erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Angiomatosis D000798 1 associated lipids
Animal Diseases D000820 2 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Spider Bites D001098 1 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Asthenia D001247 5 associated lipids
Ataxia D001259 20 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Balanitis D001446 4 associated lipids
Bartonella Infections D001474 3 associated lipids
Bile Reflux D001655 2 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blepharitis D001762 4 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Bone Resorption D001862 7 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bradycardia D001919 13 associated lipids
Bronchiectasis D001987 7 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchopneumonia D001996 7 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Bursitis D002062 3 associated lipids
Campylobacter Infections D002169 13 associated lipids
Carbuncle D002270 1 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Cholelithiasis D002769 16 associated lipids
Cholestasis D002779 23 associated lipids
Choline Deficiency D002796 16 associated lipids
Chorioamnionitis D002821 5 associated lipids
Choroiditis D002833 1 associated lipids
Chronic Disease D002908 7 associated lipids
Cleft Palate D002972 9 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Common Cold D003139 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Conjunctivitis D003231 7 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Crohn Disease D003424 12 associated lipids
Cross Infection D003428 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dacryocystitis D003607 1 associated lipids
Death, Sudden D003645 12 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Dermatitis D003872 30 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Diphtheria D004165 2 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Duodenitis D004382 4 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Dysarthria D004401 2 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspepsia D004415 5 associated lipids
Dyspnea D004417 10 associated lipids
Edema D004487 152 associated lipids
Elephantiasis D004604 2 associated lipids
Empyema D004653 3 associated lipids
Endocarditis D004696 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kozak PP et al. Administration of erythromycin to patients on theophylline. 1977 J. Allergy Clin. Immunol. pmid:874213
Ohba M et al. Effect of clarithromycin on the bioavailability of cyclosporin in rats. 1996 Biol. Pharm. Bull. pmid:8741585
Hoppe JE Update of epidemiology, diagnosis, and treatment of pertussis. 1996 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8740851
Ripoll L et al. Interaction of macrolides with alpha dornase during DNA hydrolysis. 1996 J. Antimicrob. Chemother. pmid:8737148
Aubier M et al. Sparfloxacin for the treatment of community-acquired pneumonia: a pooled data analysis of two studies. 1996 J. Antimicrob. Chemother. pmid:8737127
Gómez-Lechón MJ et al. Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis. 1996 Clin. Exp. Allergy pmid:8735873
Shinkai I and Ohta Y New drugs--reports of new drugs recently approved by the FDA. Dirithromycin. 1996 Bioorg. Med. Chem. pmid:8735838
Box SA and Lee MR A systemic reaction following exposure to a pyrethroid insecticide. 1996 Hum Exp Toxicol pmid:8735461
Moore JE et al. Erythromycin-resistant thermophilic Campylobacter species isolated from pigs. 1996 Vet. Rec. pmid:8730692
Lopes Cardoso FL et al. Rhodococcus equi mastoiditis in a patient with AIDS. 1996 Clin. Infect. Dis. pmid:8729214
Brouqui P et al. Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin. 1996 Antimicrob. Agents Chemother. pmid:8726038
Fujii T et al. Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. 1996 Antimicrob. Agents Chemother. pmid:8726037
Champney WS and Burdine R 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. 1996 Antimicrob. Agents Chemother. pmid:8723490
van Hoogdalem EJ et al. Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. 1996 Skin Pharmacol. pmid:8722604
Hall G et al. Elimination of bacteraemia after dental extraction: comparison of erythromycin and clindamycin for prophylaxis of infective endocarditis. 1996 J. Antimicrob. Chemother. pmid:8722544
Khan MA et al. A reverse transcriptase-PCR based assay for in-vitro antibiotic susceptibility testing of Chlamydia pneumoniae. 1996 J. Antimicrob. Chemother. pmid:8722533
Zimmermann T et al. Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam. 1996 Arzneimittelforschung pmid:8720318
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Ferraro AL et al. The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. 1995 Adv. Exp. Med. Biol. pmid:8718607
Mortensen JE and McDowell T Streptococcus pyogenes: resistant, tolerant, neither or both? 1995 Adv. Exp. Med. Biol. pmid:8718606
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Tateishi T et al. Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. 1996 Anesth. Analg. pmid:8712396
Chattopadhyay S et al. Reactivation of denatured proteins by 23S ribosomal RNA: role of domain V. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8710862
Vanderhoof JA et al. Treatment of cyclic vomiting in childhood with erythromycin. 1995 J. Pediatr. Gastroenterol. Nutr. pmid:8708873
Nichterlein T et al. RP 59500, a streptogramin derivative, is effective in murine listeriosis. 1996 J Chemother pmid:8708741
Arranz-Caso JA et al. Prolonged colonic pseudo-obstruction (Ogilvie syndrome) in an older woman resolved with conservative treatment. 1996 J Am Geriatr Soc pmid:8708296
Paz HL et al. Motility agents for the placement of weighted and unweighted feeding tubes in critically ill patients. 1996 Intensive Care Med pmid:8708166
Zanetti S et al. In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. 1996 J. Antimicrob. Chemother. pmid:8707747
Higgins SP Chlamydial infection in women. 1996 Br J Gen Pract pmid:8703535
