erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Vassallo M and Shepherd RJ | A case of relapsing psittacosis associated with a stroke. | 1997 | Int. J. Clin. Pract. | pmid:9287275 |
Jadcherla SR et al. | Regulation of migrating motor complexes by motilin and pancreatic polypeptide in human infants. | 1997 | Pediatr. Res. | pmid:9284278 |
Miyata Y et al. | Porphyromonas gingivalis lipopolysaccharide-stimulated bone resorption via CD14 is inhibited by broad-spectrum antibiotics. | 1997 | Infect. Immun. | pmid:9284114 |
Nishijima S and Nakagawa M | Sensitivity of antibacterials of Staphylococcus aureus isolated from impetigo patients. | 1997 Jul-Aug | J. Int. Med. Res. | pmid:9283995 |
Pemberton M et al. | Treating oral candidiasis: potentially fatal. | 1997 | Br Dent J | pmid:9282448 |
Wang X et al. | [Effects of changes of plasma motilin level on the motility of gallbladder in patients with chronic renal failure]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9275623 |
Hu H et al. | A case of diffuse panbronchiolitis. | 1996 | Chin. Med. J. | pmid:9275329 |
Anderson KL | Genetic manipulation of anaerobic cellulolytic bacteria. | 1997 | SAAS Bull. Biochem. Biotechnol. | pmid:9274059 |
Schaller U et al. | [Ophthalmia neonatorum caused by Chlamydia trachomatis. Rapid diagnosis and therapy]. | 1997 | Ophthalmologe | pmid:9273028 |
Wirsing von König CH et al. | Factors influencing the analysis of secondary prevention of pertussis. | 1997 | Dev. Biol. Stand. | pmid:9272349 |
Takahashi Y et al. | Effects of indomethacin, dexamethasone, and erythromycin on endotoxin-induced intraepithelial mucus production of rat nasal epithelium. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9270434 |
Cazzola M et al. | A five-day course of dirithromycin in the treatment of acute exacerbation of severe chronic obstructive pulmonary disease. | 1997 | J Chemother | pmid:9269609 |
Sorkine P et al. | Gut decontamination reduces bowel ischemia-induced lung injury in rats. | 1997 | Chest | pmid:9266889 |
Szklarz GD and Halpert JR | Molecular modeling of cytochrome P450 3A4. | 1997 | J. Comput. Aided Mol. Des. | pmid:9263853 |
Dajani AS et al. | Prevention of bacterial endocarditis: recommendations by the American Heart Association. | 1997 | J Am Dent Assoc | pmid:9260427 |
Ogasawara KK and Goodwin TM | The efficacy of prophylactic erythromycin in preventing vertical transmission of Ureaplasma urealyticum. | 1997 | Am J Perinatol | pmid:9259934 |
Fuursted K | Postexposure factors influencing the duration of postantibiotic effect: significance of temperature, pH, cations, and oxygen tension. | 1997 | Antimicrob. Agents Chemother. | pmid:9257743 |
Rouse MS et al. | Efficacy of azithromycin or clarithromycin for prophylaxis of viridans group streptococcus experimental endocarditis. | 1997 | Antimicrob. Agents Chemother. | pmid:9257739 |
Brunke KJ et al. | A technique for the rapid selection of drug-sensitive and auxotrophic mutants of Phycomyces blakesleeanus. | 1977 | J. Gen. Microbiol. | pmid:925680 |
Baty V et al. | Legionella jordanis pneumonia unresponsive to fluoroquinolones in a non-immunocompromised host. | 1997 | Scand. J. Infect. Dis. | pmid:9255901 |
Schugk J et al. | A clinical study of beta-haemolytic groups A, B, C and G streptococcal bacteremia in adults over an 8-year period. | 1997 | Scand. J. Infect. Dis. | pmid:9255881 |
Boyer PJ | Outbreak of clinical mastitis in dairy cows following 'blitz' therapy. | 1997 | Vet. Rec. | pmid:9253837 |
Peterson LR et al. | Standardization of a preparative ultracentrifuge method for quantitative determination or protein binding of seven antibiotics. | 1977 | J. Infect. Dis. | pmid:925383 |
Goossens C et al. | Baboon syndrome. | 1997 | Dermatology (Basel) | pmid:9252782 |
