erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nakashima R et al. | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. | 2011 | Nature | pmid:22121023 |
Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
Werner CR et al. | [Unexpected complication following esophageal variceal hemorrhage - Case 2/2011]. | 2011 | Dtsch. Med. Wochenschr. | pmid:21271486 |
Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
Wright AJ et al. | The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. | 2011 | CMAJ | pmid:21242274 |
Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
Zhang L et al. | Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. | 2011 | J. Antibiot. | pmid:21245870 |
Nielsen EI et al. | Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. | 2011 | Antimicrob. Agents Chemother. | pmid:21282424 |
Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
Wunder DB et al. | Sorption of antibiotics to biofilm. | 2011 | Water Res. | pmid:21334040 |
Liu Y et al. | The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21570844 |
Samra Z et al. | Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin. | 2011 | J Chemother | pmid:21571622 |
Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
Bistrian BR | Enteral feeding: good, but not for everyone. | 2011 | Crit. Care Med. | pmid:21613857 |
Bai Y et al. | Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. | 2011 | Aliment. Pharmacol. Ther. | pmid:21615438 |
Jessick AM et al. | Optimization of analytical methods to improve detection of erythromycin from water and sediment. | 2011 | J Environ Sci Health B | pmid:21877980 |
Ergin A et al. | Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases. | 2011 | New Microbiol. | pmid:21617831 |
Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
Garber NC et al. | Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. | 2011 | Adv. Exp. Med. Biol. | pmid:21618111 |
Tazi A et al. | Invasive group B streptococcal infections in adults, France (2007-2010). | 2011 | Clin. Microbiol. Infect. | pmid:21883671 |
Sugiyama E et al. | The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. | 2011 | J Pharm Sci | pmid:21618542 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Imperi M et al. | Invasive neonatal GBS infections from an area-based surveillance study in Italy. | 2011 | Clin. Microbiol. Infect. | pmid:21722258 |
Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
You L et al. | Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. | 2011 | Nat Chem | pmid:22109274 |
Braga TM et al. | Involvement, and dissemination, of the enterococcal small multidrug resistance transporter QacZ in resistance to quaternary ammonium compounds. | 2011 | J. Antimicrob. Chemother. | pmid:21147826 |
Allen VG et al. | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. | 2011 | Antimicrob. Agents Chemother. | pmid:21098249 |
Miller E et al. | Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. | 2011 | Lancet Infect Dis | pmid:21621466 |
Song W et al. | A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering. | 2011 | J Biomed Mater Res A | pmid:21626667 |
Wingard JB et al. | A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. | 2011 | Antimicrob. Agents Chemother. | pmid:21628536 |
Amachawadi RG et al. | Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. | 2011 | Appl. Environ. Microbiol. | pmid:21705534 |
Wenzel F et al. | Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). | 2011 | Clin. Hemorheol. Microcirc. | pmid:22214710 |
Amarir-Bouhram J et al. | Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. | 2011 | PLoS ONE | pmid:22194937 |
Buendia J et al. | Preparation of diastereomerically pure dilignol model compounds. | 2011 | Chemistry | pmid:22076640 |
Louvet JN et al. | Simultaneous Gram and viability staining on activated sludge exposed to erythromycin: 3D CLSM time-lapse imaging of bacterial disintegration. | 2011 | Int J Hyg Environ Health | pmid:21420358 |
Serdoz F et al. | Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss). | 2011 | Eur J Pharm Biopharm | pmid:21402156 |
Marjanović N et al. | Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. | 2011 | Pharmacol. Res. | pmid:21315154 |
Siibak T et al. | Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. | 2011 | Mol. Microbiol. | pmid:21320180 |
Veiga-Crespo P et al. | Synergism between outer membrane proteins and antimicrobials. | 2011 | Antimicrob. Agents Chemother. | pmid:21321143 |
Kataoka M et al. | Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. | 2011 | Eur J Pharm Sci | pmid:21963456 |
Hernández y Ballinas A et al. | [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. | 2011 | Ginecol Obstet Mex | pmid:21966834 |
Gupta R et al. | A 14-year-old with rectal bleeding and abdominal pain. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21970991 |
Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
Zou LK et al. | Erythromycin resistance and virulence genes in Enterococcus faecalis from swine in China. | 2011 | New Microbiol. | pmid:21344149 |
Liu L et al. | Disappearance of sexual dimorphism in triptolide metabolism in monosodium glutamate treated neonatal rats. | 2011 | Arzneimittelforschung | pmid:21428244 |
Lee Y et al. | Chemistry and biology of macrolide antiparasitic agents. | 2011 | J. Med. Chem. | pmid:21428405 |
Chen HX et al. | [Compound erythromycin sustained release preparation and its in vitro release]. | 2011 | Yao Xue Xue Bao | pmid:22260035 |
Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |