erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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TIBOLDI T et al. | EXPERIENCE WITH SELYE'S GRANULOMA POUCH TECHNIQUE. | 1964 | Acta Physiol Acad Sci Hung | pmid:14196571 |
Zhang L et al. | P-glycoprotein restricted transport of nimodipine across blood-brain barrier. | 2003 | Acta Pharmacol. Sin. | pmid:12956939 |
Kaltiala EH et al. | Subchronic toxicity of some erythromycin compounds in rats. | 1967 | Acta Pharmacol Toxicol (Copenh) | pmid:5630681 |
RASMUSSEN F | Mammary excretion of benzylpenicillin, erythromycin, and penethamate hydroiodide. | 1959 | Acta Pharmacol Toxicol (Copenh) | pmid:14436357 |
Berntsson P | The use of non-correlated log P and (log P) 2 values in quantitative structure activity relationships. | 1980 | Acta Pharm. Suec. | pmid:7468238 |
Manna PK et al. | Preparation and evaluation of a new erythromycin derivative -- erythromycin taurate. | 2004 | Acta Pharm | pmid:15610619 |
Dornbusch K and Dahlström A | A genetic study of inducible erythromycin resistance in Staphylococcus aureus. | 1973 | Acta Pathol Microbiol Scand B Microbiol Immunol | pmid:4275707 |
Thomsen M | The Burns Unit in Copenhagen. 11. Phage types of Staphylococcus aureus and the relation to antibiotic sensitivity. | 1971 | Acta Pathol Microbiol Scand B Microbiol Immunol | pmid:4253900 |
Engbaek HC et al. | Non-photochromogenic mycobacteria serotype Davis. The inhomogeneity within the serological group and the relationship to Mycobacterium avium. | 1970 | Acta Pathol Microbiol Scand B Microbiol Immunol | pmid:4322001 |
Casals JB and Pedersen OG | Tablet sensitivity testing: a comparison of different methods. | 1972 | Acta Pathol Microbiol Scand B Microbiol Immunol | pmid:4345659 |