erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gumaste VV | Erythromycin-induced pancreatitis. | 1989 | Am. J. Med. | pmid:2729328 |
Klein JO | Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. | 1985 | Am. J. Med. | pmid:4014286 |
Rudin JE et al. | Failure of erythromycin in treatment of Legionella micdadei pneumonia. | 1984 | Am. J. Med. | pmid:6607673 |
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Dark D | Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. | 1991 | Am. J. Med. | pmid:1656740 |
Mallory SB | Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. | 1991 | Am. J. Med. | pmid:1656741 |
Hopkins S | Clinical toleration and safety of azithromycin. | 1991 | Am. J. Med. | pmid:1656742 |
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Schentag JJ and Ballow CH | Tissue-directed pharmacokinetics. | 1991 | Am. J. Med. | pmid:1656743 |
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ROBINSON MM | Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate. | 1962 | Am. J. Med. Sci. | pmid:14492926 |
Devasia RA et al. | Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. | 2009 | Am. J. Med. Sci. | pmid:19301451 |
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Holoshitz J et al. | Listeria monocytogenes pericarditis in a chronically hemodialyzed patient. | 1984 Jul-Aug | Am. J. Med. Sci. | pmid:6465192 |
Feigin RD et al. | Treatment of penicillin-resistant staphylococcal infections with clindamycin. | 1971 | Am. J. Med. Sci. | pmid:5578775 |
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RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
HIRSCH HA et al. | Effect of food on absorption of a new form of erythromycin propionate. | 1960 | Am. J. Med. Sci. | pmid:14401969 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
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CLAPPER WE et al. | THE SUSCEPTIBILITY OF CERTAIN BACTERIA TO LINCOMYCIN AS RELATED TO ATTAINABLE SERUM LEVELS IN HUMAN ADULTS. | 1964 | Am. J. Med. Sci. | pmid:14130319 |
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Gray BM | Case report: Rhodococcus equi pneumonia in a patient infected by the human immunodeficiency virus. | 1992 | Am. J. Med. Sci. | pmid:1595781 |
Rao KV and Ralston RA | Meningitis due to Campylobacter fetus intestinalis in a kidney transplant recipient. A case report. | 1987 | Am. J. Nephrol. | pmid:3324765 |
KIEFER L et al. | The placental transfer of erythomycin. | 1955 | Am. J. Obstet. Gynecol. | pmid:13218094 |
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Eschenbach DA et al. | A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery. The Vaginal Infections and Prematurity Study Group. | 1991 | Am. J. Obstet. Gynecol. | pmid:2003533 |
Quinn PA et al. | Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. | 1983 | Am. J. Obstet. Gynecol. | pmid:6849358 |