erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Pérez RA et al. | Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2017 | J Pharm Biomed Anal | pmid:28858671 |
Zankari E et al. | PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. | 2017 | J. Antimicrob. Chemother. | pmid:29091202 |
Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
Štšepetova J et al. | Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. | 2017 | J. Appl. Microbiol. | pmid:28574626 |
Tanaka Y et al. | Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532245 |
Demczuk WHB et al. | Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. | 2017 | PLoS ONE | pmid:28531208 |
Cheled-Shoval S et al. | From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. | 2017 | Molecules | pmid:28513558 |
Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
Wozniak A et al. | Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. | 2017 | J. Med. Microbiol. | pmid:28463664 |
Pavlova A et al. | Toward the rational design of macrolide antibiotics to combat resistance. | 2017 | Chem Biol Drug Des | pmid:28419786 |
Sugimoto N et al. | Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. | 2017 | BMC Res Notes | pmid:28057059 |
Liu J et al. | Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. | 2017 | Environ Sci Pollut Res Int | pmid:28004371 |
Hillitt KL et al. | Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. | 2017 | Lett. Appl. Microbiol. | pmid:27992658 |
Numanović F et al. | Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. | 2017 | Med Glas (Zenica) | pmid:27917849 |
Pavlović D et al. | Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. | 2017 | Eur J Med Chem | pmid:27657812 |
Lim SK et al. | Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. | 2017 | J. Vet. Med. Sci. | pmid:27593510 |
Ricker EB and Nuxoll E | Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. | 2017 | Biofouling | pmid:29039211 |
Bitew A et al. | Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. | 2017 | BMC Infect. Dis. | pmid:28962545 |
Öksüz L and Gürler N | [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. | 2017 | Mikrobiyol Bul | pmid:28929957 |
Pan M and Chu LM | Transfer of antibiotics from wastewater or animal manure to soil and edible crops. | 2017 | Environ. Pollut. | pmid:28866424 |
Wekselman I et al. | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. | 2017 | Structure | pmid:28689968 |
Truong-Bolduc QC et al. | Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. | 2017 | Antimicrob. Agents Chemother. | pmid:28584148 |
Blackwell GA and Hall RM | The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. | 2017 | Antimicrob. Agents Chemother. | pmid:28533235 |
Atkinson CT et al. | Expression of acquired macrolide resistance genes in Haemophilus influenzae. | 2017 | J. Antimicrob. Chemother. | pmid:28961896 |
Zhou Z et al. | Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. | 2017 | Front Cell Infect Microbiol | pmid:28884090 |
Peng Z et al. | Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. | 2017 | Microbiologyopen | pmid:28799224 |
Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |
Zhao L et al. | Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. | 2017 | J Sep Sci | pmid:28121061 |
Dreno B et al. | Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. | 2017 | Exp. Dermatol. | pmid:28094874 |
Xu JY et al. | Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. | 2016 | J. Proteome Res. | pmid:27090497 |
Benamrouche N et al. | Microbiological and molecular characterization of Corynebacterium diphtheriae isolated in Algeria between 1992 and 2015. | 2016 | Clin. Microbiol. Infect. | pmid:27585941 |
Kang CH and So JS | Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. | 2016 | Mar. Pollut. Bull. | pmid:27555484 |
Rizzotti L et al. | Biocide and antibiotic resistance of Enterococcus faecalis and Enterococcus faecium isolated from the swine meat chain. | 2016 | Food Microbiol. | pmid:27554158 |
Choe YJ et al. | Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. | 2016 | Vaccine | pmid:27546875 |
Kang CH et al. | Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. | 2016 | Environ Sci Pollut Res Int | pmid:27543129 |
He M et al. | Mechanism of synergy between SIPI-8294 and β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2016 | Lett. Appl. Microbiol. | pmid:27173151 |
Patel MB et al. | Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. | 2016 | Bioorg. Med. Chem. | pmid:27166575 |
Mendes RE et al. | In Vitro Activity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States. | 2016 | Antimicrob. Agents Chemother. | pmid:27161634 |
Taylor SJ et al. | A randomised controlled feasibility and proof-of-concept trial in delayed gastric emptying when metoclopramide fails: We should revisit nasointestinal feeding versus dual prokinetic treatment: Achieving goal nutrition in critical illness and delayed gastric emptying: Trial of nasointestinal feeding versus nasogastric feeding plus prokinetics. | 2016 | Clin Nutr ESPEN | pmid:28531392 |
Tan C et al. | Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. | 2016 | Mediators Inflamm. | pmid:27127346 |
Zheng Z et al. | Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. | 2016 | J. Antibiot. | pmid:27118243 |
Argyropoulos P et al. | Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. | 2016 | Biochim. Biophys. Acta | pmid:26592346 |
Sari E et al. | Fabrication of surface plasmon resonance nanosensor for the selective determination of erythromycin via molecular imprinted nanoparticles. | 2016 | Talanta | pmid:26838449 |
Magnussen MD et al. | Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. | 2016 | APMIS | pmid:26833774 |
Seki M et al. | A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy. | 2016 | Intern. Med. | pmid:26831030 |
Deloose E et al. | The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. | 2016 | Am. J. Clin. Nutr. | pmid:26817505 |
Liu X et al. | Proteomic response of methicillin-resistant S. aureus to a synergistic antibacterial drug combination: a novel erythromycin derivative and oxacillin. | 2016 | Sci Rep | pmid:26806358 |
Zhou J et al. | A seventeen-year observation of the antimicrobial susceptibility of clinical Campylobacter jejuni and the molecular mechanisms of erythromycin-resistant isolates in Beijing, China. | 2016 | Int. J. Infect. Dis. | pmid:26594011 |
Ohbatake Y et al. | Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. | 2016 | Clin. Exp. Med. | pmid:26359244 |
Templeton I et al. | A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. | 2016 | Biopharm Drug Dispos | pmid:26356245 |