erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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D'Souza P et al. | A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. | 1998 | Sex Transm Dis | pmid:9662762 |
Robson HG et al. | Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. | 1983 Jul-Sep | Sex Transm Dis | pmid:6648747 |
McNeeley SG et al. | Treatment of chlamydial infections of the cervix during pregnancy. | 1989 Apr-Jun | Sex Transm Dis | pmid:2740961 |
Osser S and Persson K | Postabortal infectious morbidity after antibiotic treatment of chlamydia-positive patients. | 1989 Apr-Jun | Sex Transm Dis | pmid:2740963 |
Rathbun KC | Congenital syphilis: a proposal for improved surveillance, diagnosis, and treatment. | 1983 Apr-Jun | Sex Transm Dis | pmid:6658628 |
Smith KJ et al. | Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies. | 2007 | Sex Transm Dis | pmid:18077847 |
Jamkhedkar PP et al. | Clinico-epidemiologic features of granuloma inguinale in the era of acquired immune deficiency syndrome. | 1998 | Sex Transm Dis | pmid:9564722 |
The National Gonorrhea Therapy Monitoring Study: II. Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. | 1979 Apr-Jun | Sex Transm Dis | pmid:158832 | |
Goodhart GL | Treatment of uncomplicated genital gonorrhea. | 1979 Apr-Jun | Sex Transm Dis | pmid:158833 |
Bowie WR and Willetts V | Suboptimal efficacy of erythromycin and tetracycline against vaginal Ureaplasma urealyticum. | 1987 Apr-Jun | Sex Transm Dis | pmid:3112969 |
Ibsen HH et al. | Treatment of nongonococcal urethritis: comparison of ofloxacin and erythromycin. | 1989 Jan-Mar | Sex Transm Dis | pmid:2667153 |
Sanders CJ and Mulder MM | Periurethral gland abscess: aetiology and treatment. | 1998 | Sex Transm Infect | pmid:9924469 |
Romoren M et al. | Costs and health consequences of chlamydia management strategies among pregnant women in sub-Saharan Africa. | 2007 | Sex Transm Infect | pmid:17932126 |
Romoren M et al. | Chlamydia and gonorrhoea in pregnancy: effectiveness of diagnosis and treatment in Botswana. | 2004 | Sex Transm Infect | pmid:15459410 |
National guideline for the management of Chlamydia trachomatis genital tract infection. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616372 | |
National guideline for the management of non-gonococcal urethritis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases) | 1999 | Sex Transm Infect | pmid:10616373 | |
National guideline for the management of early syphilis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616379 | |
National guideline for the management of lymphogranuloma venereum. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616382 | |
National guideline for the management of chancroid. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616383 | |
Shi XZ and Zhang JJ | [Erythromycin: a motilin receptor agonist]. | 1992 | Sheng Li Ke Xue Jin Zhan | pmid:1302371 |
Zhang BC et al. | [Construction of Saccharopolyspora erythraea M synthesizing a novel ketolide 3-deoxy-3-oxo-erythronolide B]. | 2002 | Sheng Wu Gong Cheng Xue Bao | pmid:12148283 |
Peng QZ et al. | [The construction of shuttle vectors of Brevibacillus brevis-Escherichia coli]. | 2002 | Sheng Wu Gong Cheng Xue Bao | pmid:12385239 |
Qin XY et al. | Involvement of dopamine D3 and neuropeptide Y Y5 receptors in diabetic gastroparetic rats without response to erythromycin. | 2003 | Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao | pmid:12958653 |
Kato C and Saito K | [Effect of antibiotics on intracellular bacteria. 2. Effect of antibiotic treatment on Staphylococcus aureus 209P phagocytized by mouse polymorphonuclear leukocytes]. | 1985 | Shigaku | pmid:3857540 |