Ridlen JS et al. | Determination of erythromycin in urine and plasma using microbore liquid chromatography with tris(2,2'-bipyridyl)ruthenium(II) electrogenerated chemiluminescence detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9252054 |
Swartz MN | Use of antimicrobial agents and drug resistance. | 1997 | N. Engl. J. Med. | pmid:9250853 |
Seppälä H et al. | The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. Finnish Study Group for Antimicrobial Resistance. | 1997 | N. Engl. J. Med. | pmid:9250845 |
Barry AL et al. | Macrolide resistance among Streptococcus pneumoniae and Streptococcus pyogenes isolates from out-patients in the USA. | 1997 | J. Antimicrob. Chemother. | pmid:9249220 |
Bonnefoy A et al. | Ketolides lack inducibility properties of MLS(B) resistance phenotype. | 1997 | J. Antimicrob. Chemother. | pmid:9249208 |
Pereda A et al. | Nucleotide sequence of the ermE distal flank of the erythromycin biosynthesis cluster in Saccharopolyspora erythraea. | 1997 | Gene | pmid:9249068 |
Rapoport N et al. | Factors affecting the permeability of Pseudomonas aeruginosa cell walls toward lipophilic compounds: effects of ultrasound and cell age. | 1997 | Arch. Biochem. Biophys. | pmid:9244388 |
Hofstetter A et al. | [Treatment of chlamydial urethro-adnexitis with erythromycin]. | 1977 | Fortschr. Med. | pmid:924327 |
Berk SL | Therapy for severe community-acquired pneumonia. | 1997 | Clin. Infect. Dis. | pmid:9243063 |
Altomare DF et al. | Oral erythromycin improves gastrointestinal motility and transit after subtotal but not total gastrectomy for cancer. | 1997 | Br J Surg | pmid:9240156 |
Herdy GV et al. | [Secondary prophylaxis in rheumatic fever. Oral antibiotic therapy versus benzathine penicillin]. | 1996 | Arq. Bras. Cardiol. | pmid:9239868 |
Seppälä H et al. | Erythromycin resistance of group A streptococci from throat samples is related to age. | 1997 | Pediatr. Infect. Dis. J. | pmid:9239768 |
Oesterheld JR | Erythromycin and clomipramine: noncompetitive inhibition of demethylation. | 1996 | J Child Adolesc Psychopharmacol | pmid:9231314 |
Fisman S et al. | Erythromycin interaction with risperidone or clomipramine in an adolescent. | 1996 | J Child Adolesc Psychopharmacol | pmid:9231305 |
Takizawa H et al. | Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9230759 |
Kobayashi T et al. | Ototoxic effect of erythromycin on cochlear potentials in the guinea pig. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9228863 |
Handsfield HH | Azithromycin in gonorrhoea. | 1997 | Int J STD AIDS | pmid:9228599 |
Sefton AM et al. | The in-vitro activity of trovafloxacin, a new fluoroquinolone, against Gram-positive bacteria. | 1997 | J. Antimicrob. Chemother. | pmid:9222071 |
Onody C et al. | Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila. | 1997 | J. Antimicrob. Chemother. | pmid:9222053 |
Gaudreau C and Gilbert H | Comparison of disc diffusion and agar dilution methods for antibiotic susceptibility testing of Campylobacter jejuni subsp. jejuni and Campylobacter coli. | 1997 | J. Antimicrob. Chemother. | pmid:9222038 |
Hanson MR and Bogorad L | Effects of erythromycin on membrane-bound chloroplast ribosomes from wild-type Chlamydomonas reinhardi and erythromycin-resistant mutants. | 1977 | Biochim. Biophys. Acta | pmid:921999 |
Jacobsen JR et al. | Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase. | 1997 | Science | pmid:9219693 |
Antsaklis A et al. | Erythromycin treatment for subclinical Ureaplasma urealyticum infection in preterm labor. | 1997 Mar-Apr | Fetal. Diagn. Ther. | pmid:9218948 |
Hoppe JE and Tschirner T | Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9218920 |
Annese V et al. | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218089 |
Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |