erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
Shim J et al. | Clinical inquiry: what is the best treatment for impetigo ? | 2014 | J Fam Pract | pmid:25061625 |
Krishnappa LG et al. | Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. | 2014 | Acta Microbiol Immunol Hung | pmid:24939685 |
Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
Caierão J et al. | Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. | 2014 | PLoS ONE | pmid:25356595 |
Wyatt TA et al. | cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25150062 |
Abarzúa F et al. | [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at ClÃnica Alemana Temuco, Southern Chile]. | 2014 | Rev Chilena Infectol | pmid:25146205 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Johansson M et al. | Sequence-dependent elongation dynamics on macrolide-bound ribosomes. | 2014 | Cell Rep | pmid:24836000 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
Boomkamp SD et al. | Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. | 2014 | Br. J. Pharmacol. | pmid:24467222 |
Jun BY et al. | Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. | 2014 | Surg Endosc | pmid:24380989 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Kuwahara T et al. | Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. | 2013 | J. Cardiovasc. Electrophysiol. | pmid:23551640 |
Lozada LE et al. | Development of pyloric stenosis after a 4-day course of oral erythromycin. | 2013 | Pediatr Emerg Care | pmid:23558266 |
Cuello-GarcÃa CA et al. | Treating BCG-induced disease in children. | 2013 | Cochrane Database Syst Rev | pmid:23440826 |
Jersild Jespersen M et al. | [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. | 2013 | Ugeskr. Laeg. | pmid:23462037 |
Sugino K et al. | Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. | 2013 | Intern. Med. | pmid:24292765 |
Goh S et al. | Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. | 2013 | MBio | pmid:24255122 |
Li YY et al. | Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. | 2013 | BMC Genomics | pmid:23902230 |
Cai G et al. | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | 2013 | J. Nat. Prod. | pmid:24224794 |
Ansari NN et al. | Treatment of chronic rhinosinusitis using erythromycin phonophoresis. | 2013 | Physiother Theory Pract | pmid:22891948 |
Fang J et al. | Dissecting the function of a protruding loop in AcrB trimerization. | 2013 | J. Biomol. Struct. Dyn. | pmid:22877148 |
Chen DK et al. | [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24548451 |
Opdam FL et al. | Breath tests to phenotype drug disposition in oncology. | 2013 | Clin Pharmacokinet | pmid:23868281 |
James GD et al. | Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. | 2013 | Prim Care Respir J | pmid:23839240 |
Parhi AK et al. | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23891185 |
Lee A | Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? | 2013 | J. Gastrointest. Surg. | pmid:23801519 |
Liu ZX et al. | [Inhibition of methanogenium by erythromycin and its domestation]. | 2013 | Huan Jing Ke Xue | pmid:23798140 |
Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
Wittwer MB et al. | Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. | 2013 | J. Med. Chem. | pmid:23241029 |
Sánchez Valenzuela A et al. | Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. | 2013 | Foodborne Pathog. Dis. | pmid:23259502 |
Sanad YM et al. | Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. | 2013 | Foodborne Pathog. Dis. | pmid:23259503 |
Haruna M et al. | Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. | 2013 | J. Vet. Med. Sci. | pmid:23220905 |
Javid FA et al. | Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. | 2013 | Eur. J. Pharmacol. | pmid:23201066 |
Goodman CD et al. | Chemobiosynthesis of new antimalarial macrolides. | 2013 | Antimicrob. Agents Chemother. | pmid:23208707 |
Metzler K et al. | Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. | 2013 | J. Antimicrob. Chemother. | pmid:23169894 |
Rogers GB et al. | Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. | 2013 | Thorax | pmid:23564400 |