erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen C et al. | Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:27709326 |
| Gonser LI et al. | Systemic therapy of ocular and cutaneous rosacea in children. | 2017 | J Eur Acad Dermatol Venereol | pmid:28621909 |
| Szczepanska B et al. | Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. | 2017 | BMC Microbiol. | pmid:28376713 |
| Mingmongkolchai S and Panbangred W | In vitro evaluation of candidate Bacillus spp. for animal feed. | 2017 | J. Gen. Appl. Microbiol. | pmid:28331163 |
| Attaran B et al. | Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. | 2017 | World J. Gastroenterol. | pmid:28275296 |
| Nowakiewicz A et al. | Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). | 2017 | J. Med. Microbiol. | pmid:28260584 |
| Hodge S et al. | Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. | 2017 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:28258107 |
| Lee JH et al. | Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. | 2017 | J. Microbiol. Biotechnol. | pmid:28237994 |
| Descours G et al. | Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. | 2017 | Antimicrob. Agents Chemother. | pmid:28069647 |
| Owen L et al. | A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. | 2017 | Phytother Res | pmid:28124400 |
| Chen K et al. | Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. | 2017 | BMC Infect. Dis. | pmid:28122513 |
| Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
| Wei L et al. | Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. | 2017 | J Environ Sci (China) | pmid:28115128 |
| Koryakina I et al. | Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. | 2017 | ACS Chem. Biol. | pmid:28103677 |
| Sugimoto N et al. | Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. | 2017 | BMC Res Notes | pmid:28057059 |
| Song KH et al. | Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27714592 |
| Kullin B et al. | Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27696234 |
| Pavlović D et al. | Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. | 2017 | Eur J Med Chem | pmid:27657812 |
| Jakubů V et al. | Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. | 2017 | Cent. Eur. J. Public Health | pmid:29346850 |
| Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
| Naimi HM et al. | Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. | 2017 | BMC Infect. Dis. | pmid:29187146 |
| Ricker EB and Nuxoll E | Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. | 2017 | Biofouling | pmid:29039211 |
| Yi M et al. | Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. | 2017 | Arch. Biochem. Biophys. | pmid:28347661 |
| Duelge KJ et al. | An LC-MS/MS method for the determination of antibiotic residues in distillers grains. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28415016 |
| Svetlov MS et al. | Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29229833 |
| Atkinson CT et al. | Expression of acquired macrolide resistance genes in Haemophilus influenzae. | 2017 | J. Antimicrob. Chemother. | pmid:28961896 |
| Wang B et al. | Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. | 2017 | J. Dairy Sci. | pmid:28987584 |
| Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |
| Zhao L et al. | Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. | 2017 | J Sep Sci | pmid:28121061 |
| Stieler AL et al. | Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. | 2016 | Equine Vet. J. | pmid:26174202 |
| Talebi M et al. | Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. | 2016 | PLoS ONE | pmid:28033345 |
| Ray D et al. | Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. | 2016 | BMC Infect. Dis. | pmid:27955635 |
| Murchison L et al. | Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. | 2016 | Pediatr. Surg. Int. | pmid:27655365 |
| Dzyubak E and Yap MN | The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. | 2016 | Antimicrob. Agents Chemother. | pmid:27645242 |
| Abreu AC et al. | Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. | 2016 | Biofouling | pmid:27643487 |
| Jurado-Tarifa E et al. | Genetic diversity and antimicrobial resistance of Campylobacter and Salmonella strains isolated from decoys and raptors. | 2016 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:27638115 |
| Hu Z et al. | Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). | 2016 | Bioresour. Technol. | pmid:27631889 |
| Ghosh S and Banerjee M | Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. | 2016 | Indian J. Med. Res. | pmid:27241651 |
| Pignatello R et al. | Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. | 2016 | Eur J Med Chem | pmid:27236014 |
| Mushtaq A et al. | Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. | 2016 | Antimicrob. Agents Chemother. | pmid:27216060 |
| Hong M et al. | Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. | 2016 | J. Biotechnol. | pmid:27215341 |
| Baek YS et al. | Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. | 2016 | Int. J. Dermatol. | pmid:26892888 |
| Chua SL et al. | Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. | 2016 | Nat Commun | pmid:26892159 |
| Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
| Poliquin V et al. | Preparedness for Implementing Change in Neonatal Ocular Prophylaxis Policies. | 2016 | J Obstet Gynaecol Can | pmid:26872748 |
| Bouvet L et al. | Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series. | 2016 | Anesth. Analg. | pmid:26859878 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Sugawara A et al. | Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model. | 2016 | J. Antibiot. | pmid:26419414 |
| Brunel R and Charpentier X | Trans-translation is essential in the human pathogen Legionella pneumophila. | 2016 | Sci Rep | pmid:27892503 |
| Yuan SF et al. | Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. | 2016 | Water Sci. Technol. | pmid:26901719 |