erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Katrush VR and Zhukovskaia SA | [Separation of emulsions during extraction of antibiotics from native solutions]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:3606053 |
Tsirkin RS | [Antibiotic sensitivity of staphylococci associated with adenoviruses]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:3923916 |
Kuznetsov LE | [Effect of a temperature regimen on erythromycin biosynthesis]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:4051468 |
Efimova OG et al. | [Electron microscopic study of the interaction of cultures of Bordetella pertussis altered by antibiotic action with a human amniotic cell culture]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:2878640 |
Gusakova GV et al. | [IR spectral research on erythromycin mono- and dihydrates]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3777893 |
Gusakova GV et al. | [Infrared spectra and the molecular conformations of macrolide-group antibiotics in solution]. | 1986 | Antibiot. Med. Biotekhnol. | pmid:3777894 |
Zurabyan VA et al. | [In vitro influence of biologically active factors of microorganisms on antibiotic susceptibility of Yersinia pestis]. | 1997 | Antibiot. Khimioter. | pmid:9463297 |
Sadovnikova SF and Selina EV | [Five years of sumamed on Russian market]. | 1997 | Antibiot. Khimioter. | pmid:9463300 |
Ukhabotina LS et al. | [Cloning of clusters of erythromycin biosynthesis genes of Streptomyces erythraeus (Saccharopolyspora erythraea)]. | 1990 | Antibiot. Khimioter. | pmid:2150305 |
Sytnik SI | [Antibiotic sensitivity of Staphylococci populating the breast skin of nursing women]. | 1989 | Antibiot. Khimioter. | pmid:2730223 |
Bulgakova VG et al. | [Metabolism of alpha-ketoacids in erythromycin biosynthesis in various strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166559 |
Kirichenko VN et al. | [Use of protoplast fusion in the selection of erythromycin-producing strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166562 |
Strachynskił LS et al. | [Pharmacoepidemiology of antibiotics in the treatment of respiratory tract infections in pediatric outpatients]. | 1997 | Antibiot. Khimioter. | pmid:9412396 |
Nastasyak IN | [Localization of rifampicin resistance determinants on genetic map of Saccharopolyspora erythraea]. | 1997 | Antibiot. Khimioter. | pmid:9412406 |
Zavorotnaia SA et al. | [Genetic instability of the feature of streptomycin resistance in Streptomyces erythraeus]. | 1990 | Antibiot. Khimioter. | pmid:2078071 |
StrachunskiÄ LS et al. | [Comparative clinical effectiveness and tolerance of azithromycin (sumamed) and erythromycin in patients with sinusitis]. | 1993 | Antibiot. Khimioter. | pmid:8060176 |
Shubin SV et al. | [Effectiveness of azithromycin relative to chlamydia infection in reactive arthritis]. | 1993 | Antibiot. Khimioter. | pmid:8060177 |
Kirichenko NV et al. | [Isolation and characterization of genetic recombinants in protoplast fusion in Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8060179 |
Fomina IP et al. | [Azithromycin (sumamed)--in the treatment of respiratory tract infections]. | 1996 | Antibiot. Khimioter. | pmid:8929121 |
Ukhabotina LS et al. | [Identification and characteristics of plasmids of the strains of erythromycin-producing Streptomyces erythreus]. | 1988 | Antibiot. Khimioter. | pmid:2837155 |
Sazykin IuO | [Modern macrolides and azalides in the therapy of infectious-inflammatory diseases. A seminar, February 1994, Moscow]. | 1994 Feb-Mar | Antibiot. Khimioter. | pmid:7979801 |
Lialikov SA et al. | [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. | 2012 | Antibiot. Khimioter. | pmid:23700934 |
Kolpakov AI et al. | [Use of exogenous ribonuclease for improvement of Lactobacillus biological properties]. | 1998 | Antibiot. Khimioter. | pmid:9791680 |
Platonova MM et al. | [Clinical significance of fungal and microbial associations and antibacterial therapy for treatment of chronic inflammatory respiratory tract diseases in children]. | 1998 | Antibiot. Khimioter. | pmid:9791682 |
