erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Palmieri C et al. | Interspecies mobilization of an ermT-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. | 2013 | J. Antimicrob. Chemother. | pmid:22949621 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Wasels F et al. | Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. | 2013 | J. Med. Microbiol. | pmid:23741023 |
Kawai Y et al. | Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23716043 |
Yun SH et al. | Demodex folliculitis presenting as periocular vesiculopustular rash. | 2013 | Orbit | pmid:23895342 |
González-Hein G et al. | [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. | 2013 | Rev Chilena Infectol | pmid:23677151 |
Adhikari MD et al. | Membrane-directed high bactericidal activity of (gold nanoparticle)-polythiophene composite for niche applications against pathogenic bacteria. | 2013 | Adv Healthc Mater | pmid:23184755 |
Utsunomiya S et al. | Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. | 2013 | Regul. Pept. | pmid:23142315 |
Li YJ et al. | EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. | 2013 | Pulm Pharmacol Ther | pmid:23291319 |
Jiang M et al. | Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. | 2013 | Metab. Eng. | pmid:24060454 |
Gold RM and Lawhon SD | Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. | 2013 | J. Clin. Microbiol. | pmid:24025915 |
Henson AM et al. | Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. | 2013 | J. Clin. Microbiol. | pmid:24048538 |
Wieczorek K et al. | Prevalence and antimicrobial resistance of Campylobacter spp. isolated from poultry carcasses in Poland. | 2013 | J. Food Prot. | pmid:23905805 |
Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
Pohl O et al. | Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. | 2013 | J Clin Pharm Ther | pmid:24102384 |
Desroy N et al. | Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. | 2013 | J. Med. Chem. | pmid:23409840 |
Magee TV et al. | Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23414806 |
Lermite E et al. | Complications after pancreatic resection: diagnosis, prevention and management. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23415988 |
Atamanyuk D et al. | Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. | 2013 | J. Med. Chem. | pmid:23445125 |
Gomes DL et al. | SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. | 2013 | J. Med. Microbiol. | pmid:23449875 |
Yang M et al. | Macrolides for diffuse panbronchiolitis. | 2013 | Cochrane Database Syst Rev | pmid:23450579 |
Schafer F et al. | Antimicrobial susceptibility and genetic characteristics of Propionibacterium acnes isolated from patients with acne. | 2013 | Int. J. Dermatol. | pmid:23432195 |
Chen Y et al. | Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. | 2013 | Bioresour. Technol. | pmid:23500575 |
Capanna F et al. | Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. | 2013 | Swiss Med Wkly | pmid:23572445 |
Yadav DK et al. | Failure of secondary prophylaxis with erythromycin in rheumatic heart disease. | 2013 | Indian Pediatr | pmid:24382905 |
Chen Y et al. | Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. | 2013 | Bioprocess Biosyst Eng | pmid:23361182 |
Melnik BC and Schmitz G | Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? | 2013 | Exp. Dermatol. | pmid:23800068 |
Müller M et al. | The absolute configuration of (+)- and (-)-erythro-mefloquine. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23616269 |
Gaudreau C et al. | Campylobacter coli outbreak in men who have sex with men, Quebec, Canada, 2010-2011. | 2013 | Emerging Infect. Dis. | pmid:23647786 |
Kjær S et al. | Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. | 2013 | Dan Med J | pmid:23651712 |
Ragazzi E et al. | Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. | 2013 | J Chemother | pmid:23684362 |
Rasamiravaka T et al. | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. | 2013 | J Infect Dev Ctries | pmid:23592641 |
Nakajima T et al. | Absence of intervening sequences and point mutations in the V domain within 23S rRNA in Campylobacter lari isolates. | 2013 | Folia Microbiol. (Praha) | pmid:23595231 |
Ma X et al. | Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children. | 2013 | Chin. Med. J. | pmid:23595388 |
Hinarejos P et al. | The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. | 2013 | J Bone Joint Surg Am | pmid:23636182 |
Gao X et al. | Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. | 2013 | J. Am. Chem. Soc. | pmid:23464668 |
Roberts DW | What is the role of antibiotic-containing cement in total knee arthroplasty? | 2013 | J Bone Joint Surg Am | pmid:23636201 |
Simoens S et al. | Preventing COPD exacerbations with macrolides: a review and budget impact analysis. | 2013 | Respir Med | pmid:23352223 |
Lim CH et al. | Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. | 2013 | World J. Gastroenterol. | pmid:23885150 |
Jiang M et al. | The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. | 2013 | J Vis Exp | pmid:23354010 |
Elens L et al. | CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. | 2013 | Pharmacogenomics | pmid:23327575 |
Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
Lins RX et al. | Antimicrobial resistance and virulence traits of Enterococcus faecalis from primary endodontic infections. | 2013 | J Dent | pmid:23851130 |
Gonçalves A et al. | Antimicrobial resistance in faecal enterococci and Escherichia coli isolates recovered from Iberian wolf. | 2013 | Lett. Appl. Microbiol. | pmid:23336611 |
Rożynek E et al. | Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. | 2013 | Foodborne Pathog. Dis. | pmid:23638847 |
Grabowicz M et al. | Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. | 2013 | J. Bacteriol. | pmid:23316047 |
Dubey D et al. | A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. | 2013 | Asian Pac J Trop Biomed | pmid:23593595 |
Marcellin E et al. | Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. | 2013 | BMC Genomics | pmid:23324121 |
Cui B et al. | Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. | 2013 | J. Clin. Microbiol. | pmid:23052315 |
Baltar F et al. | Bacterial versus archaeal origin of extracellular enzymatic activity in the Northeast Atlantic deep waters. | 2013 | Microb. Ecol. | pmid:23015014 |