | Biochem. Soc. Trans. | pmid:8449313 |
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| Fietta A et al. | Bioactivity of flurithromycin and other macrolides against intracellular susceptible staphylococci. | 1993 | Chemotherapy | pmid:8444060 |
| Carol P et al. | Erythromycin and 5S rRNA binding properties of the spinach chloroplast ribosomal protein CL22. | 1993 | Nucleic Acids Res. | pmid:8441674 |
| Catnach SM et al. | Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. | 1993 | Aliment. Pharmacol. Ther. | pmid:8439638 |
| Bartkowski RR et al. | Sufentanil disposition. Is it affected by erythromycin administration? | 1993 | Anesthesiology | pmid:8439020 |
| Knottenbelt DC | Rhodococcus equi infection in foals: a report of an outbreak on a thoroughbred stud in Zimbabwe. | 1993 | Vet. Rec. | pmid:8438546 |
| Falck G | [Therapy of whooping cough. Treatment for the "privileged", what about the others?]. | 1993 | Lakartidningen | pmid:8437454 |
| Roos K et al. | Interfering alpha-streptococci as a protection against recurrent streptococcal tonsillitis in children. | 1993 | Int. J. Pediatr. Otorhinolaryngol. | pmid:8436458 |
| Marrie TJ | Mycoplasma pneumoniae pneumonia requiring hospitalization, with emphasis on infection in the elderly. | 1993 | Arch. Intern. Med. | pmid:8435028 |
| Sladek GG and Frame JN | Rhodococcus equi causing bacteremia in an adult with acute leukemia. | 1993 | South. Med. J. | pmid:8434305 |
| Stacher G et al. | Erythromycin effects on gastric emptying, antral motility and plasma motilin and pancreatic polypeptide concentrations in anorexia nervosa. | 1993 | Gut | pmid:8432466 |
| Maskin SL | Infectious scleritis after a diabetic foot ulcer. | 1993 | Am. J. Ophthalmol. | pmid:8430739 |
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| O'Brien JF et al. | Dexamethasone as adjuvant therapy for severe acute pharyngitis. | 1993 | Ann Emerg Med | pmid:8427434 |
| Noah PK et al. | Evaluation of oral erythromycin and local isoniazid instillation therapy in infants with Bacillus Calmette-Guérin lymphadenitis and abscesses. | 1993 | Pediatr. Infect. Dis. J. | pmid:8426771 |
| Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
| Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
| Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
| Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
| Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
| Kadota J et al. | A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. | 1993 | Am. Rev. Respir. Dis. | pmid:8420410 |
| Pauker SG and Kopelman RI | Weak reasoning: diagnosis by drug reaction. | 1993 | N. Engl. J. Med. | pmid:8419820 |
| Rello J et al. | A three-year study of severe community-acquired pneumonia with emphasis on outcome. | 1993 | Chest | pmid:8417885 |
| Stassi D et al. | Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. | 1993 | J. Bacteriol. | pmid:8416893 |
| Pecevski J et al. | The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice. | 1977 | Strahlentherapie | pmid:841613 |
| Arayne MS and Sultana N | Erythromycin-antacid interaction. | 1993 | Pharmazie | pmid:8415858 |
| Paradisi M et al. | Efficacy of topical erythromycin in treatment of perianal streptococcal dermatitis. | 1993 | Pediatr Dermatol | pmid:8415314 |
| Dan M and Feigl D | Erythromycin-associated hypotension. | 1993 | Pediatr. Infect. Dis. J. | pmid:8414782 |
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| Umeki S | Anti-inflammatory action of erythromycin. Its inhibitory effect on neutrophil NADPH oxidase activity. | 1993 | Chest | pmid:8404190 |
| Hughes J and Burrows NP | Infectious mononucleosis presenting as erythema multiforme. | 1993 | Clin. Exp. Dermatol. | pmid:8403481 |
| Rubart M et al. | Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome. | 1993 | Circulation | pmid:8403329 |
| Zapp ML et al. | Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production. | 1993 | Cell | pmid:8402886 |
| Navarro H et al. | Effect of erythromycin on D-galactose absorption and sucrase activity in rabbit jejunum. | 1993 Mar-Apr | Can. J. Physiol. Pharmacol. | pmid:8402381 |
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| Kenny GE and Cartwright FD | Effect of pH, inoculum size, and incubation time on the susceptibility of Ureaplasma urealyticum to erythromycin in vitro. | 1993 | Clin. Infect. Dis. | pmid:8399919 |
| Waites KB et al. | Therapeutic considerations for Ureaplasma urealyticum infections in neonates. | 1993 | Clin. Infect. Dis. | pmid:8399918 |
| Gallar P et al. | Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. | 1993 | Perit Dial Int | pmid:8399560 |
| Rumpianesi F et al. | In vitro activity of azithromycin against Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in comparison with erythromycin, roxithromycin and minocycline. | 1993 | J Chemother | pmid:8396626 |