Oriabinskaia LB et al. | [Energy metabolism in Staphylococci containing plasmids of resistance to a number of antibiotics]. | 1992 | Antibiot. Khimioter. | pmid:1296533 |
Grigor'ev AE et al. | [Construction of hybrid plasmids containing genes for erythromycin biosynthesis and amplifying sequence AUD-Sr1 of Streptomyces rimosus]. | 1992 | Antibiot. Khimioter. | pmid:1296539 |
Kurmanova KB et al. | [Efficacy of pefloxacin in the treatment of complicated relapsing erysipelas]. | 1997 | Antibiot. Khimioter. | pmid:9480650 |
Gagaeva EV and Firsov AA | [Pharmacokinetics of protegentin, a combined preparation]. | 1991 | Antibiot. Khimioter. | pmid:1953168 |
Arzumanian OG et al. | [Effect of partial pressure of solute oxygen on the intensity of respiration of cultures of antibiotic producers]. | 1990 | Antibiot. Khimioter. | pmid:2334239 |
Zakharova GM et al. | [Study of the effect of protoplast formation on the antibiotic activity of erythromycin producers]. | 1990 | Antibiot. Khimioter. | pmid:2334241 |
Grudinina SA et al. | [Dynamics of Streptococcos pneumoniae antibiotic resistance extension in Moscow in 1998-2003]. | 2004 | Antibiot. Khimioter. | pmid:15460020 |
Navashin SM and Nikitin AV | [New macrolide antibiotics, rifamycins and peptide antibiotics discussed at the 27th International Conference on Antimicrobial Agents and Chemotherapy]. | 1991 | Antibiot. Khimioter. | pmid:1850977 |
Nazarov AD et al. | [Erythromycin pharmacokinetics in children after rectal and oral administration]. | 1991 | Antibiot. Khimioter. | pmid:2025118 |
Korenev SV et al. | [Pharmacological availability of erythromycin granules for children's use]. | 1990 | Antibiot. Khimioter. | pmid:2264745 |
Bryzgalova TE et al. | [Conditions for immobilizing Streptomyces erythreus in a calcium alginate gel and the apparatus setup for the process]. | 1988 | Antibiot. Khimioter. | pmid:3288145 |
Vasilos LV et al. | [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. | 1995 | Antibiot. Khimioter. | pmid:8593094 |
BureÄko SF et al. | [Various properties of erythromycin basicity]. | 1992 | Antibiot. Khimioter. | pmid:1514846 |
Dolgova GV et al. | [Experimental study of a novel formulation for local application based on gentamicin, erythromycin and protease C]. | 1990 | Antibiot. Khimioter. | pmid:2275587 |
Nigmatulin AZ et al. | [Antibiotic binding by leukocytes from brucellosis patients]. | 1990 | Antibiot. Khimioter. | pmid:2275592 |
Kotova NV | [Kinetic and equilibrium parameters of erythromycin sorption on various sorbents]. | 2009 | Antibiot. Khimioter. | pmid:20583559 |
Belousov IuB et al. | [Dirithromycin in the treatment of infections of the lower respiratory tract]. | 1995 | Antibiot. Khimioter. | pmid:8645058 |
Minaeva NZ et al. | [Bacteria of the genus Arcobacter, a new etiological factor of nosocomial infections]. | 2006 | Antibiot. Khimioter. | pmid:16878388 |
Gurevich KG et al. | [Comparative pharmacokinetics of erythromycin target cell-associated transport and intravenous administration in patients with pneumonia]. | 2006 | Antibiot. Khimioter. | pmid:18030786 |
Motina GL et al. | [Effect of the methods of sterilization on the quality of nutrient media and on the level of antibiotic production]. | 1991 | Antibiot. Khimioter. | pmid:1814272 |
Michurina TA et al. | [Antioxidant effect on the growth of Saccharopolyspora erythraea and biosynthesis of erythromycins]. | 2005 | Antibiot. Khimioter. | pmid:19140479 |
Petrova MS et al. | [Antibiotic therapy in children with pertussis]. | 1992 | Antibiot. Khimioter. | pmid:1300936 |
Berezhinskaia VV and Dolgova GV | [Macrolide antibiotics and their use in combined pharmacotherapy]. | 1989 | Antibiot. Khimioter. | pmid:2686571 |
Sereda EV et al. | [Use of oral macrolide and azalide antibiotics in children with bronchopulmonary diseases]. | 1994 | Antibiot. Khimioter. | pmid:7840711 |
