erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sagkan-Ozturk A et al. | Prokinetics stimulate the increase of ghrelin in mice. | 2016 | Bratisl Lek Listy | pmid:28127970 |
Aslantaş Ö and Demir C | Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. | 2016 | J. Dairy Sci. | pmid:27592437 |
Budha NR et al. | Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. | 2016 | Clin Pharmacokinet | pmid:27225997 |
Wan TW et al. | Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV. | 2016 | PLoS ONE | pmid:27741255 |
Hadjipanayis A et al. | Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. | 2016 | PLoS ONE | pmid:27706247 |
Wu L et al. | Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. | 2016 | PLoS ONE | pmid:27447724 |
Kwon JW | Environmental impact assessment of veterinary drug on fish aquaculture for food safety. | 2016 | Drug Test Anal | pmid:27443211 |
Aslan Bayhan S et al. | Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. | 2016 | Cont Lens Anterior Eye | pmid:27422575 |
Li X et al. | Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. | 2016 | Biomed Res Int | pmid:27413745 |
Ababou A and Koronakis V | Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. | 2016 | PLoS ONE | pmid:27403665 |
Yuan QB et al. | Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. | 2016 | Environ Sci Pollut Res Int | pmid:27384166 |
Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
Sousa M et al. | Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. | 2016 | Microb. Drug Resist. | pmid:26990729 |
Morroni G et al. | Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. | 2016 | Microb. Drug Resist. | pmid:26982016 |
Lenart-Boroń A et al. | Phenotypic and Molecular Antibiotic Resistance Determination of Airborne Coagulase Negative Staphylococcus spp. Strains from Healthcare Facilities in Southern Poland. | 2016 | Microb. Drug Resist. | pmid:26978225 |
Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
Diawara I et al. | Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. | 2016 | Infect. Genet. Evol. | pmid:26961592 |
Barros RR et al. | Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. | 2016 | J. Antimicrob. Chemother. | pmid:27029847 |
Sierra-Arguello YM et al. | Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. | 2016 | Avian Pathol. | pmid:26925976 |
Meng HL et al. | Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis. | 2016 | Biotechnol J | pmid:26709503 |
Gupta P et al. | Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. | 2016 | Nat. Chem. Biol. | pmid:26727240 |
Dréno B | Bacteriological resistance in acne: A call to action. | 2016 | Eur J Dermatol | pmid:26711531 |
Parhizgari N et al. | High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. | 2016 | APMIS | pmid:26709106 |
Li J et al. | Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. | 2016 | Nutr Clin Pract | pmid:26459161 |
Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
Feuillolay C et al. | A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris. | 2016 | Phytomedicine | pmid:26969384 |
Naik KM and Nandibewoor ST | Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. | 2016 | Luminescence | pmid:26239839 |
Huang M et al. | Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26223917 |
Schneider SC et al. | Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. | 2015 | Antimicrob. Agents Chemother. | pmid:26195516 |
Takagi M et al. | Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | 2015 | Drug Metab. Pharmacokinet. | pmid:26195223 |
Aydin S et al. | Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. | 2015 | Water Res. | pmid:26188597 |
Fayed B et al. | Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. | 2015 | Appl. Environ. Microbiol. | pmid:26431970 |
Pesola AK et al. | Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. | 2015 | Euro Surveill. | pmid:25990232 |
Sun XJ et al. | Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25957293 |
Guo MT et al. | Insights into the amplification of bacterial resistance to erythromycin in activated sludge. | 2015 | Chemosphere | pmid:25957255 |
Ikebe T et al. | Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. | 2015 | Epidemiol. Infect. | pmid:25703404 |
Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
Choi JH et al. | Distribution of emm types among group A Streptococcus isolates from children in Korea. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25700867 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Sessa R et al. | Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. | 2015 | Biomed Res Int | pmid:25685793 |
Wan J et al. | Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. | 2015 | J. Hazard. Mater. | pmid:25464321 |
Zhou Z et al. | Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. | 2015 | Antimicrob. Agents Chemother. | pmid:25451048 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
Haxel BR et al. | Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. | 2015 | Laryngoscope | pmid:25425539 |
Llorca M et al. | Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. | 2015 | Chemosphere | pmid:24972175 |
Mazur CS et al. | P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. | 2015 | Toxicol. Lett. | pmid:25268938 |
Cochrane SA et al. | Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. | 2015 | J. Med. Chem. | pmid:26636619 |
Wilson DW et al. | Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. | 2015 | BMC Biol. | pmid:26187647 |
Chazan B et al. | Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. | 2015 | Microb. Drug Resist. | pmid:26430943 |
Hoffmann K et al. | Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. | 2015 | BMC Infect. Dis. | pmid:25981559 |