erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Angiomatosis D000798 1 associated lipids
Animal Diseases D000820 2 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Spider Bites D001098 1 associated lipids
Arthritis D001168 41 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. 1997 Jpn J Antibiot pmid:9597446
Mineshita M et al. [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. 1997 Jpn J Antibiot pmid:9597447
Sato K et al. [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. 1997 Jpn J Antibiot pmid:9597453
Ohara K et al. [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597454
Kobayashi O et al. [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597455
Kondo K et al. [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597456
Kudo S [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. 1997 Jpn J Antibiot pmid:9597457
Tei A et al. [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. 1997 Jpn J Antibiot pmid:9597458
Hoshina S et al. [C kinase activation and induction of HL 60 promyelocytic leukemia cell differentiation caused by roxithromycin]. 1997 Jpn J Antibiot pmid:9597464
Takada T et al. [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. 1997 Jpn J Antibiot pmid:9597465
Kaseta M et al. [Study of therapeutic effects of macrolide antibiotics on patients with anti-HTLV-1 antibody positive DPB (diffuse panbronchitis)]. 1997 Jpn J Antibiot pmid:9597466
Miyashima S et al. [Effects of erythromycin on a mouse hypersensitivity pneumonia model]. 1997 Jpn J Antibiot pmid:9597469
Nonaka M et al. [Effects of macrolide antibiotics on fibroblasts]. 1997 Jpn J Antibiot pmid:9597470
Hori S et al. [Effects of macrolide drugs on endogenous glucocorticoids]. 1997 Jpn J Antibiot pmid:9597471
Hikariyama T et al. [Study of suppression of neutrophil functions and prevention of vascular endothelial injury by macrolide antibiotics]. 1998 Jpn J Antibiot pmid:9597473
Tamaoki J et al. [Effects of macrolide antibiotics on iNOS gene expression and NO production by alveolar macrophages]. 1998 Jpn J Antibiot pmid:9597474
Takeda H et al. [Bone absorption suppression by broad spectrum antibiotics]. 1998 Jpn J Antibiot pmid:9597475
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on adhesion of neutrophils to the airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597483
Nakada K et al. [Therapeutic guideline for diffuse panbronchitis (draft). Subcommittee on Diffuse Lung Diseases, Research Committee on Respiratory Diseases Organized by the Ministry of Health and Welfare]. 1998 Jpn J Antibiot pmid:9597494
Shirai R et al. [Evaluation of the duration of medication with erythromycin for treatment of diffuse panbronchitis--a comparison between interruption of medication and continued administration]. 1998 Jpn J Antibiot pmid:9597496
Kishi K et al. [Study of efficacy of macrolide therapy applied to Kartagener's syndrome]. 1998 Jpn J Antibiot pmid:9597497
Miyazawa T et al. [Mucous pathology and macrolide treatment of paranasal sinusitis in children]. 1998 Jpn J Antibiot pmid:9597499
Okura M et al. [Multicenter study on clinical effects of a small dose of erythromycin on chronic lung disorders of premature infants--single blind comparison of treated and untreated groups. A committee for the Study of EM Therapy for Chronic Lung Diseases of Premature Infants]. 1998 Jpn J Antibiot pmid:9597500
Nishimura J et al. [Effects of erythromycin on Pseudomonas aeruginosa pyocyanine-induced IL-8 production and its biological activity (the 2nd report)]. 1998 Jpn J Antibiot pmid:9597503
Abe S et al. [Effect of macrolides on IL-8 gene expression by cultured airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597504
Sugiyama Y et al. [Changes in cytokine production by pulmonary alveolar macrophages collected from rats that have been treated with erythromycin for an extended period]. 1998 Jpn J Antibiot pmid:9597506
Yoshimine H et al. [Inhibition of neutrophil-derived IL-8 production caused by EM (erythromycin) 201 derivative: modification of the activities by the 5-position desosamine side chain]. 1998 Jpn J Antibiot pmid:9597508
Kozeki S et al. [Study on bacterial biofilm destruction by various antibacterial agents]. 1998 Jpn J Antibiot pmid:9597510
Nakada M et al. [Inhibitory effects of macrolide antibiotics at low concentrations on vero toxin production by pathogenic E. coli O157]. 1998 Jpn J Antibiot pmid:9597511
Kyo S et al. [Effects of macrolides on intracellular Ca2+ response by airway epithelium]. 1998 Jpn J Antibiot pmid:9597513
Tanabe O et al. [Mechanism of erythromycin action on gene expression of airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597514
Muranaka H et al. [Superoxide radical scavenging activity of an erythromycin-iron complex (the second report)]. 1998 Jpn J Antibiot pmid:9597516
Ng P et al. Diffuse panbronchiolitis: case report and review of the literature. 1998 Australas Radiol pmid:9599832
Karrer S et al. [Acne comedonica following radiation therapy]. 1998 Dtsch. Med. Wochenschr. pmid:9601475
Farrell AM et al. Pyoderma gangrenosum of the penis. 1998 Br. J. Dermatol. pmid:9602887
Vachálková A and Novotný L Polarographic testing of carcinogenicity of some chemotherapeutics. 1997 Neoplasma pmid:9605013
Paesen J et al. Study of the stability of erythromycin in a hydrophilic creme basis by liquid chromatography. 1998 J Pharm Biomed Anal pmid:9608426
Kudoh S Erythromycin treatment in diffuse panbronchiolitis. 1998 Curr Opin Pulm Med pmid:9612675
Neubrand M and Sauerbruch T Erythromycin, a motilin agonist, increases postprandial gallbladder emptying during therapy with ursodeoxycholic acid. 1998 Z Gastroenterol pmid:9612923
Gaisser S et al. Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea. 1998 Mol. Gen. Genet. pmid:9613575
Mathis C and Malbert CH Changes in pyloric resistance induced by erythromycin. 1998 Neurogastroenterol. Motil. pmid:9614671
Bourrat E et al. [Rosacea with ocular involvement in a child]. 1996 Ann Dermatol Venereol pmid:9615130
Syphilis--recommended treatment schedules, 1976. 1976 Am Fam Physician pmid:961559
Krone LV The importance of multiple antibiotic coverage for hospitalized patients when the community acquired pneumonia is Legionnaire's disease. 1998 WMJ pmid:9617308
Kudoh S et al. Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. 1998 Am. J. Respir. Crit. Care Med. pmid:9620913
Kruppa A et al. Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. 1998 Dermatology (Basel) pmid:9621142
Widdowson CA and Klugman KP Emergence of the M phenotype of erythromycin-resistant pneumococci in South Africa. 1998 Apr-Jun Emerging Infect. Dis. pmid:9621199
Rosato A et al. A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin. 1998 Antimicrob. Agents Chemother. pmid:9624482
Muli F and Struthers JK Use of a continuous-culture biofilm system to study the antimicrobial susceptibilities of Gardnerella vaginalis and Lactobacillus acidophilus. 1998 Antimicrob. Agents Chemother. pmid:9624489
Kataja J et al. Different erythromycin resistance mechanisms in group C and group G streptococci. 1998 Antimicrob. Agents Chemother. pmid:9624500