erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Counsell H | An abdominal mass in a 4-year-old child. | 2012 | BMJ Case Rep | pmid:22922923 |
Juntunen P et al. | Campylobacter coli isolates from Finnish farrowing farms using aminopenicillins: high prevalence of bla(OXA-61) and β-lactamase production, but low MIC values. | 2012 | Foodborne Pathog. Dis. | pmid:22924522 |
Kwiatkowska B and Maślińska M | Macrolide therapy in chronic inflammatory diseases. | 2012 | Mediators Inflamm. | pmid:22969171 |
Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Janssen BD et al. | Analysis of aminoacyl- and peptidyl-tRNAs by gel electrophoresis. | 2012 | Methods Mol. Biol. | pmid:22736012 |
LeTourneau N et al. | Synthesis and antibacterial activity of desosamine-modified macrolide derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22738632 |
Harvey CJ et al. | Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. | 2012 | J. Am. Chem. Soc. | pmid:22741553 |
Hellmann-Regen J et al. | Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells. | 2012 | Eur Arch Psychiatry Clin Neurosci | pmid:22434147 |
Vendrell D et al. | Accumulation and depletion kinetics of erythromycin in rainbow trout (Oncorhynchus mykiss). | 2012 | Prev. Vet. Med. | pmid:22436556 |
Golparian D et al. | In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea? | 2012 | Antimicrob. Agents Chemother. | pmid:22354296 |
Devlin MJ et al. | Gastric emptying and symptoms of bulimia nervosa: effect of a prokinetic agent. | 2012 | Physiol. Behav. | pmid:22361261 |
Chini P et al. | Effect of azithromycin on small bowel motility in patients with gastrointestinal dysmotility. | 2012 | Scand. J. Gastroenterol. | pmid:22364597 |
Michael M et al. | Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C(14)-erythromycin breath test and the antipyrine clearance test. | 2012 | Cancer Chemother. Pharmacol. | pmid:21626050 |
Chen C et al. | Isolation and characterization of LS1924A, a new analog of emycins. | 2012 | J. Antibiot. | pmid:22569162 |
Mandisodza O et al. | Arcobacter species in diarrhoeal faeces from humans in New Zealand. | 2012 | N. Z. Med. J. | pmid:22522270 |
Gao J et al. | Antibiotic resistance of Streptococcus agalactiae from cows with mastitis. | 2012 | Vet. J. | pmid:22627045 |
Giovanetti E et al. | ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. | 2012 | Antimicrob. Agents Chemother. | pmid:21986826 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
Brill S et al. | Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23035252 |
Kou X et al. | Synthesis, characterization and adsorption behavior of molecularly imprinted nanospheres for erythromycin using precipitation polymerization. | 2012 | J Nanosci Nanotechnol | pmid:23035481 |
Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
Song M et al. | Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea. | 2011 | J. Dermatol. | pmid:21352337 |
Liu BY et al. | Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. | 2011 | Ecotoxicol. Environ. Saf. | pmid:21353704 |
Crivellaro S et al. | Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21353947 |
Kafali H et al. | Recurrence of ovarian cyst after sclerotherapy. | 2011 | Minerva Ginecol | pmid:21311417 |
Ogungbenro K et al. | A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. | 2011 | Pharm. Res. | pmid:20949310 |
Shang Y et al. | Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. | 2011 | Chin. Med. J. | pmid:21362305 |
Pateron D et al. | Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. | 2011 | Ann Emerg Med | pmid:21333385 |
Cai XJ et al. | [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22094097 |
Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
Ridley EJ and Davies AR | Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. | 2011 | Nutrition | pmid:21295944 |
Nguyen NQ et al. | Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. | 2011 | Crit. Care Med. | pmid:21297459 |
Thenmozhi R et al. | Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. | 2011 | J. Basic Microbiol. | pmid:21298675 |
Tosin M et al. | In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. | 2011 | Chem. Commun. (Camb.) | pmid:21301753 |
Mingoia M et al. | Heterogeneity of Tn5253-like composite elements in clinical Streptococcus pneumoniae isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21263055 |
Song W et al. | Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. | 2011 | Int J Nanomedicine | pmid:22228990 |
Nielsen EI et al. | Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. | 2011 | Antimicrob. Agents Chemother. | pmid:21807983 |
Gardner L et al. | Photochemical control of bacterial signal processing using a light-activated erythromycin. | 2011 | Mol Biosyst | pmid:21785768 |
Srinivasan U et al. | Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. | 2011 | Microb. Drug Resist. | pmid:21166574 |
DeDea L | Erythromycin for GI motility; sunscreens; enoxaparin in obesity. | 2011 | JAAPA | pmid:21850912 |
Maeda Y et al. | Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. | 2011 | J. Med. Microbiol. | pmid:21852527 |
Khan NW et al. | Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. | 2011 | Pak J Pharm Sci | pmid:21190914 |
Chen Y et al. | Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. | 2011 | Drug Metab. Dispos. | pmid:21835977 |
Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
Lee HY et al. | Improved precursor-directed biosynthesis in E. coli via directed evolution. | 2011 | J. Antibiot. | pmid:21081955 |
Wu J et al. | Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. | 2011 | Appl. Environ. Microbiol. | pmid:21841022 |
Senthilkumaran S and Subramanian PT | Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. | 2011 | Indian Pediatr | pmid:22711153 |
Dixon-Woods M et al. | Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. | 2011 | Clin Trials | pmid:21730081 |
