erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Angiomatosis D000798 1 associated lipids
Animal Diseases D000820 2 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Spider Bites D001098 1 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Asthenia D001247 5 associated lipids
Ataxia D001259 20 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Balanitis D001446 4 associated lipids
Bartonella Infections D001474 3 associated lipids
Bile Reflux D001655 2 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blepharitis D001762 4 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Bone Resorption D001862 7 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bradycardia D001919 13 associated lipids
Bronchiectasis D001987 7 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchopneumonia D001996 7 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Bursitis D002062 3 associated lipids
Campylobacter Infections D002169 13 associated lipids
Carbuncle D002270 1 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Cholelithiasis D002769 16 associated lipids
Cholestasis D002779 23 associated lipids
Choline Deficiency D002796 16 associated lipids
Chorioamnionitis D002821 5 associated lipids
Choroiditis D002833 1 associated lipids
Chronic Disease D002908 7 associated lipids
Cleft Palate D002972 9 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Common Cold D003139 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Conjunctivitis D003231 7 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Crohn Disease D003424 12 associated lipids
Cross Infection D003428 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dacryocystitis D003607 1 associated lipids
Death, Sudden D003645 12 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Dermatitis D003872 30 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Diphtheria D004165 2 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Duodenitis D004382 4 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Dysarthria D004401 2 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspepsia D004415 5 associated lipids
Dyspnea D004417 10 associated lipids
Edema D004487 152 associated lipids
Elephantiasis D004604 2 associated lipids
Empyema D004653 3 associated lipids
Endocarditis D004696 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
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Bowie WR et al. Efficacy of treatment regimens for lower urogenital Chlamydia trachomatis infection in women. 1982 Am. J. Obstet. Gynecol. pmid:7055176
McGregor JA et al. Cervicovaginal microflora and pregnancy outcome: results of a double-blind, placebo-controlled trial of erythromycin treatment. 1990 Am. J. Obstet. Gynecol. pmid:2240110
KIEFER L et al. The placental transfer of erythomycin. 1955 Am. J. Obstet. Gynecol. pmid:13218094
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Beckner RR et al. Ototoxicity of erythromycin gluceptate. 1981 Am. J. Obstet. Gynecol. pmid:7211980
McFarlin BL et al. Epidemic syphilis: maternal factors associated with congenital infection. 1994 Am. J. Obstet. Gynecol. pmid:8116709
Gauthier DW et al. Expectant management of premature rupture of membranes with amniotic fluid cultures positive for Ureaplasma urealyticum alone. 1994 Am. J. Obstet. Gynecol. pmid:8116718
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Silverman NS et al. A randomized, prospective trial comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. 1994 Am. J. Obstet. Gynecol. pmid:8141211
Friberg J Genital mycoplasma infections. 1978 Am. J. Obstet. Gynecol. pmid:362924
Klebanoff MA et al. Outcome of the Vaginal Infections and Prematurity Study: results of a clinical trial of erythromycin among pregnant women colonized with group B streptococci. 1995 Am. J. Obstet. Gynecol. pmid:7755068
Alger LS and Lovchik JC Comparative efficacy of clindamycin versus erythromycin in eradication of antenatal Chlamydia trachomatis. 1991 Am. J. Obstet. Gynecol. pmid:1872343
Eschenbach DA et al. A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery. The Vaginal Infections and Prematurity Study Group. 1991 Am. J. Obstet. Gynecol. pmid:2003533
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Croak A et al. Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio. 2003 Am. J. Obstet. Gynecol. pmid:12748459
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Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
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Kundsin RB et al. Ureaplasma urealyticum resistance to erythromycin: confirmed by clinical trial. 1992 Am. J. Obstet. Gynecol. pmid:1615998
Mercer BM et al. Erythromycin therapy in preterm premature rupture of the membranes: a prospective, randomized trial of 220 patients. 1992 Am. J. Obstet. Gynecol. pmid:1550145
McGregor JA et al. Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial. 1986 Am. J. Obstet. Gynecol. pmid:3511709
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BUTTON RR Treatment of trachoma with erythromycin; a preliminary report of 21 cases. 1955 Am. J. Ophthalmol. pmid:13228536
Okumoto M and Smolin G Pneumococcal infections of the eye. 1974 Am. J. Ophthalmol. pmid:4149786
Maskin SL Infectious scleritis after a diabetic foot ulcer. 1993 Am. J. Ophthalmol. pmid:8430739
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Cunningham ET and Koehler JE Ocular bartonellosis. 2000 Am. J. Ophthalmol. pmid:11020414
HALLETT JW and LEOPOLD IH Clinical trial of erythromycin ophthalmic ointment. 1957 Am. J. Ophthalmol. pmid:13469938
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Cetinkaya A and Akova YA Pediatric ocular acne rosacea: long-term treatment with systemic antibiotics. 2006 Am. J. Ophthalmol. pmid:17056363
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Smith RE et al. Mycobacterium chelonei and orbital granuloma after tear duct probing. 1980 Am. J. Ophthalmol. pmid:7356779
PRATER BG and MOOR WA Erythromycin; a report on a new ophthalmic ointment. 1954 Am. J. Ophthalmol. pmid:13158494
MARR WG et al. Further studies on the effect of agents on regeneration of corneal epithelium. 1954 Am. J. Ophthalmol. pmid:13148284
NAIB K et al. Observations on the ocular effects of erythromycin. 1955 Am. J. Ophthalmol. pmid:14350055
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Chen J et al. Effect of erythromycin on gastric myoelectrical activity in normal human subjects. 1992 Am. J. Physiol. pmid:1636712
Yamada K et al. Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. 1996 Am. J. Physiol. pmid:8997244
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Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Zhao DM et al. Effect of erythromycin on ATP-induced intracellular calcium response in A549 cells. 2000 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:10749750
Ishizawa K et al. Erythromycin increases bactericidal activity of surface liquid in human airway epithelial cells. 2005 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:16148051
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Kondo M et al. Erythromycin inhibits ATP-induced intracellular calcium responses in bovine tracheal epithelial cells. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9806744
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Gorrini M et al. Inhibition of human neutrophil elastase by erythromycin and flurythromycin, two macrolide antibiotics. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11694455
Kudoh S et al. Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. 1998 Am. J. Respir. Crit. Care Med. pmid:9620913
Hayakawa H et al. Bronchiolar disease in rheumatoid arthritis. 1996 Am. J. Respir. Crit. Care Med. pmid:8912776
Carvalho P et al. Effects of erythromycin on the rabbit pleura: its potential role as a pleural sclerosant. 1995 Am. J. Respir. Crit. Care Med. pmid:7697257
Suzuki T et al. Erythromycin inhibits rhinovirus infection in cultured human tracheal epithelial cells. 2002 Am. J. Respir. Crit. Care Med. pmid:11956054
Tamaoki J et al. Effect of erythromycin on endotoxin-induced microvascular leakage in the rat trachea and lungs. 1995 Am. J. Respir. Crit. Care Med. pmid:7735618
Azuma M et al. Role of alpha1-acid glycoprotein in therapeutic antifibrotic effects of imatinib with macrolides in mice. 2007 Am. J. Respir. Crit. Care Med. pmid:17717205
Sato K et al. Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice. 1998 Am. J. Respir. Crit. Care Med. pmid:9517602
Takizawa H et al. Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells. 1997 Am. J. Respir. Crit. Care Med. pmid:9230759
Seemungal TA et al. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. 2008 Am. J. Respir. Crit. Care Med. pmid:18723437
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