erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Sialadenitis D012793 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Microphthalmos D008850 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Angiomatosis D000798 1 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Epidural Abscess D020802 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Myiasis D009198 1 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Choroiditis D002833 1 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Prolapse D011391 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Furunculosis D005667 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Hypoventilation D007040 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Diphtheria D004165 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Gastroparesis D018589 2 associated lipids
Hoarseness D006685 2 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Salpingitis D012488 2 associated lipids
Marfan Syndrome D008382 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Krokidis MG et al. Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. 2014 Antimicrob. Agents Chemother. pmid:24189263
Krishnappa LG et al. Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. 2014 Acta Microbiol Immunol Hung pmid:24939685
Florindo C et al. Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. 2014 Euro Surveill. pmid:24957747
Ye C et al. Correlation between AcrB trimer association affinity and efflux activity. 2014 Biochemistry pmid:24854514
Fröhlicher S et al. Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. 2014 Swiss Med Wkly pmid:24652673
Cai HL et al. Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. 2014 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:24424301
Arenz S et al. Drug sensing by the ribosome induces translational arrest via active site perturbation. 2014 Mol. Cell pmid:25306253
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
Compain F et al. Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. 2014 Antimicrob. Agents Chemother. pmid:25136004
Wagner G et al. [Childhood granulomatous periorificial dermatitis]. 2014 Hautarzt pmid:25115983
Borbón-Esquer EM et al. SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. 2014 Scand. J. Infect. Dis. pmid:24832853
Wang Z et al. High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. 2014 Clin. Microbiol. Infect. pmid:24816168
Allen LN Mild meningococcaemia, pyrexia protocols and a problematic public health response. 2014 BMJ Case Rep pmid:24811106
Mulatu G et al. Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. 2014 Ethiop J Health Sci pmid:24795510
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324
Brenciani A et al. Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. 2014 J. Antimicrob. Chemother. pmid:24343896
Lu WC et al. Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. 2014 Neurol. Sci. pmid:24277204
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
Kuwahara T et al. Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. 2013 J. Cardiovasc. Electrophysiol. pmid:23551640
Lozada LE et al. Development of pyloric stenosis after a 4-day course of oral erythromycin. 2013 Pediatr Emerg Care pmid:23558266
Cuello-García CA et al. Treating BCG-induced disease in children. 2013 Cochrane Database Syst Rev pmid:23440826
Jersild Jespersen M et al. [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. 2013 Ugeskr. Laeg. pmid:23462037
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Guan Y et al. [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23724685
Lanzarotti C and Rossi G Effect of netupitant, a highly selective NK₁ receptor antagonist, on the pharmacokinetics of midazolam, erythromycin, and dexamethasone. 2013 Support Care Cancer pmid:23729226
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Patel AM et al. Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. 2013 Ann. Intern. Med. pmid:23778904
Wasels F et al. Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. 2013 J. Med. Microbiol. pmid:23741023
Kawai Y et al. Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. 2013 Antimicrob. Agents Chemother. pmid:23716043
Yun SH et al. Demodex folliculitis presenting as periocular vesiculopustular rash. 2013 Orbit pmid:23895342
González-Hein G et al. [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. 2013 Rev Chilena Infectol pmid:23677151
Goh S et al. Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. 2013 MBio pmid:24255122
Horácio AN et al. The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. 2013 PLoS ONE pmid:24066064
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
Derrouiche S et al. Process design for wastewater treatment: catalytic ozonation of organic pollutants. 2013 Water Sci. Technol. pmid:24056437
Jiang M et al. Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. 2013 Metab. Eng. pmid:24060454
Gold RM and Lawhon SD Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. 2013 J. Clin. Microbiol. pmid:24025915
Li YY et al. Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. 2013 BMC Genomics pmid:23902230
Link-Gelles R et al. Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. 2013 J. Infect. Dis. pmid:23852588
Pohl O et al. Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. 2013 J Clin Pharm Ther pmid:24102384
Cai G et al. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. 2013 J. Nat. Prod. pmid:24224794
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Chroboczek T et al. Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. 2013 PLoS ONE pmid:24260092
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Kwak HM et al. The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. 2013 Placenta pmid:23465535
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Magee TV et al. Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. 2013 Bioorg. Med. Chem. Lett. pmid:23414806
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Tsujimoto M et al. Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. 2013 Toxins (Basel) pmid:23965431
Gomes DL et al. SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. 2013 J. Med. Microbiol. pmid:23449875
Petráčková D et al. Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. 2013 Microbiologyopen pmid:23996919
Katipoglu-Yazan T et al. Acute impact of erythromycin and tetracycline on the kinetics of nitrification and organic carbon removal in mixed microbial culture. 2013 Bioresour. Technol. pmid:23892149
Liu JF et al. [Effect of erythromycin on electrical activity and gastric emptying of the intrathoracic stomach after esophagectomy for esophageal cancer]. 2013 Zhonghua Wei Chang Wai Ke Za Zhi pmid:24061999
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Javid FA et al. Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. 2013 Eur. J. Pharmacol. pmid:23201066
Goodman CD et al. Chemobiosynthesis of new antimalarial macrolides. 2013 Antimicrob. Agents Chemother. pmid:23208707
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
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Jiang M et al. The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. 2013 J Vis Exp pmid:23354010
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Elens L et al. CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. 2013 Pharmacogenomics pmid:23327575
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