erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Derrick CW and Dillon HC | Erythromycin therapy for streptococcal pharyngitis. | 1976 | Am. J. Dis. Child. | pmid:766615 |
Bass JW et al. | Antimicrobials in the treatment of acute otitis media. A second clinical trial. | 1973 | Am. J. Dis. Child. | pmid:4632555 |
Disney FA and Pichichero ME | Treatment of Staphylococcus aureus infections in children in office practice. | 1983 | Am. J. Dis. Child. | pmid:6600877 |
Lloyd-Still JD et al. | Erythromycin estolate hepatotoxicity. | 1978 | Am. J. Dis. Child. | pmid:629252 |
Wannamaker LW | Perplexity and precision in the diagnosis of streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:5056872 |
Fischer PR and Shigeoka AO | Familial occurrence of Stevens-Johnson syndrome. | 1983 | Am. J. Dis. Child. | pmid:6604452 |
HUXTABLE KA et al. | STAPHYLOCOCCAL PNEUMONIA IN CHILDHOOD; LONG-TERM FOLLOW-UP. | 1964 | Am. J. Dis. Child. | pmid:14168063 |
Feigin RD et al. | Osteomyelitis of the calcaneus. Report of eight cases. | 1970 | Am. J. Dis. Child. | pmid:5410295 |
Sprauer MA et al. | Prevention of secondary transmission of pertussis in households with early use of erythromycin. | 1992 | Am. J. Dis. Child. | pmid:1733147 |
Dillon HC and Ware JC | Sources and susceptibilities of staphylococci isolated from children. A seven-year survey. | 1981 | Am. J. Dis. Child. | pmid:7234768 |
Breese BB et al. | Streptococcal infections in children. Comparison of the therapeutic effectiveness of erythromycin administered twice daily with erythromycin, penicillin phenoxymethyl, and clindamycin administered three times daily. | 1974 | Am. J. Dis. Child. | pmid:4213398 |
Warkany J | A warfarin embryopathy? | 1975 | Am. J. Dis. Child. | pmid:1121959 |
Davis SD et al. | Partial antibiotic therapy in Haemophilus infuenzae meningitis. Its effect on cerebrospinal fluid abnormalities. | 1975 | Am. J. Dis. Child. | pmid:1080009 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Breese BB et al. | B-hemolytic streptococcal illness. A comparison of the effectiveness of penicillin G, triacetyloleandomycin, and erythromycin estolate. | 1966 | Am. J. Dis. Child. | pmid:5322797 |
Lascari AD et al. | Varicella-like rash associated with Mycoplasma infection. | 1974 | Am. J. Dis. Child. | pmid:4855375 |
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HALTALIN KC and NELSON JD | HAND-FOOT SYNDROME DUE TO STREPTOCOCCAL INFECTION. | 1965 | Am. J. Dis. Child. | pmid:14237416 |
Bass JW et al. | Susceptibility of Bordetella pertussis to nine antimicrobial agents. | 1969 | Am. J. Dis. Child. | pmid:4303822 |
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STEIN AA et al. | LIPID PATTERNS OF ANTIBIOTIC RESISTANT AND SENSITIVE STRAINS OF STAPHYLOCOCCUS AUREUS ASSOCIATED WITH CYSTIC FIBROSIS OF THE PANCREAS. | 1965 | Am. J. Clin. Pathol. | pmid:14334730 |
Haltalin KC et al. | Agar plate dilution method for routine antibiotic susceptibility testing in a hospital laboratory. | 1973 | Am. J. Clin. Pathol. | pmid:4353843 |
Binford JS et al. | A semiautomated microcalorimetric method of antibiotic sensitivity testing. | 1973 | Am. J. Clin. Pathol. | pmid:4631819 |
McCarthy LR and Bottone EJ | Bacteremia and endocarditis caused by satelliting streptococci. | 1974 | Am. J. Clin. Pathol. | pmid:4494487 |
Palutke WA et al. | Legionella feeleii-associated pneumonia in humans. | 1986 | Am. J. Clin. Pathol. | pmid:3751997 |