Sazykin IuO et al. | [Ketolides--erythromycin derivatives with activity against macrolide-resistant bacteria]. | 2000 | Antibiot. Khimioter. | pmid:10707799 |
MashkilleÄson AL | [Azithromycin in the treatment of syphilis]. | 1994 | Antibiot. Khimioter. | pmid:7848005 |
Guchev IA et al. | [Efficacy and safety of azithromycin prophylaxis of respiratory tract infections in military community]. | 2004 | Antibiot. Khimioter. | pmid:15727144 |
Fomina IP | [Second international conference on macrolides, azalides and streptogramins (Venice, Italy, January 19-22, 1994)]. | 1994 | Antibiot. Khimioter. | pmid:7914722 |
Pozdniakova VP et al. | [Protegentin--a combined preparation for the local treatment of suppurative infection]. | 1993 Oct-Nov | Antibiot. Khimioter. | pmid:8085892 |
WILLIAMSON GM and ZINNEMANN K | The susceptibility of coliform bacilli to erythromycin. | 1962 | Antibiot Chemother (Northfield) | pmid:14007243 |
KIRBY WM et al. | Erythromycin serum concentrations following administration in acid-resistant tablets. | 1953 | Antibiot Chemother (Northfield) | pmid:24542409 |
KIRSHBAUM A et al. | A cupplate method for the determination of erythromycin concentrations in serum and other body fluids. | 1953 | Antibiot Chemother (Northfield) | pmid:24542421 |
CLARK RK | The chemistry of erythromycin. I. Acid degradation products. | 1953 | Antibiot Chemother (Northfield) | pmid:24542535 |
MAPLE FM et al. | Serum concentrations of erythromycin following intravenous administration. | 1953 | Antibiot Chemother (Northfield) | pmid:24542586 |
LEE CC et al. | Tissue distribution of erythromycin in rats. | 1953 | Antibiot Chemother (Northfield) | pmid:24542649 |
SYLVESTER JC and JOSSELYN LE | Absorption of erythromycin. II. Erythromycin stearate. | 1953 | Antibiot Chemother (Northfield) | pmid:24542651 |
GRIGSBY ME et al. | Some laboratory and clinical experiences with erythromycin. | 1953 | Antibiot Chemother (Northfield) | pmid:24542704 |
HASBROUCK RB and GARVEN FC | The chemistry of erythromycin. II. Acid degradation products. | 1953 | Antibiot Chemother (Northfield) | pmid:24542706 |
ANDERSON EA | Cure of resistant meningococcemia with erythromycin. | 1953 | Antibiot Chemother (Northfield) | pmid:24542853 |
HAIGHT TH et al. | Erythromycin therapy of respiratory infections. II. Effects of varying durations of therapy of streptococcal infections on eradication of streptococci and on formation of antistreptolysin O. | 1954 | Antibiot Chemother (Northfield) | pmid:24543018 |
LAING CR and SCOTT RB | Erythromycin-polymyxin ointment in the treatment of pyoderma in children. | 1954 | Antibiot Chemother (Northfield) | pmid:24543095 |
TUNEVALL G and HEDENIUS P | Laboratory and clinical studies with erythromycin. | 1954 | Antibiot Chemother (Northfield) | pmid:24543103 |
LEE CC et al. | Site of absorption of erythromycin in rats. | 1954 | Antibiot Chemother (Northfield) | pmid:24543219 |
MANTEN A | Synergism and antagonism between antibiotic mixtures containing erythromycin. | 1954 | Antibiot Chemother (Northfield) | pmid:24543317 |
KUZEL NR et al. | Spectrophotometric determination of erythromycin in pharmaceutical products. | 1954 | Antibiot Chemother (Northfield) | pmid:24543318 |
CLARK RK and TATERKA M | The chemistry of erythromycin. III. Acid degradation products of erythromycin B. | 1955 | Antibiot Chemother (Northfield) | pmid:24543468 |
CLARK RK and FREIFELDER M | The synthesis of new erythromycins. | 1957 | Antibiot Chemother (Northfield) | pmid:24544531 |
LEE CC et al. | Further pharmacological studies on propionyl erythromycin ester lauryl sulfate. | 1961 | Antibiot Chemother (Northfield) | pmid:13760219 |
CLARK RK and VARNER EL | New esters of erythromycin. | 1957 | Antibiot Chemother (Northfield) | pmid:24544532 |
MANIAR AC et al. | A comparison of the in vitro and in vivo activity of erythromycin and spiramycin. | 1960 | Antibiot Chemother (Northfield) | pmid:13766168 |
ROBINSON MM | Demonstration by "challenge" of hepatic dysfunction associated with propionyl erythromycin ester lauryl sulfate. | 1962 | Antibiot Chemother (Northfield) | pmid:14492925 |
