erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Angiomatosis D000798 1 associated lipids
Animal Diseases D000820 2 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Spider Bites D001098 1 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Asthenia D001247 5 associated lipids
Ataxia D001259 20 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Balanitis D001446 4 associated lipids
Bartonella Infections D001474 3 associated lipids
Bile Reflux D001655 2 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blepharitis D001762 4 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Bone Resorption D001862 7 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bradycardia D001919 13 associated lipids
Bronchiectasis D001987 7 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchopneumonia D001996 7 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Bursitis D002062 3 associated lipids
Campylobacter Infections D002169 13 associated lipids
Carbuncle D002270 1 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Thomas L et al. Ophthalmic Considerations in Stevens-Johnson Syndrome. 2016 J. Pediatr. pmid:27318376
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Tang C et al. The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. 2016 Sci Rep pmid:27897206
Sun H et al. Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. 2016 Sci Rep pmid:27644411
Tack J et al. Motilin-induced gastric contractions signal hunger in man. 2016 Gut pmid:25539673
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
Hu P et al. Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. 2016 Turk J Gastroenterol pmid:27782898
Heß S and Gallert C Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. 2016 Microb. Ecol. pmid:27220972
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
Caumes E et al. [Donovanosis (granuloma inguinale)]. 2016 Ann Dermatol Venereol pmid:27773509
DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Metcalf BJ et al. Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. 2016 Clin. Microbiol. Infect. pmid:27542334
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Hua CZ et al. [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. 2016 Zhonghua Er Ke Za Zhi pmid:27510868
Johanesen P and Lyras D Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. 2016 Methods Mol. Biol. pmid:27507343
Barbanti F et al. Transfer of Clostridium difficile Genetic Elements Conferring Resistance to Macrolide-Lincosamide-Streptogramin B (MLSB) Antibiotics. 2016 Methods Mol. Biol. pmid:27507342
Gaglio R et al. Evaluation of antimicrobial resistance and virulence of enterococci from equipment surfaces, raw materials, and traditional cheeses. 2016 Int. J. Food Microbiol. pmid:27467501
Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Del Grosso M et al. ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. 2016 Antimicrob. Agents Chemother. pmid:27067338
Aydin S Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. 2016 Appl. Microbiol. Biotechnol. pmid:27033714
Shi HY et al. [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. 2016 Zhonghua Yi Xue Za Zhi pmid:27760665
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Baker KR et al. A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. 2016 Antimicrob. Agents Chemother. pmid:27458225
Juda M et al. The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. 2016 Mem. Inst. Oswaldo Cruz pmid:27008373
Cui B et al. Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. 2016 Mol. Genet. Genomics pmid:27000656
Lewis K et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. 2016 Crit Care pmid:27527069
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
He HJ et al. Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. 2016 J Microbiol Immunol Infect pmid:24768213
Bhadra PK et al. Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. 2016 Org. Biomol. Chem. pmid:27273525
Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
Prabhasankar VP et al. Removal rates of antibiotics in four sewage treatment plants in South India. 2016 Environ Sci Pollut Res Int pmid:26797959
Seefeldt AC et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. 2016 Nucleic Acids Res. pmid:26792896
Li M et al. Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity. 2016 Pharm. Res. pmid:26792570
Lapierre L et al. Characterization of Antimicrobial Susceptibility and Its Association with Virulence Genes Related to Adherence, Invasion, and Cytotoxicity in Campylobacter jejuni and Campylobacter coli Isolates from Animals, Meat, and Humans. 2016 Microb. Drug Resist. pmid:26779841
Pan M and Chu LM Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. 2016 Ecotoxicol. Environ. Saf. pmid:26773832
Rodrigues S et al. Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. 2016 Sci. Total Environ. pmid:26760278
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Maye S et al. Transformation of serum-susceptible Escherichia coli O111 with p16Slux plasmid to allow for real-time monitoring of complement-based inactivation of bacterial growth in bovine milk. 2016 J. Dairy Sci. pmid:26585477
Nenquin M and Henquin JC Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. 2016 Diabetes Obes Metab pmid:26584950
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Wu H et al. In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. 2016 Appl. Microbiol. Biotechnol. pmid:26552796
Berg L et al. [Cutaneous diphtheria after a minor injury in Sri Lanka]. 2016 Hautarzt pmid:26525966
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753
Boetsch C et al. Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. 2016 Clin Pharmacokinet pmid:26341813
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
Snoeys J et al. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Clin. Pharmacol. Ther. pmid:26259716