erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wang S et al. | Comparison of microbial communities in sequencing batch reactors (SBRs) exposed to trace erythromycin and erythromycin-Hâ‚‚O. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24072160 |
Liao D et al. | Quantitative differences between primary and secondary peristaltic contractions of the esophagus. | 2014 | Dig. Dis. Sci. | pmid:24682721 |
Luminos M et al. | Nasopharyngeal carriage of Streptococcus pneumoniae in Romanian children before the introduction of the pneumococcal conjugated vaccination into the national immunization programme: a national, multi-centre, cross-sectional observational study. | 2014 | Int. J. Infect. Dis. | pmid:25461243 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Ziupa D et al. | Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. | 2014 | PLoS ONE | pmid:25244401 |
Westerhof J et al. | Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. | 2014 | BMC Gastroenterol | pmid:25234278 |
Flamm RK et al. | Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. | 2014 | Antimicrob. Agents Chemother. | pmid:24514082 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Nuyujukian DS et al. | Medication use and multiple myeloma risk in Los Angeles County. | 2014 | Cancer Causes Control | pmid:24981100 |
Iatrou EI et al. | Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24981036 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Yosida M et al. | Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. | 2014 | Diabetes | pmid:24824430 |
Hellmann-Regen J et al. | Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? | 2014 | Exp. Dermatol. | pmid:24690039 |
Siira L et al. | Antimicrobial resistance in relation to sero- and genotypes among invasive Streptococcus pneumoniae in Finland, 2007-2011. | 2014 | Microb. Drug Resist. | pmid:24266666 |
Xu J et al. | Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. | 2014 | J. Food Sci. | pmid:24689704 |
Wang D et al. | Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. | 2014 | Microb. Drug Resist. | pmid:24684286 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Utsunomiya S et al. | Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. | 2013 | Regul. Pept. | pmid:23142315 |
Li YJ et al. | EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. | 2013 | Pulm Pharmacol Ther | pmid:23291319 |
Berghaus LJ et al. | Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. | 2013 | Vet. Microbiol. | pmid:23915992 |
Janssen P et al. | The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. | 2013 | Am. J. Gastroenterol. | pmid:24005344 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). | 2013 | J. Fish Dis. | pmid:24118016 |
Sripriya J et al. | Laser receptive polyelectrolyte thin films doped with biosynthesized silver nanoparticles for antibacterial coatings and drug delivery applications. | 2013 | Int J Pharm | pmid:24096301 |
Kelley C et al. | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. | 2013 | Eur J Med Chem | pmid:23314053 |
González-Pleiter M et al. | Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. | 2013 | Water Res. | pmid:23399078 |
Odhav A et al. | Subconjunctival latex paint from occupational injury. | 2013 | J Emerg Med | pmid:23399395 |
Chen Y et al. | Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. | 2013 | Bioresour. Technol. | pmid:23500575 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Basak R and Bandyopadhyay R | Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. | 2013 | Langmuir | pmid:23472840 |
Broad J and Sanger GJ | The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. | 2013 | Br. J. Pharmacol. | pmid:23190027 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
Yang J et al. | Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. | 2013 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:23474502 |
Chen Y et al. | Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. | 2013 | Bioprocess Biosyst Eng | pmid:23361182 |
Hinarejos P et al. | The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. | 2013 | J Bone Joint Surg Am | pmid:23636182 |
Roberts DW | What is the role of antibiotic-containing cement in total knee arthroplasty? | 2013 | J Bone Joint Surg Am | pmid:23636201 |
Sun W et al. | [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. | 2013 | Yao Xue Xue Bao | pmid:23672013 |
Wang H et al. | High prevalence of fluoroquinolone-resistant group B streptococci among clinical isolates in China and predominance of sequence type 19 with serotype III. | 2013 | Antimicrob. Agents Chemother. | pmid:23295933 |
Pelchovich G et al. | Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene. | 2013 | Int. J. Antimicrob. Agents | pmid:23664678 |
Marcellin E et al. | Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. | 2013 | BMC Genomics | pmid:23324121 |
Romeiro FG et al. | Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study. | 2013 | BMC Gastroenterol | pmid:23324408 |
Elens L et al. | Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin. | 2013 | Pharmacogenet. Genomics | pmid:23324807 |
Gómez-Sanz E et al. | Analysis of a novel erm(T)- and cadDX-carrying plasmid from methicillin-susceptible Staphylococcus aureus ST398-t571 of human origin. | 2013 | J. Antimicrob. Chemother. | pmid:23075692 |