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McBride MJ and Baker SA Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga. 1996 Appl. Environ. Microbiol. pmid:8702294
Wasteson Y et al. Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. 1996 Vet. Microbiol. pmid:8701576
Cadisch R et al. [Exacerbation of pseudoparalytic myasthenia gravis following azithromycin (Zithromax)]. 1996 Schweiz Med Wochenschr pmid:8701248
Koizumi A et al. [Effect of prolonged administration of erythromycin on the drug sensitivity and the biological properties of Streptococcus pneumoniae]. 1996 Kansenshogaku Zasshi pmid:8699091
Horowitz MS and Smith LG Vegetative bacterial endocarditis on the prolapsing mitral valve. Echocardiographic evaluation. 1977 Arch. Intern. Med. pmid:869651
Hall JE and Harmer M Erythromycin as a prokinetic agent in children. 1996 Anaesthesia pmid:8694177
Sanchez MA and Rorat E Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. 1996 Jul-Aug Acta Cytol. pmid:8693899
Bailey DG et al. Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. 1996 Clin. Pharmacol. Ther. pmid:8689808
Matschiner S et al. Optimization of topical erythromycin formulations by ion pairing. 1995 Skin Pharmacol. pmid:8688198
Burgin S and Spencer DC Bacillary angiomatosis--another South African case. 1996 S. Afr. Med. J. pmid:8685799
Edelman K et al. Detection of Bordetella pertussis by polymerase chain reaction and culture in the nasopharynx of erythromycin-treated infants with pertussis. 1996 Pediatr. Infect. Dis. J. pmid:8684877
El-Chaar GM et al. Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children. 1996 Pediatr. Infect. Dis. J. pmid:8684871
Samulak KM et al. Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults. 1996 Pediatr. Infect. Dis. J. pmid:8684870
Faghih R et al. Synthesis and antibacterial activity of 6-deoxysporeamicin A. 1996 J. Antibiot. pmid:8682729
Griesgraber G et al. 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. 1996 J. Antibiot. pmid:8682724
Davies JS and Penfold JB Campylobacter urinary infection. 1979 Lancet pmid:86820
Backström M and Kuusela AL [Unilateral pulmonary edema in an infant]. 1995 Duodecim pmid:8681845
Sturm A et al. [Treatment of radiotherapy-induced gastroparesis with erythromycin]. 1996 Dtsch. Med. Wochenschr. pmid:8681733
Coulter WA et al. Dental anxiety and the absorption of orally administered erythromycin stearate. 1995 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:8680971
Rowbury RJ et al. Sensitization to acid induced by sodium ions in Escherichia coli: dependence of (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ. 1996 Microbios pmid:8676748
Zhou D and Apicella MA Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. 1996 Gene pmid:8675023
Surrenti E et al. Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. 1996 Dig. Dis. Sci. pmid:8674390
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McMeekin TO and Moschella SL Iatrogenic complications of dermatologic therapy. Primum non nocere. 1979 Med. Clin. North Am. pmid:86664
Lode H et al. Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. 1995 Eur. Respir. J. pmid:8666093
Johnson AP et al. Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. 1996 BMJ pmid:8664623
Aleksandrova AE and Vinogradova TI [Immunotropic activity of antimicrobial agents used in tuberculosis]. 1996 Probl Tuberk pmid:8657696
King DE et al. Effectiveness of erythromycin in the treatment of acute bronchitis. 1996 J Fam Pract pmid:8656171
Packman AM et al. Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. 1996 Int. J. Dermatol. pmid:8655242
Kligman AM The treatment of acne. Part III: antibacterials. 1995 Cutis pmid:8654122
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720
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Vickery CL et al. Bacillary angiomatosis presenting as a nasal mass with epistaxis. 1996 Otolaryngol Head Neck Surg pmid:8649879
Dam M et al. Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. 1996 J. Mol. Biol. pmid:8648637
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Fang CC et al. Erythromycin-induced acute pancreatitis. 1996 J. Toxicol. Clin. Toxicol. pmid:8632521
Cohen LG et al. Erythromycin-induced clozapine toxic reaction. 1996 Arch. Intern. Med. pmid:8629881
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Thompson D and Oster G Use of terfenadine and contraindicated drugs. 1996 JAMA pmid:8614120
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Feierman DE Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes. 1996 Anesth. Analg. pmid:8610902
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The choice of antibacterial drugs. 1996 Med Lett Drugs Ther pmid:8598824
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Lucier TS et al. Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. 1995 Antimicrob. Agents Chemother. pmid:8593017
Bental T et al. Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. 1995 Clin. Infect. Dis. pmid:8589167
Lavy E et al. Minimal inhibitory concentrations for canine isolates and oral absorption of roxythromycin in fed and fasted dogs. 1995 J. Vet. Pharmacol. Ther. pmid:8587159
Radulovic S et al. In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. 1995 Antimicrob. Agents Chemother. pmid:8585746
Hamzehpour MM et al. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. 1995 Antimicrob. Agents Chemother. pmid:8585714
De Serres G et al. Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. 1995 Pediatr. Infect. Dis. J. pmid:8584364
Bortolussi R et al. Clinical course of pertussis in immunized children. 1995 Pediatr. Infect. Dis. J. pmid:8584314
Tinanoff N et al. Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. 1995 J. Clin. Periodontol. pmid:8583017
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Slomiany BL et al. Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. 1995 Scand. J. Gastroenterol. Suppl. pmid:8578215
Masclee AA et al. Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. 1995 Regul. Pept. pmid:8577928