erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stickney RH et al. | Chlamydia trachomatis: a cause of an infantile pneumonia syndrome. | 1978 | AJR Am J Roentgenol | pmid:101061 |
Simakova MG et al. | [Clinical aspects, diagnosis and treatment of intrauterine infections]. | 1995 | Akush Ginekol (Mosk) | pmid:7485765 |
Mezinova NN et al. | [Effect of anti-chlamydial drugs on the effectiveness of the treatment of habitual abortion]. | 1991 | Akush Ginekol (Mosk) | pmid:1951968 |
Mezinova NN and Chuchupalov PD | [Endometrial Chlamydia infection in women with habitual abortion]. | 1992 | Akush Ginekol (Mosk) | pmid:1476220 |
Kotua EN and Moroz AF | [Erythromycin-ascorbinate therapy of pregnant rats with staphylococcal infections caused by staphylococcal strains both sensitive and resistant to erythromycin]. | 1971 | Akush Ginekol (Mosk) | pmid:5138198 |
Kotua EN and Moroz AF | [Passage of erythromycin and ristomycin into blood, placenta, fetus and amniotic fluid during various stages of pregnancy in generalized staphylococcal infection in albino rats]. | 1971 | Akush Ginekol (Mosk) | pmid:4328638 |
Thornton JB and Harris JH | The prevention of bacterial endocarditis. A new approach to a changing disease. | 1986 | Ala J Med Sci | pmid:3953983 |
BOURICHON J | [Importance of the suppository form in the administration of propionyl-erythromycin to children]. | 1962 | Alger Medicale | pmid:13871918 |
LEBON J et al. | [Staphylococcal diarrhea after terramycin administration; cure by erythromycin]. | 1955 | Alger Medicale | pmid:14398597 |
Van Herwaarden MA et al. | The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:10759625 |
Russo A et al. | Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. | 2004 | Aliment. Pharmacol. Ther. | pmid:15274670 |
Bai Y et al. | Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. | 2011 | Aliment. Pharmacol. Ther. | pmid:21615438 |
Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
Emmanuel AV et al. | Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response. | 2004 | Aliment. Pharmacol. Ther. | pmid:15023171 |
Bell GD et al. | Short report: omeprazole plus antibiotic combinations for the eradication of metronidazole-resistant Helicobacter pylori. | 1992 | Aliment. Pharmacol. Ther. | pmid:1486161 |
Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |
Minocha A et al. | Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. | 1995 | Aliment. Pharmacol. Ther. | pmid:8580273 |
Osato MS et al. | Comparative efficacy of new investigational agents against Helicobacter pylori. | 2001 | Aliment. Pharmacol. Ther. | pmid:11284777 |
Medhus AW et al. | Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. | 2000 | Aliment. Pharmacol. Ther. | pmid:10651665 |
Kendall BJ et al. | The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146779 |