erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Superinfection D015163 3 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Bites, Human D001734 2 associated lipids
Dacryocystitis D003607 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Rickettsia Infections D012282 5 associated lipids
Spider Bites D001098 1 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Sporotrichosis D013174 3 associated lipids
Ehrlichiosis D016873 2 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Rubella D012409 2 associated lipids
Pleural Diseases D010995 4 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Thomas L et al. Ophthalmic Considerations in Stevens-Johnson Syndrome. 2016 J. Pediatr. pmid:27318376
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Tang C et al. The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. 2016 Sci Rep pmid:27897206
Tack J et al. Motilin-induced gastric contractions signal hunger in man. 2016 Gut pmid:25539673
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
Hu P et al. Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. 2016 Turk J Gastroenterol pmid:27782898
Heß S and Gallert C Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. 2016 Microb. Ecol. pmid:27220972
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
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Johanesen P and Lyras D Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. 2016 Methods Mol. Biol. pmid:27507343
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Gaglio R et al. Evaluation of antimicrobial resistance and virulence of enterococci from equipment surfaces, raw materials, and traditional cheeses. 2016 Int. J. Food Microbiol. pmid:27467501
Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Del Grosso M et al. ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. 2016 Antimicrob. Agents Chemother. pmid:27067338
Aydin S Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. 2016 Appl. Microbiol. Biotechnol. pmid:27033714
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Baker KR et al. A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. 2016 Antimicrob. Agents Chemother. pmid:27458225
Juda M et al. The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. 2016 Mem. Inst. Oswaldo Cruz pmid:27008373
Lewis K et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. 2016 Crit Care pmid:27527069
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
He HJ et al. Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. 2016 J Microbiol Immunol Infect pmid:24768213
Bhadra PK et al. Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. 2016 Org. Biomol. Chem. pmid:27273525
Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
Pan M and Chu LM Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. 2016 Ecotoxicol. Environ. Saf. pmid:26773832
Rodrigues S et al. Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. 2016 Sci. Total Environ. pmid:26760278
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Berg L et al. [Cutaneous diphtheria after a minor injury in Sri Lanka]. 2016 Hautarzt pmid:26525966
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
Snoeys J et al. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Clin. Pharmacol. Ther. pmid:26259716
Chen C et al. Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:27709326
Sato T et al. Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. 2017 Microbiol. Immunol. pmid:28504455
Wozniak A et al. Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. 2017 J. Med. Microbiol. pmid:28463664
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Ge LL et al. [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. 2017 Zhonghua Er Ke Za Zhi pmid:28173648
Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Wang Y et al. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. 2017 Bioorg. Med. Chem. Lett. pmid:28129976
Owen L et al. A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. 2017 Phytother Res pmid:28124400
Chen K et al. Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. 2017 BMC Infect. Dis. pmid:28122513
Berni E et al. Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. 2017 BMJ Open pmid:28115334
Kassem II et al. Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. 2017 Foodborne Pathog. Dis. pmid:27768387
Song KH et al. Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27714592
Austin BA and Fleischer AB The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. 2017 J Dermatolog Treat pmid:27425633
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Yi M et al. Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. 2017 Arch. Biochem. Biophys. pmid:28347661
Duelge KJ et al. An LC-MS/MS method for the determination of antibiotic residues in distillers grains. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28415016
Svetlov MS et al. Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229833
Michael-Kordatou I et al. On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. 2017 J. Hazard. Mater. pmid:26947803