erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Fritz ME et al. | [The mucocutaneous lymph node syndrome (Kawasaki syndrome). A case with gallbladder hydrops and coronary artery aneurysm]. | 1981 | Schweiz Med Wochenschr | pmid:7233135 |
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Meier B et al. | [Prevention of endocarditis using amoxycillin, clindamycin or erythromycin. Pharmacokinetic observations]. | 1984 | Schweiz Med Wochenschr | pmid:6484553 |
Gartmann J | [Pneumococcal pneumonia: epidemiology, therapy, immunoprophylaxis]. | 1980 | Schweiz Med Wochenschr | pmid:6903401 |
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Lauterburg BH | [Drug damage to the liver: role of reactive metabolites and pharmacokinetics]. | 1985 | Schweiz Med Wochenschr | pmid:3933110 |
Berrettini R | Pertussis (whooping cough). A genie released from the lamp. | 2004 | School Nurse News | pmid:15042972 |
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Holmberg K et al. | Antimicrobial in vitro susceptibility of actinomyces israelii and arachnia propionica. | 1977 | Scand. J. Infect. Dis. | pmid:841278 |
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Krcmery V et al. | Trends in Streptococcus pyogenes resistance to erythromycin in Slovakia: is there a correlation with consumption? | 2002 | Scand. J. Infect. Dis. | pmid:12069033 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
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Bengtsson E et al. | Azidocillin treatment of enterococcal septicemia. | 1972 | Scand. J. Infect. Dis. | pmid:4341815 |
Granström G and Granström M | Effect of erythromycin treatment on antibody responses in pertussis. | 1994 | Scand. J. Infect. Dis. | pmid:7984978 |
Dornbusch K et al. | Antibiotic susceptibility of Clostridium species isolated from human infections. | 1975 | Scand. J. Infect. Dis. | pmid:170668 |
Dornbusch K et al. | Regression line analysis for five antibiotics with strains of Clostridium species. | 1975 | Scand. J. Infect. Dis. | pmid:170669 |
Ringertz S and Kronvall G | Increased use of erythromycin causes resistance in Haemophilus influenzae. | 1987 | Scand. J. Infect. Dis. | pmid:3497435 |
Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
Norinder A et al. | Economic analysis of treatment with roxithromycin in comparison with erythromycin in patients with lower respiratory tract infections. | 1997 | Scand. J. Infect. Dis. | pmid:9112304 |
Kessler HA et al. | Acute pneumococcal epiglottitis in immunocompromised adults. | 1980 | Scand. J. Infect. Dis. | pmid:6933686 |
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Colakoglu S et al. | Prevalence and mechanisms of macrolide resistance in Streptococcus pyogenes in Ankara, Turkey. | 2006 | Scand. J. Infect. Dis. | pmid:16798693 |