GRIFFITH RS and BLACK HR | A comparison of blood levels after oral administration of erythromycin and erythromycin estolate. | 1962 | Antibiot Chemother (Northfield) | pmid:13901859 |
GRIFFITH RS and BLACK HR | Comparison of antimicrobial activity of erythromycin estolate and demethylchlortetracycline against hemolytic streptococci. | 1962 | Antibiot Chemother (Northfield) | pmid:13901860 |
GRIFFITH RS | The ratio of antimicrobial activity between propionyl erythromycin lauryl sulfate and erythromycin ethyl carbonate. | 1961 | Antibiot Chemother (Northfield) | pmid:13901862 |
GROGAN JB et al. | Antibiotic susceptibility of phage type 80/81 strains of staphylococci isolated from hospital and community populations. | 1962 | Antibiot Chemother (Northfield) | pmid:13902091 |
CORDERO FA | Propionyl erythromycin ester lauryl sulfate in the treatment of treponematosis and chancroid. | 1961 | Antibiot Chemother (Northfield) | pmid:13881298 |
STROM J | Penicillin and erythromycin singly and in combination in scarlatina therapy and the interference between them. | 1961 | Antibiot Chemother (Northfield) | pmid:13917845 |
LIMSON BM | Lauryl sulfate salt of propionyl erythromycin: antibacterial activity in serum and therapeutic evaluation of low doses. | 1961 | Antibiot Chemother (Northfield) | pmid:14465340 |
SALDANA TATE L | In vivo and in vitro evaluation of oleandomycin, erythromycin, and tetracycline against cultures of Staphylococcus aureus. | 1960 | Antibiot Chemother (Northfield) | pmid:14440930 |
SCHNEIERSON SS et al. | Inhibition of Pseudomonas aeruginosa pigment formation by chloramphenicol and erythromycin. | 1960 | Antibiot Chemother (Northfield) | pmid:14443279 |
Schmid EE | The macrolide group of antibiotics. Mode of action. | 1971 | Antibiot Chemother (1971) | pmid:4951002 |
Connamacher RH | Inducible bacterial resistance. | 1975 | Antibiot Chemother (1971) | pmid:773276 |
Wilson JT and van Boxtel CJ | Pharmacokinetics of Erythromycin in man. | 1978 | Antibiot Chemother (1971) | pmid:27136 |
Tanimoto H | A review of the recent progress in treatment of patients with diffuse panbronchiolitis associated with Pseudomonas aeruginosa infection in Japan. | 1991 | Antibiot Chemother (1971) | pmid:1801651 |
FORFAR JO and MACCABE AF | Erythromycin--a review. | 1957 | Antibiot Chemother | pmid:13488431 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
FOX RT et al. | Clinical and laboratory experiences with erythromycin in treatment of thoracic empyema. | 1955-1956 | Antibiot Annu | pmid:13355244 |
CALESNICK B | Effectiveness of oral erythromycin propionate in commonly occurring infections. | 1959-1960 | Antibiot Annu | pmid:13806941 |
DAVIS DS et al. | The treatment of one hundred and seventy-one patients with erythromycin, including one hundred and thirty-two with bacterial pneumonia. | 1955-1956 | Antibiot Annu | pmid:13355245 |
LOUGHLIN EH et al. | Antibiotic therapy of acute gonococcal infections; a study of the comparative efficacy of triacetyloleandomycin, erythromycin, and penicillin V in the treatment of acute gonococcal urethritis. | 1958-1959 | Antibiot Annu | pmid:13637747 |
STEPHENS VC and CONINE JW | Esters of erythromycin. III. Esters of low molecular weight aliphatic acids. | 1958-1959 | Antibiot Annu | pmid:13637765 |
LEE CC et al. | Pharmacology and toxicology of erythromycin propionate. | 1958-1959 | Antibiot Annu | pmid:13637766 |
GRIFFITH RS | Laboratory and clinical studies with erythromycin propionate. | 1958-1959 | Antibiot Annu | pmid:13637767 |
PERRY DM et al. | Clinical and laboratory studies of erythromycin propionate. | 1958-1959 | Antibiot Annu | pmid:13637768 |
MARMELL M et al. | Clinical trial of erythromycin propionate for acute anterior gonococcal urethritis. | 1959-1960 | Antibiot Annu | pmid:14421354 |
REICHELDERFER TE et al. | Clinical studies of propionyl erythromycin lauryl sulfate in children. | 1959-1960 | Antibiot Annu | pmid:14437052 |