Kitagawa J et al. | [Use of Erythrocin Chewable in the dental field]. | 1978 | Shikai Tenbo | pmid:295884 |
Suzuki S et al. | [Clinical effects of erythrocin for the infectious diseases of the mouth]. | 1978 | Shikai Tenbo | pmid:295915 |
Kotani J et al. | [Use of erythromycin in the dental field]. | 1979 | Shikai Tenbo | pmid:295958 |
Haraguchi I et al. | [Clinico-pathological study on the effect of erythromycin on pulp tissue]. | 1967 | Shikwa Gakuho | pmid:5236258 |
FUKUHARA F et al. | [THREE CASES OF IDIOPATHIC HYPOPLASTIC ANEMIA, ESPECIALLY THOSE SEEN IN INFANCY]. | 1963 Jan-Feb | Shonika Kiyo | pmid:14043578 |
OKUBO Y et al. | [FOUR CASES OF "STAPHYLOCOCCAL SCARLET FEVER"]. | 1963 Jul-Aug | Shonika Kiyo | pmid:14083896 |
SAITO M | [CLINICAL FINDINGS OF BACTERIAL FOOD POISONING CAUXED BY VIBRIO PARAHAEMOLYTICUS]. | 1963 | Showa Igakkai Zasshi | pmid:14157123 |
Li F et al. | [An experimental study of gastric pacing on postsurgical gastric dynamic dysfunction]. | 2003 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:12947728 |
Du Y and He Q | [Molecular mechanism of erythromycin in the improvement of paraquat-damaged vascular endothelial cell barrier function]. | 2009 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:20067116 |
Mohammadizadeh M et al. | Efficacy of prophylactic oral erythromycin to improve enteral feeding tolerance in preterm infants: a randomised controlled study. | 2010 | Singapore Med J | pmid:21221501 |
Soong TW et al. | Characterization of plasmids from clinical isolates of Bacteroides. | 1984 | Singapore Med J | pmid:6385275 |
Hui SE and Loo LA | The antibiotic resistance pattern of 192 strains of Staphylococcus aureus. | 1970 | Singapore Med J | pmid:5202464 |
Narendran K | Community acquired mycoplasmal pneumonia. | 1987 | Singapore Med J | pmid:3423800 |
Tan HH et al. | Bacterial skin infections at a tertiary dermatological centre. | 1998 | Singapore Med J | pmid:9844495 |
Cohen MA and Pang JC | A retrospective study of community-acquired pneumonia in Hong Kong with special reference to the choice of antibiotics. | 1989 | Singapore Med J | pmid:2609170 |
Gencoglan G and Ceylan C | Two cases of acneiform eruption induced by inhibitor of epidermal growth factor receptor. | 2007 | Skin Pharmacol Physiol | pmid:17641540 |
van Hoogdalem EJ et al. | Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. | 1996 | Skin Pharmacol. | pmid:8722604 |
van Hoogdalem EJ | Assay of erythromycin in tape strips of human stratum corneum and some preliminary results in man. | 1992 | Skin Pharmacol. | pmid:1637560 |
Matschiner S et al. | Optimization of topical erythromycin formulations by ion pairing. | 1995 | Skin Pharmacol. | pmid:8688198 |
Matschiner S et al. | Influence of ion pairing on ex vivo penetration of erythromycin into sebaceous follicles. | 1996 | Skin Pharmacol. | pmid:8896118 |
Burkhart CN et al. | Synergistic activity of benzoyl peroxide and erythromycin. | 2000 Sep-Oct | Skin Pharmacol. Appl. Skin Physiol. | pmid:10940820 |
Nam C et al. | Anti-acne effects of Oriental herb extracts: a novel screening method to select anti-acne agents. | 2003 Mar-Apr | Skin Pharmacol. Appl. Skin Physiol. | pmid:12637783 |
Dutil M | Benzoyl peroxide: enhancing antibiotic efficacy in acne management. | 2010 Nov-Dec | Skin Therapy Lett. | pmid:21076800 |
Abdal H et al. | The eye in sleep apnea syndrome. | 2006 | Sleep Med. | pmid:16459137 |
Turner WB | Secondary metabolism with special reference to Actinomycetales. | 1973 | Soc. Appl. Bacteriol. Symp. Ser. | pmid:4584096 |
TANAKA N | [ANTIBIOTICS AND NUCLEIC ACIDS]. | 1963 | Sogo Igaku | pmid:14100272 |