erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Choroiditis D002833 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Sialadenitis D012793 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Microphthalmos D008850 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Epidural Abscess D020802 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Angiomatosis D000798 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Myiasis D009198 1 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Ehrlichiosis D016873 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Gardner Syndrome D005736 2 associated lipids
Bile Reflux D001655 2 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Rubella D012409 2 associated lipids
Seroma D049291 2 associated lipids
Furunculosis D005667 2 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Hypoventilation D007040 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Sorensen EM and Acosta D Erythromycin estolate-induced toxicity in cultured rat hepatocytes. 1985 Toxicol. Lett. pmid:4060187
Saxena RP et al. Coir fibre toxicity: in vivo and in vitro studies. 1982 Toxicol. Lett. pmid:6283694
Mazur CS et al. P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. 2015 Toxicol. Lett. pmid:25268938
Montenez JP et al. Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. 1999 Toxicol. Appl. Pharmacol. pmid:10198278
Mahgoub A et al. Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. 2005 Toxicol. Appl. Pharmacol. pmid:15885263
Gracia T et al. Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds. 2007 Toxicol. Appl. Pharmacol. pmid:17822730
Gant TW et al. In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys. 1995 Toxicol. Appl. Pharmacol. pmid:7645023
Fujii E et al. Assessment of the carcinogenic potential of mitemcinal (GM-611): increased incidence of malignant lymphoma in a rat carcinogenicity study. 2008 Toxicol. Appl. Pharmacol. pmid:18355581
Dakhel Y and Jamali F Erythromycin potentiates PR interval prolonging effect of verapamil in the rat: a pharmacodynamic drug interaction. 2006 Toxicol. Appl. Pharmacol. pmid:16466760
Gray JE et al. Drug-induced enteropathy characterized by lipid in macrophages. 1974 Toxicol. Appl. Pharmacol. pmid:4136643
Gray JE et al. Ultrastructural studies of the hepatic changes brought about by Clindamycin and Erythromycin in animals. 1971 Toxicol. Appl. Pharmacol. pmid:4328315
Iwamoto HK and Brennan WR The effect of demeclocycline, methacycline, and erythromycin on tooth color in the rat. 1969 Toxicol. Appl. Pharmacol. pmid:4975609
Dujovne CA Liver cell culture toxicity and surfactant potency of erythromycin derivatives. 1975 Toxicol. Appl. Pharmacol. pmid:1135866
Sadrieh N and Thomas PE Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins. 1994 Toxicol. Appl. Pharmacol. pmid:8048065
WORTH HM et al. INTRAGASTRIC INJECTION FOR TOXICITY STUDIES WITH NEWBORN RATS. 1963 Toxicol. Appl. Pharmacol. pmid:14082477
Gray JE et al. Foam cell response in the lung and lymphatic tissues during long-term high-level treatment with erythromycin. 1978 Toxicol. Appl. Pharmacol. pmid:725925
Kalsotra A et al. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. 2004 Toxicol. Appl. Pharmacol. pmid:15364545
DeSalva SJ et al. Lethal effects of antibiotics in hamsters. 1969 Toxicol. Appl. Pharmacol. pmid:5787519
Gaeta GB et al. Characterization of the effects of erythromycin estolate and erythromycin base on the excretory function of the isolated rat liver. 1985 Toxicol. Appl. Pharmacol. pmid:2992120
Flaman AS et al. The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. 2011 Toxicol. Appl. Pharmacol. pmid:21466820
