erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Appelbaum PC et al. | Carriage of antibiotic-resistant Streptococcus pneumoniae by children in eastern and central Europe--a multicenter study with use of standardized methods. | 1996 | Clin. Infect. Dis. | pmid:8909832 |
Nakagawa M et al. | Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis. | 1996 | J. Neurovirol. | pmid:8912211 |
Hayakawa H et al. | Bronchiolar disease in rheumatoid arthritis. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8912776 |
Sutcliffe J et al. | Detection of erythromycin-resistant determinants by PCR. | 1996 | Antimicrob. Agents Chemother. | pmid:8913465 |
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Kleinman B | Should antibiotics be prophylactically administered to a patient with an asymptomatic systolic murmur? | 1996 | Anesthesiology | pmid:8916856 |
Bowles KM et al. | A 35-year-old with swollen knees who had recurrent fever and pericarditis, then diarrhoea before getting better. | 1996 | Lancet | pmid:8918280 |
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Regnery RL et al. | Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. | 1996 | Am. J. Vet. Res. | pmid:8950424 |
Ringger NC et al. | Effect of bethanechol or erythromycin on gastric emptying in horses. | 1996 | Am. J. Vet. Res. | pmid:8950433 |
Fass RJ et al. | The utility of non-beta-lactam antimicrobial MICs as markers to distinguish oxacillin-resistant from oxacillin-susceptible strains of Staphylococcus epidermidis. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8950529 |
Mittermayer H et al. | Antibiotic susceptibility of pneumococci isolated in Austria over a four-year period. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8950561 |
Kalliafas S et al. | Erythromycin facilitates postpyloric placement of nasoduodenal feeding tubes in intensive care unit patients: randomized, double-blinded, placebo-controlled trial. | 1996 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:8950737 |
Durak H et al. | Lung clearance of inhaled 99Tcm-erythromycin lactobionate in non-smokers and smokers. | 1996 | Nucl Med Commun | pmid:8951912 |
Roos K et al. | Recolonization with selected alpha-streptococci for prophylaxis of recurrent streptococcal pharyngotonsillitis--a randomized placebo-controlled multicentre study. | 1996 | Scand. J. Infect. Dis. | pmid:8953674 |
Suwabe A et al. | [Effects of erythromycin on surfactant synthesis, secretion, and recycling by rat alveolar type II cells]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8953904 |
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Yamazaki H et al. | Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes. | 1996 | J Toxicol Sci | pmid:8959645 |
Lagergård T et al. | Comparison of the Etest with agar dilution for antimicrobial susceptibility testing of Haemophilus ducreyi. | 1996 | J. Antimicrob. Chemother. | pmid:8961054 |
Antzelevitch C et al. | Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsade de pointes. | 1996 | J. Am. Coll. Cardiol. | pmid:8962574 |
Rahal JJ and Simberkoff MS | Cases 1, 2, and 3. | 1977 | Postgrad Med | pmid:896609 |
Grandjean C and Lukacs G | Preparation and in vitro antibacterial activity of 9-O-glycosyloxime derivatives of erythromycin A, a new class of macrolide antibiotics. | 1996 | J. Antibiot. | pmid:8968398 |
Lazarevski G et al. | Ring opening reactions of 6-deoxy-9-deoxo-9a-aza-9a-homoerythromycin A 6,9-cyclic imino ether. | 1996 | J. Antibiot. | pmid:8968405 |
Kimber RG | Treating acute bronchitis. | 1996 | J Fam Pract | pmid:8969686 |
Kaufman D | Treating acute bronchitis. | 1996 | J Fam Pract | pmid:8969687 |
Jorro G et al. | Anaphylaxis to erythromycin. | 1996 | Ann. Allergy Asthma Immunol. | pmid:8970433 |
Landry C et al. | Could oral erythromycin optimize high energy continuous enteral nutrition? | 1996 | Aliment. Pharmacol. Ther. | pmid:8971296 |
Jenkins IR and Gibson J | Cisapride, erythromycin and arrhythmia. | 1996 | Anaesth Intensive Care | pmid:8971331 |
Clancy J et al. | Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes. | 1996 | Mol. Microbiol. | pmid:8971709 |
van't Hullenaar NG et al. | Relapse of Legionella longbeachae infection in an immunocompromised patient. | 1996 | Neth J Med | pmid:8973096 |
Kakkos SK et al. | Gallbladder contraction induced by intravenous erythromycin administration. Relation to body mass index. | 1996 Nov-Dec | Hepatogastroenterology | pmid:8975963 |
Mashimoto H et al. | [Acute bronchiolitis due to Mycoplasma pneumoniae and successfully treated with steroids]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8976087 |
Moriyasu H et al. | [Erythromycin-induced hearing loss in a patient with Listeria monocytogenes meningo-ventriculitis]. | 1996 | Rinsho Shinkeigaku | pmid:8976138 |
Adachi T et al. | Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. | 1996 | J. Allergy Clin. Immunol. | pmid:8977529 |
Brugiere O et al. | Diffuse panbronchiolitis in an Asian immigrant. | 1996 | Thorax | pmid:8977613 |
Neri I et al. | Perianal streptococcal dermatitis in adults. | 1996 | Br. J. Dermatol. | pmid:8977685 |
Watkins VS et al. | Comparison of dirithromycin and penicillin for treatment of streptococcal pharyngitis. | 1997 | Antimicrob. Agents Chemother. | pmid:8980757 |
Fasola EL et al. | Variation in erythromycin and clindamycin susceptibilities of Streptococcus pneumoniae by four test methods. | 1997 | Antimicrob. Agents Chemother. | pmid:8980768 |
Vermeij CG et al. | Campylobacter jejuni peritonitis in a patient with liver cirrhosis. | 1996 | Eur J Gastroenterol Hepatol | pmid:8980944 |
Brenciaglia MI et al. | Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. | 1996 | J Chemother | pmid:8981182 |
Sasaki J et al. | Microbial glycosylation of macrolide antibiotics by Streptomyces hygroscopicus ATCC 31080 and distribution of a macrolide glycosyl transferase in several Streptomyces strains. | 1996 | J. Antibiot. | pmid:8982340 |
Ono T et al. | In vitro and in vivo antibacterial activities of clarithromycin. | 1996 May-Jun | Chemotherapy | pmid:8983882 |
Shortridge VD et al. | Novel mechanism of macrolide resistance in Streptococcus pneumoniae. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8985659 |
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). I. A Pilot study of the new vitamin C infusion treatment with a volunteer CFS patient. | 1996 Nov-Dec | In Vivo | pmid:8986467 |
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). II. Characterization of CFS patients with special reference to their response to a new vitamin C infusion treatment. | 1996 Nov-Dec | In Vivo | pmid:8986468 |
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Johnson DM and Jones RN | Two investigational glycylcyclines, DMG-DMDOT and DMG-MINO. Antimicrobial activity studies against gram-positive species. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8988765 |
Lakritz J et al. | Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals. | 1997 | Am. J. Vet. Res. | pmid:8989497 |
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Kane GC | Legionella species community-acquired pneumonia. | 1997 | Chest | pmid:8996030 |
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Yamada K et al. | Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. | 1996 | Am. J. Physiol. | pmid:8997244 |
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Goldberg MJ et al. | Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo. | 1996 | J Clin Pharmacol | pmid:9013373 |
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Moutard I et al. | In vitro interaction between dirithromycin or its metabolite, erythromycylamine, and oxidative polymorphonuclear metabolism. | 1997 | J. Antibiot. | pmid:9066766 |
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