erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| DeLorenzo ME et al. | Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. | 2016 | Environ. Toxicol. | pmid:25348372 |
| Xu JY et al. | Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. | 2016 | J. Proteome Res. | pmid:27090497 |
| Benamrouche N et al. | Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. | 2016 | Clin. Microbiol. Infect. | pmid:27585941 |
| Kang CH and So JS | Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. | 2016 | Mar. Pollut. Bull. | pmid:27555484 |
| Rizzotti L et al. | Biocide and antibiotic resistance of Enterococcus faecalis and Enterococcus faecium isolated from the swine meat chain. | 2016 | Food Microbiol. | pmid:27554158 |
| Choe YJ et al. | Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. | 2016 | Vaccine | pmid:27546875 |
| Kang CH et al. | Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. | 2016 | Environ Sci Pollut Res Int | pmid:27543129 |
| Metcalf BJ et al. | Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. | 2016 | Clin. Microbiol. Infect. | pmid:27542334 |
| Tatiya-Aphiradee N et al. | In vivo antibacterial activity of Garcinia mangostana pericarp extract against methicillin-resistant Staphylococcus aureus in a mouse superficial skin infection model. | 2016 | Pharm Biol | pmid:27180784 |
| He M et al. | Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2016 | Lett. Appl. Microbiol. | pmid:27173151 |
| Patel MB et al. | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. | 2016 | Bioorg. Med. Chem. | pmid:27166575 |
| Mendes RE et al. | In Vitro Activity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States. | 2016 | Antimicrob. Agents Chemother. | pmid:27161634 |
| Taylor SJ et al. | A randomised controlled feasibility and proof-of-concept trial in delayed gastric emptying when metoclopramide fails: We should revisit nasointestinal feeding versus dual prokinetic treatment: Achieving goal nutrition in critical illness and delayed gastric emptying: Trial of nasointestinal feeding versus nasogastric feeding plus prokinetics. | 2016 | Clin Nutr ESPEN | pmid:28531392 |
| Tan C et al. | Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. | 2016 | Mediators Inflamm. | pmid:27127346 |
| Zheng Z et al. | Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. | 2016 | J. Antibiot. | pmid:27118243 |
| Argyropoulos P et al. | Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. | 2016 | Biochim. Biophys. Acta | pmid:26592346 |
| Moltó-GarcÃa B et al. | Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women. | 2016 | Maturitas | pmid:26857873 |
| Sari E et al. | Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. | 2016 | Talanta | pmid:26838449 |
| Magnussen MD et al. | Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. | 2016 | APMIS | pmid:26833774 |
| Seki M et al. | A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy. | 2016 | Intern. Med. | pmid:26831030 |
| Deloose E et al. | The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. | 2016 | Am. J. Clin. Nutr. | pmid:26817505 |
| Liu X et al. | Proteomic response of methicillin-resistant S. aureus to a synergistic antibacterial drug combination: a novel erythromycin derivative and oxacillin. | 2016 | Sci Rep | pmid:26806358 |
| Prabhasankar VP et al. | Removal rates of antibiotics in four sewage treatment plants in South India. | 2016 | Environ Sci Pollut Res Int | pmid:26797959 |
| Zhou J et al. | A seventeen-year observation of the antimicrobial susceptibility of clinical Campylobacter jejuni and the molecular mechanisms of erythromycin-resistant isolates in Beijing, China. | 2016 | Int. J. Infect. Dis. | pmid:26594011 |
| Maye S et al. | Transformation of serum-susceptible Escherichia coli O111 with p16Slux plasmid to allow for real-time monitoring of complement-based inactivation of bacterial growth in bovine milk. | 2016 | J. Dairy Sci. | pmid:26585477 |
| Ohbatake Y et al. | Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. | 2016 | Clin. Exp. Med. | pmid:26359244 |
| Templeton I et al. | A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. | 2016 | Biopharm Drug Dispos | pmid:26356245 |
| Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
| Czarnetzki C et al. | Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. | 2015 | JAMA Surg | pmid:26083537 |
| Patti MG | Erythromycin Use Before Induction of General Endotracheal Anesthesia. | 2015 | JAMA Surg | pmid:26083012 |
| Ericson JE et al. | Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:25806675 |
| Aydin S et al. | Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. | 2015 | Water Res. | pmid:25792437 |
| Zhu Y et al. | Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". | 2015 | Sci Rep | pmid:25791905 |
| Wang P et al. | Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. | 2015 | PLoS ONE | pmid:25781346 |
| Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
| Chiaverini C et al. | Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. | 2015 | Br. J. Dermatol. | pmid:25601422 |
| Li Z et al. | New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2015 | Lett. Appl. Microbiol. | pmid:25588530 |
| Gardiner SJ et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2015 | Cochrane Database Syst Rev | pmid:25566754 |
| Azadegan A et al. | Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. | 2015 | Ann Lab Med | pmid:25553281 |
| Wu H et al. | Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25549616 |
| Wang Z et al. | Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. | 2015 | Food Chem | pmid:25308648 |
| Hawkins PA et al. | Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. | 2015 | Microb. Drug Resist. | pmid:25115711 |
| Vallianou N et al. | Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. | 2015 | J Chemother | pmid:25112954 |
| Yang J et al. | Improving heterologous polyketide production in Escherichia coli by transporter engineering. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26062534 |
| Pavlova A and Gumbart JC | Parametrization of macrolide antibiotics using the force field toolkit. | 2015 | J Comput Chem | pmid:26280362 |
| Feng T et al. | Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. | 2015 | J. Comput. Aided Mol. Des. | pmid:26564143 |
| Daghighi S et al. | Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. | 2015 | Int. J. Antimicrob. Agents | pmid:26526893 |
| Bravo-Rodriguez K et al. | Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. | 2015 | Chem. Biol. | pmid:26526102 |
| Wróblewska M and Winnicka K | The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. | 2015 | Int J Mol Sci | pmid:26343637 |
| Bolukaoto JY et al. | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | 2015 | BMC Res Notes | pmid:26289147 |