Hayashi S et al. Characterization of multinuclear hepatocytes induced in rats by mitemcinal (GM-611), an erythromycin derivative. 2008 Toxicol Pathol pmid:18776165
Abdel-Hameid NA Protective role of dimethyl diphenyl bicarboxylate (DDB) against erythromycin induced hepatotoxicity in male rats. 2007 Toxicol In Vitro pmid:17267170
Tilmant K et al. Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. 2011 Toxicol In Vitro pmid:21515356
Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
BARDIER A et al. [Results of infantile propiocine granulated for syrup in infections pathology in infants (Apropos of 71 cases)]. 1961 Toulouse Med pmid:13686911
BARDIER A et al. [CURRENT TREATMENT OF PLEURO-PULMONARY STAPHYLOCOCCAL INFECTIONS IN INFANTS (APROPOS OF 60 CASES)]. 1964 Toulouse Med pmid:14169371
DUBRA F [PATHOLOGY OF PULMONARY TUBERCULOSIS CAUSED BY RESISTANT BACTERIA]. 1963 Sep-Dec Torax pmid:14158172
DUBRA F [THE CURE OF PULMONARY TUBERCULOSIS CAUSED BY RESISTANT BACTERIA]. 1963 Sep-Dec Torax pmid:14158173
PALERMO FM [SECONDARY BACTERIAL RESISTANCE]. 1963 Sep-Dec Torax pmid:14159781
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
MUNOZBLAZQUEZ J [ANTIBIOTIC-CORTISONE TREATMENT OF GENITAL INFLAMMATION]. 1964 Tokoginecol Pract pmid:14108914
Hara T et al. Successful treatment of severe reflux esophagitis with erythromycin in a patient with progressive systemic sclerosis and proximal gastrectomy. 2006 Tokai J. Exp. Clin. Med. pmid:21302226
Partiarca PA et al. Outbreaks of pertussis in the United States: the Wisconsin experience. 1988 Tokai J. Exp. Clin. Med. pmid:3273611
Onodera T et al. Effect of fluid and antibiotic administration on experimental fecal peritonitis. 1968 Tohoku J. Exp. Med. pmid:5715596
Kanemitsu K et al. Efficacy of amikacin combinations for nocardiosis. 2003 Tohoku J. Exp. Med. pmid:14649737
Ramos CJ and Antonetti DA The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. 2017 Tissue Barriers pmid:28632993
van der Kuy A et al. [The erythromycin group]. 1974 Tijdschr Ziekenverpl pmid:4499128
van der Lely N et al. [A child with Chlamydia trachomatis pneumonia]. 1993 Tijdschr Kindergeneeskd pmid:8266317
Schurgers M et al. [A case of toxic hepatitis]. 1974 Tijdschr Gastroenterol pmid:4454054
Devriese L [Antibiotic sensitivity tests (author's transl)]. 1976 Tijdschr Diergeneeskd pmid:827819
Boswinkel M and Sloet van Oldruitenborgh-Oosterbaan MM [Diagnosis and therapy of Rhodococcus equi infection in the horse]. 2006 Tijdschr Diergeneeskd pmid:16989420
van der Toorn F and Lumeij JT [Streptococcus gallolyticus infections in racing pigeons, a literature review]. 2001 Tijdschr Diergeneeskd pmid:11227399
Høye S An extraordinary tale of an ordinary case. 2015 Tidsskr. Nor. Laegeforen. pmid:26130550
Ose L [Encephalitis associated with mycoplasma pneumoniae infection in children]. 1975 Tidsskr. Nor. Laegeforen. pmid:1145545
Lind O and Harthug S [Hearing loss after erythromycin therapy]. 1993 Tidsskr. Nor. Laegeforen. pmid:8211901
Brauteset LV et al. [Invasive pneumoccal disease in children in Oslo 1998-2004]. 2008 Tidsskr. Nor. Laegeforen. pmid:18552897
Volden G [Syphilis]. 1980 Tidsskr. Nor. Laegeforen. pmid:6992342
Lefsaker L et al. [Legionnaires' disease]. 1988 Tidsskr. Nor. Laegeforen. pmid:3353900
Hassel B [Acute hypothermia and adverse effects on the central nervous system during erythromycin therapy]. 1994 Tidsskr. Nor. Laegeforen. pmid:7915859
Afset JE and Maeland JA [Erythromycin and ciprofloxacin resistant Campylobacter jejuni]. 2001 Tidsskr. Nor. Laegeforen. pmid:11571989