erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tomomasa T et al. | Gastrointestinal sounds and migrating motor complex in fasted humans. | 1999 | Am. J. Gastroenterol. | pmid:10022632 |
| Carbonell N et al. | Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. | 2006 | Am. J. Gastroenterol. | pmid:16771939 |
| Glupczynski Y and Burette A | Failure of azythromycin to eradicate Campylobacter pylori from the stomach because of acquired resistance during treatment. | 1990 | Am. J. Gastroenterol. | pmid:2153337 |
| Janssen P et al. | The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. | 2013 | Am. J. Gastroenterol. | pmid:24005344 |
| Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
| Fiorucci S et al. | Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. | 1994 | Am. J. Gastroenterol. | pmid:8147358 |
| Rayner CK et al. | The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. | 2000 | Am. J. Gastroenterol. | pmid:11007223 |
| Bachman BA et al. | Erythromycin ethylsuccinate-induced cholestasis. | 1982 | Am. J. Gastroenterol. | pmid:6979924 |
| Resnick J et al. | Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. | 1997 | Am. J. Gastroenterol. | pmid:9177505 |
| Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
| Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
| Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
| Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
| Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
| Carmagnola S et al. | Mechanoreceptors of the proximal stomach and perception of gastric distension. | 2005 | Am. J. Gastroenterol. | pmid:16086705 |
| Kalkay MN et al. | Campylobacter-induced toxic megacolon. | 1983 | Am. J. Gastroenterol. | pmid:6613968 |
| Masclee AA et al. | Effect of erythromycin on gallbladder emptying in patients with antrectomy or truncal vagotomy. | 1995 | Am. J. Gastroenterol. | pmid:7771433 |
| Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
| Tanaka M et al. | Agranulocytosis induced by macrolide antibiotics. | 1995 | Am. J. Hematol. | pmid:7847332 |
| Singer DR et al. | Drug hypersensitivity causing granulomatous interstitial nephritis. | 1988 | Am. J. Kidney Dis. | pmid:3354573 |
| MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
| Mery JP and Kanfer A | Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. | 1984 | Am. J. Kidney Dis. | pmid:6741942 |
| Silang R et al. | Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. | 2001 | Am. J. Kidney Dis. | pmid:11157368 |
| Ross EA and Koo LC | Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. | 1998 | Am. J. Kidney Dis. | pmid:9428453 |
| Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
| Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
| Nattel S et al. | Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. | 1990 | Am. J. Med. | pmid:2382671 |
| Naot Y et al. | IgM and IgG antibody response in two immunosuppressed patients with Legionnaires' disease. Evidence of reactivation of latent infection. | 1982 | Am. J. Med. | pmid:6756135 |
| Parker RH et al. | Erythromycin-resistant pneumococcal osteomyelitis. | 1970 | Am. J. Med. | pmid:5415405 |
| Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
| Wong KF et al. | Psittacosis-associated hemophagocytic syndrome. | 1991 | Am. J. Med. | pmid:1867249 |
| Lipsky BA et al. | Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. | 1990 | Am. J. Med. | pmid:2252040 |
| Vianna NJ and Hinman AR | Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. | 1971 | Am. J. Med. | pmid:5129543 |
| DAVIS DS and ROMANSKY MJ | Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. | 1956 | Am. J. Med. | pmid:13354638 |
| Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
| Petersdorf RG | Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? | 1978 | Am. J. Med. | pmid:99033 |
| Moellering RC et al. | Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. | 1974 | Am. J. Med. | pmid:4843895 |
| Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
| Neu HC | Clinical microbiology of azithromycin. | 1991 | Am. J. Med. | pmid:1656736 |
| Stamm WE | Azithromycin in the treatment of uncomplicated genital chlamydial infections. | 1991 | Am. J. Med. | pmid:1656737 |
| Hooton TM | A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. | 1991 | Am. J. Med. | pmid:1656738 |
| Casiano RR | Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. | 1991 | Am. J. Med. | pmid:1656739 |
| Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
| Friedland L et al. | Ocular and pericardial involvement in Legionnaires' disease. | 1984 | Am. J. Med. | pmid:6507461 |
| Wing EJ et al. | Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin. | 1981 | Am. J. Med. | pmid:7304656 |
| Stocks JM et al. | Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. | 1989 | Am. J. Med. | pmid:2690620 |
| Dull JS et al. | Successful treatment of gastroparesis with erythromycin in a patient with progressive systemic sclerosis. | 1990 | Am. J. Med. | pmid:2220887 |
| Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
| Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
| Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |