erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Dzyubak E and Yap MN | The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. | 2016 | Antimicrob. Agents Chemother. | pmid:27645242 |
Abreu AC et al. | Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. | 2016 | Biofouling | pmid:27643487 |
Pignatello R et al. | Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. | 2016 | Eur J Med Chem | pmid:27236014 |
Mushtaq A et al. | Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. | 2016 | Antimicrob. Agents Chemother. | pmid:27216060 |
Baek YS et al. | Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. | 2016 | Int. J. Dermatol. | pmid:26892888 |
Chua SL et al. | Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. | 2016 | Nat Commun | pmid:26892159 |
Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
Brunel R and Charpentier X | Trans-translation is essential in the human pathogen Legionella pneumophila. | 2016 | Sci Rep | pmid:27892503 |
Yuan SF et al. | Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. | 2016 | Water Sci. Technol. | pmid:26901719 |