erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Christensen JJ et al. | Chlamydia trachomatis: in vitro susceptibility to antibiotics singly and in combination. | 1986 | Acta Pathol Microbiol Immunol Scand B | pmid:3788573 |
Jansen JE and Bremmelgaard A | Susceptibility testing of 7 antibiotics against anaerobic bacteria: comparison of 2 different media and carbon dioxide concentrations. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3105247 |
Andreasen JJ et al. | Influence of carbon-dioxide tension and medium buffer concentration on medium pH and MIC values of erythromycin for Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923 in a micro-aerobic atmosphere. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3118638 |
Frimodt-Møller N and Thomsen VF | The pneumococcus and the mouse-protection test: correlation of in vitro and in vivo activity for beta-lactam antibiotics, vancomycin, erythromycin and gentamicin. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3630711 |
Dibb WL et al. | Effects of carbon dioxide upon the in vitro activity of erythromycin. | 1986 | Acta Pathol Microbiol Immunol Scand B | pmid:3090858 |
Burova LA et al. | The genetic control of virulence in group A streptococci. II. Trigger effect by plasmids on anti-phagocytic activity, opacity factor and IgG and IgA Fc-receptors. | 1983 | Acta Pathol Microbiol Immunol Scand B | pmid:6346793 |
Ravdonikas LE et al. | The genetic control of virulence in group A streptococci. III. Plasmid-induced "switch-off"--effect on some pathogenic properties. | 1984 | Acta Pathol Microbiol Immunol Scand B | pmid:6369874 |
Digranes A et al. | Coumermycin: in vitro activity against 251 clinical isolates of bacteria compared with the activities of eight other antibacterial agents. | 1986 | Acta Pathol Microbiol Immunol Scand B | pmid:3728027 |
Bhattacharya MK et al. | Azithromycin in the treatment of cholera in children. | 2003 | Acta Paediatr. | pmid:12856976 |
Manteau C et al. | Acute severe spinal cord dysfunction in a child with meningitis: Streptococcus pneumoniae and Mycoplasma pneumoniae co-infection. | 2005 | Acta Paediatr. | pmid:16279003 |