Akshay S et al. | Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. | 2011 | Antimicrob. Agents Chemother. | pmid:21730122 |
Daram SR and Garretson R | Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. | 2011 | Gastrointest. Endosc. | pmid:21704823 |
Ma X et al. | Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. | 2011 | Eur J Med Chem | pmid:21855183 |
Soehnlen MK et al. | In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. | 2011 | J. Vet. Diagn. Invest. | pmid:21908288 |
Andini N and Nash KA | Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. | 2011 | FEMS Microbiol. Lett. | pmid:21718348 |
Brodesser S and Kolter T | Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. | 2011 | J Lipids | pmid:21490810 |
Motoyama M et al. | Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. | 2011 | Chemosphere | pmid:21570103 |
Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
Haenni M et al. | ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. | 2011 | Vet. J. | pmid:20667752 |
Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
Spurling GK et al. | Antibiotics for bronchiolitis in children. | 2011 | Cochrane Database Syst Rev | pmid:21678346 |
Palmieri C et al. | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. | 2011 | Antimicrob. Agents Chemother. | pmid:21115784 |
Matsson EM et al. | Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. | 2011 | J Clin Pharmacol | pmid:20663994 |
Bosnjakovic A et al. | Poly(amidoamine) dendrimer-erythromycin conjugates for drug delivery to macrophages involved in periprosthetic inflammation. | 2011 | Nanomedicine | pmid:21059404 |
Bonofiglio L et al. | Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. | 2011 | Microb. Drug Resist. | pmid:21128835 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Altraif I et al. | Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. | 2011 | Gastrointest. Endosc. | pmid:21145052 |
Bopp LH et al. | Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21146719 |
Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
Fry DE | Colon preparation and surgical site infection. | 2011 | Am. J. Surg. | pmid:21429471 |
de Morais e Silva FA et al. | Rosacea fulminans in pregnancy with ocular perforation. | 2011 | J Dtsch Dermatol Ges | pmid:21366860 |
Serisier DJ and Martin ML | Long-term, low-dose erythromycin in bronchiectasis subjects with frequent infective exacerbations. | 2011 | Respir Med | pmid:21367595 |
Almofti YA et al. | Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni. | 2011 | Microb. Pathog. | pmid:21377522 |
Luo DQ et al. | In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. | 2011 | Chemotherapy | pmid:21430380 |
Ma L et al. | Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. | 2011 | PLoS ONE | pmid:21483738 |
Xiong L et al. | Lignans and neolignans from Sinocalamus affinis and their absolute configurations. | 2011 | J. Nat. Prod. | pmid:21469695 |
Yongsheng J et al. | Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y). | 2011 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:21336720 |
Lobanov KV et al. | Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications. | 2011 | Acta Naturae | pmid:22649686 |
Aknin LB et al. | It's the recipient that counts: spending money on strong social ties leads to greater happiness than spending on weak social ties. | 2011 | PLoS ONE | pmid:21347326 |
Pérez-Trallero E et al. | In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21343452 |
Filić D et al. | Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. | 2011 | J Pharm Sci | pmid:21394721 |
Manneck T et al. | Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. | 2011 | Exp. Parasitol. | pmid:20732321 |
van den Bosch S et al. | Erythromycin to promote bedside placement of a self-propelled nasojejunal feeding tube in non-critically ill patients having pancreatitis: a randomized, double-blind, placebo-controlled study. | 2011 | Nutr Clin Pract | pmid:21447772 |
Wang SM et al. | Clinical significance of erythromycin-resistant Campylobacter jejuni in children. | 2011 | J Microbiol Immunol Infect | pmid:21531355 |
Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
Boghigian BA et al. | Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. | 2011 | Biotechnol. Bioeng. | pmid:21337322 |
Zhao DL et al. | Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. | 2011 | Microb. Cell Fact. | pmid:21542941 |
Gannon M et al. | Clinical inquiries. Which oral antibiotics are best for acne? | 2011 | J Fam Pract | pmid:21544278 |
Chia HY et al. | Follicular spicules associated with Propionibacterium acnes in response to erythromycin. | 2011 | J. Dermatol. | pmid:21544949 |
Nguyen TT et al. | A food-grade system for inducible gene expression in Lactobacillus plantarum using an alanine racemase-encoding selection marker. | 2011 | J. Agric. Food Chem. | pmid:21504147 |
Gray KL et al. | The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21982562 |
Tilmant K et al. | Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. | 2011 | Toxicol In Vitro | pmid:21515356 |
Sedighi I et al. | Nasal carriage of methicillin resistant Staphylococcus aureus and their antibiotic susceptibility patterns in children attending day-care centers. | 2011 | Acta Microbiol Immunol Hung | pmid:21983324 |
Ma X and Ma S | Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. | 2011 | Curr. Med. Chem. | pmid:21517774 |
Meinertz JR et al. | Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. | 2011 | Bull Environ Contam Toxicol | pmid:21984684 |
Boecxstaens V et al. | Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. | 2011 | Aliment. Pharmacol. Ther. | pmid:21517922 |
Sugawara A et al. | Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21524580 |
Cong C et al. | Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. | 2011 | Eur J Med Chem | pmid:21524827 |
Ando F et al. | Synergic effects of β-estradiol and erythromycin on hERG currents. | 2011 | J. Membr. Biol. | pmid:21484263 |