Barry AL and Fay GD | Evaluation of four disk diffusion methods for antimicrobic susceptibility tests with anaerobic gram-negative bacilli. | 1974 | Am. J. Clin. Pathol. | pmid:4597112 |
Gavan TL | A summary of the bacteriology portion of the 1972 basic, comprehensive, and special, College of American Pathologists (CAP) Quality Evaluation Program. | 1974 | Am. J. Clin. Pathol. | pmid:4601959 |
Bannatyne RM and Randall C | Ecology of 350 isolates of group F Streptococcus. | 1977 | Am. J. Clin. Pathol. | pmid:836625 |
Field LH and Parker CD | Antibiotic susceptibility testing of Bordetella pertussis. | 1980 | Am. J. Clin. Pathol. | pmid:6251713 |
Mulhare PE et al. | A case of acquired factor X deficiency with in vivo and in vitro evidence of inhibitor activity directed against factor X. | 1991 | Am. J. Clin. Pathol. | pmid:1862774 |
Shojania AM and Hornady G | Effect of antimicrobial agents on serum folate assay. | 1969 | Am. J. Clin. Pathol. | pmid:5820975 |
Holloway WJ et al. | Pasteurella multocida infection in man. Report of 21 cases. | 1969 | Am. J. Clin. Pathol. | pmid:4976987 |
Goldberger AC et al. | Suppurative granulomatous lymphadenitis caused by corynebacterium ovis (pseudotuberculosis). | 1981 | Am. J. Clin. Pathol. | pmid:7293970 |
Jamis-Dow CA et al. | Predicting drug interactions in vivo from experiments in vitro. Human studies with paclitaxel and ketoconazole. | 1997 | Am. J. Clin. Oncol. | pmid:9391548 |
Balassoulis G et al. | Efficacy and safety of erythromycin as sclerosing agent in patients with recurrent malignant pleural effusion. | 2008 | Am. J. Clin. Oncol. | pmid:18845999 |
Deloose E et al. | The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. | 2016 | Am. J. Clin. Nutr. | pmid:26817505 |
Finegold SM | Interaction of antimicrobial therapy and intestinal flora. | 1970 | Am. J. Clin. Nutr. | pmid:4319890 |
Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
Bistrian BR | The who, what, where, when, why, and how of early enteral feeding. | 2012 | Am. J. Clin. Nutr. | pmid:22552029 |
Alkhawajah AM | Studies on the antimicrobial activity of juglans regia. | 1997 | Am. J. Chin. Med. | pmid:9288364 |
Orban Z et al. | Erythromycin-induced cardiac toxicity. | 1995 | Am. J. Cardiol. | pmid:7536388 |
Guelon D et al. | QT prolongation and recurrent "torsades de pointes" during erythromycin lactobionate infusion. | 1986 | Am. J. Cardiol. | pmid:3751946 |
Devereux RB et al. | Cost-effectiveness of infective endocarditis prophylaxis for mitral valve prolapse with or without a mitral regurgitant murmur. | 1994 | Am. J. Cardiol. | pmid:7977041 |
Freedman RA et al. | Effect of erythromycin on ventricular arrhythmias and ventricular repolarization in idiopathic long QT syndrome. | 1987 | Am. J. Cardiol. | pmid:3812231 |
McComb JM et al. | Recurrent ventricular tachycardia associated with QT prolongation after mitral valve replacement and its association with intravenous administration of erythromycin. | 1984 | Am. J. Cardiol. | pmid:6486045 |
Dunlop EM | Penicillin and the control of syphilis. | 1974 | Am. Heart J. | pmid:4606895 |
Clark H | An evaluation of antibiotic prophylaxis in cardiac catheterization. | 1969 | Am. Heart J. | pmid:5192402 |
Chennareddy SB et al. | Erythromycin-induced polymorphous ventricular tachycardia with normal QT interval. | 1996 | Am. Heart J. | pmid:8800045 |
Baird RM | Postoperative infections from bacteroides. | 1973 | Am Surg | pmid:4722418 |