| Weippl G | Multicentre comparison of azithromycin versus erythromycin in the treatment of paediatric pharyngitis or tonsillitis caused by group A streptococci. | 1993 | J. Antimicrob. Chemother. | pmid:8396103 |
| Hamill J | Multicentre evaluation of azithromycin and penicillin V in the treatment of acute streptococcal pharyngitis and tonsillitis in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396102 |
| Schaad UB | Multicentre evaluation of azithromycin in comparison with co-amoxiclav for the treatment of acute otitis media in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396101 |
| Mohs E et al. | A comparative study of azithromycin and amoxycillin in paediatric patients with acute otitis media. | 1993 | J. Antimicrob. Chemother. | pmid:8396100 |
| Daniel RR | Comparison of azithromycin and co-amoxiclav in the treatment of otitis media in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396099 |
| Mazzei T et al. | Pharmacokinetics of azithromycin in patients with impaired hepatic function. | 1993 | J. Antimicrob. Chemother. | pmid:8396098 |
| Wildfeuer A et al. | Comparison of the pharmacokinetics of three-day and five-day regimens of azithromycin in plasma and urine. | 1993 | J. Antimicrob. Chemother. | pmid:8396097 |
| Retsema JA et al. | Preferential concentration of azithromycin in an infected mouse thigh model. | 1993 | J. Antimicrob. Chemother. | pmid:8396096 |
| Foulds G and Johnson RB | Selection of dose regimens of azithromycin . | 1993 | J. Antimicrob. Chemother. | pmid:8396095 |
| Girard AE et al. | The comparative activity of azithromycin, macrolides and amoxycillin against streptococci in experimental infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396094 |
| Waugh MA | Open study of the safety and efficacy of a single oral dose of azithromycin for the treatment of uncomplicated gonorrhoea in men and women. | 1993 | J. Antimicrob. Chemother. | pmid:8396093 |
| Lister PJ et al. | Comparison of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in men. | 1993 | J. Antimicrob. Chemother. | pmid:8396092 |
| Lauharanta J et al. | Single-dose oral azithromycin versus seven-day doxycycline in the treatment of non-gonococcal urethritis in males. | 1993 | J. Antimicrob. Chemother. | pmid:8396091 |
| Fitzgeorge RB et al. | A comparison of the efficacy of azithromycin and clarithromycin in oral therapy of experimental airborne Legionnaires' disease. | 1993 | J. Antimicrob. Chemother. | pmid:8396090 |
| Girard D et al. | Comparison of azithromycin, roxithromycin, and cephalexin penetration kinetics in early and mature abscesses. | 1993 | J. Antimicrob. Chemother. | pmid:8396089 |
| Myburgh J et al. | The efficacy and tolerance of a three-day course of azithromycin in the treatment of community-acquired pneumonia. | 1993 | J. Antimicrob. Chemother. | pmid:8396088 |
| Bradbury F | Comparison of azithromycin versus clarithromycin in the treatment of patients with lower respiratory tract infection. | 1993 | J. Antimicrob. Chemother. | pmid:8396087 |
| Hoepelman AI et al. | A single-blind comparison of three-day azithromycin and ten-day co-amoxiclav treatment of acute lower respiratory tract infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396086 |
| Müller O | Comparison of azithromycin versus clarithromycin in the treatment of patients with upper respiratory tract infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396085 |
| Amaya-Tapia G et al. | Once-daily azithromycin in the treatment of adult skin and skin-structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396084 |
| Lo Bue AM et al. | Efficacy of azithromycin compared with spiramycin in the treatment of odontogenic infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396083 |
| Hopkins S | Clinical safety and tolerance of azithromycin in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396082 |
| Rodriguez-Solares A et al. | A comparative study of the efficacy, safety and tolerance of azithromycin, dicloxacillin and flucloxacillin in the treatment of children with acute skin and skin-structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396081 |
| Panteix G et al. | In-vitro concentration of azithromycin in human phagocytic cells. | 1993 | J. Antimicrob. Chemother. | pmid:8396080 |
| Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
| Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
| Wathne B et al. | Erythromycin versus metronidazole in the treatment of bacterial vaginosis. | 1993 | Acta Obstet Gynecol Scand | pmid:8394627 |
| Molinari G et al. | Inhibition of Pseudomonas aeruginosa virulence factors by subinhibitory concentrations of azithromycin and other macrolide antibiotics. | 1993 | J. Antimicrob. Chemother. | pmid:8392997 |