erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Granovsky-Grisaru S et al. | Effects of erythromycin on contractility of isolated myometrium from pregnant rats. | 1998 | Am. J. Obstet. Gynecol. | pmid:9465824 |
Charles AG et al. | Asymptomatic gonorrhea in prenatal patients. | 1970 | Am. J. Obstet. Gynecol. | pmid:5505990 |
McFarlin BL et al. | Epidemic syphilis: maternal factors associated with congenital infection. | 1994 | Am. J. Obstet. Gynecol. | pmid:8116709 |
Campbell WF and Dodson MG | Clindamycin therapy for Chlamydia trachomatis in women. | 1990 | Am. J. Obstet. Gynecol. | pmid:2178426 |
Yost NP et al. | An appraisal of treatment guidelines for antepartum community-acquired pneumonia. | 2000 | Am. J. Obstet. Gynecol. | pmid:10920320 |
Hussain N and Herson VC | Erythromycin use during pregnancy in relation to pyloric stenosis. | 2002 | Am. J. Obstet. Gynecol. | pmid:12237674 |
Johnson RB | The role of azalide antibiotics in the treatment of Chlamydia. | 1991 | Am. J. Obstet. Gynecol. | pmid:1645503 |
Romero R et al. | Eradication of Ureaplasma urealyticum from the amniotic fluid with transplacental antibiotic treatment. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536243 |
Danielian P | Erythromycin, motilin, and meconium. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536263 |
Goldberg JD and Golbus MS | The value of case reports in human teratology. | 1986 | Am. J. Obstet. Gynecol. | pmid:3456709 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
Mercer BM et al. | The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. | 2012 | Am. J. Obstet. Gynecol. | pmid:22000668 |
Mercer BM et al. | Erythromycin therapy in preterm premature rupture of the membranes: a prospective, randomized trial of 220 patients. | 1992 | Am. J. Obstet. Gynecol. | pmid:1550145 |
McGregor JA et al. | Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial. | 1986 | Am. J. Obstet. Gynecol. | pmid:3511709 |
Tarnow-Mordi W et al. | Randomized controlled trials of antibiotics in preterm labor. | 1994 | Am. J. Obstet. Gynecol. | pmid:8092243 |
Rao KV and Ralston RA | Meningitis due to Campylobacter fetus intestinalis in a kidney transplant recipient. A case report. | 1987 | Am. J. Nephrol. | pmid:3324765 |
SOLOMON S and JOHNSTON B | The clinical use of erythromycin. | 1955 | Am. J. Med. Sci. | pmid:13268445 |
Kislak JW et al. | Susceptibility of pneumococci to nine antibiotics. | 1965 | Am. J. Med. Sci. | pmid:4378532 |
Kayser FH and Mak TM | Methicillin-resistant staphylococci. | 1972 | Am. J. Med. Sci. | pmid:4486503 |
AUSTRIAN R and ROSENBLUM R | The relative efficacy of erythromycin (ilotycin) and of penicillin in the treatment of pneumococcal lobar pneumonia. | 1953 | Am. J. Med. Sci. | pmid:13104398 |
Simon HJ | Antimicrobial susceptibility of group D hemolytic streptococci (enterococci). | 1967 | Am. J. Med. Sci. | pmid:5180810 |
BLOUGH HA et al. | Serum levels and clinical results with erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:13801645 |
CICCANTELLI MJ and GARRY MW | Erythromycin: an evaluation for clinical toxicity. | 1956 | Am. J. Med. Sci. | pmid:13362260 |
ROBINSON MM | Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate. | 1962 | Am. J. Med. Sci. | pmid:14492926 |
Devasia RA et al. | Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. | 2009 | Am. J. Med. Sci. | pmid:19301451 |
Williams ME et al. | Legionnaires' disease with acute renal failure. | 1980 May-Jun | Am. J. Med. Sci. | pmid:7424965 |
Toala P et al. | Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. | 1969 | Am. J. Med. Sci. | pmid:4984452 |
HIRSCH HA and FINLAND M | Effect of food on the absorption of erythromycin propionate, erythromycin stearate and triacetyloleandomycin. | 1959 | Am. J. Med. Sci. | pmid:13661157 |
Holoshitz J et al. | Listeria monocytogenes pericarditis in a chronically hemodialyzed patient. | 1984 Jul-Aug | Am. J. Med. Sci. | pmid:6465192 |
Feigin RD et al. | Treatment of penicillin-resistant staphylococcal infections with clindamycin. | 1971 | Am. J. Med. Sci. | pmid:5578775 |
GRIFFITH RS and BLACK HR | COMPARISON OF THE BLOOD LEVELS OBTAINED AFTER SINGLE AND MULTIPLE DOSES OF ERYTHROMYCIN ESTOLATE AND ERYTHROMYCIN STEARATE. | 1964 | Am. J. Med. Sci. | pmid:14106882 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
HIRSCH HA et al. | Effect of food on absorption of a new form of erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:14401969 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Oppenheimer S and Turek M | Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. | 1968 | Am. J. Med. Sci. | pmid:4386951 |
CLAPPER WE et al. | THE SUSCEPTIBILITY OF CERTAIN BACTERIA TO LINCOMYCIN AS RELATED TO ATTAINABLE SERUM LEVELS IN HUMAN ADULTS. | 1964 | Am. J. Med. Sci. | pmid:14130319 |
FISCHER HW and HOAK JC | MIMICRY OF ACUTE CHOLECYSTITIS BY ERYTHROMYCIN ESTOLATE REACTIONS. REPORT OF 2 CASES. | 1964 | Am. J. Med. Sci. | pmid:14130320 |
McCabe WR and Lorian V | Comparison of the antibacterial activity of rifampicin and other antibiotics. | 1968 | Am. J. Med. Sci. | pmid:4387027 |
Martinez JA et al. | Diffuse panbronchiolitis in Latin America. | 2000 | Am. J. Med. Sci. | pmid:10746829 |
Baird IM et al. | Case report. Clinical manifestations and treatment of Legionnaires' disease. | 1979 Mar-Apr | Am. J. Med. Sci. | pmid:463949 |
Gray BM | Case report: Rhodococcus equi pneumonia in a patient infected by the human immunodeficiency virus. | 1992 | Am. J. Med. Sci. | pmid:1595781 |
Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
Parker RH et al. | Erythromycin-resistant pneumococcal osteomyelitis. | 1970 | Am. J. Med. | pmid:5415405 |
Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
Wong KF et al. | Psittacosis-associated hemophagocytic syndrome. | 1991 | Am. J. Med. | pmid:1867249 |
DAVIS DS and ROMANSKY MJ | Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. | 1956 | Am. J. Med. | pmid:13354638 |
Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |