erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nagai K et al. | Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. | 2001 | Antimicrob. Agents Chemother. | pmid:11600391 |
| Hsueh PR et al. | High incidence of erythromycin resistance among clinical isolates of Streptococcus agalactiae in Taiwan. | 2001 | Antimicrob. Agents Chemother. | pmid:11600380 |
| Cave VG | The management of the several stages of syphilis. | 1975 | J Natl Med Assoc | pmid:1159858 |
| Singer JI and DeVoe WM | Severe Mycoplasma pneumoniae infection in otherwise healthy siblings. | 1979 | J. Pediatr. | pmid:115983 |
| Buitendijk SE | Antibiotics in preterm labour. | 2001 | Lancet | pmid:11597708 |
| Culasso C et al. | [Streptococcus pneumoniae: evolution of antibiotic resistance in a pediatric hospital in Córdoba, Argentina]. | 2001 Jul-Sep | Rev. Argent. Microbiol. | pmid:11594005 |
| Buitendijk SE | [Erythromycin for premature rupture of membranes is beneficial for infant]. | 2001 | Ned Tijdschr Geneeskd | pmid:11593784 |
| Okazaki N et al. | Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. | 2001 | Microbiol. Immunol. | pmid:11592636 |
| Kashimura M et al. | Synthesis and antibacterial activity of the tricyclic ketolides TE-802 and its analogs. | 2001 | J. Antibiot. | pmid:11592503 |
| Nourse JG and Roberts JD | Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of some macrolide antibiotics and derivatives. Substituent and conformational effects. | 1975 | J. Am. Chem. Soc. | pmid:1159223 |
| Egan RS et al. | Conformational flexibility of erythronolide B, the 14-membered aglycon ring of the erythromycins. | 1975 | J. Am. Chem. Soc. | pmid:1159222 |
| Stary A | European guideline for the management of chlamydial infection. | 2001 | Int J STD AIDS | pmid:11589794 |
| Altindis M et al. | Turkish primary school students as carriers of group A beta-hemolytic streptococci and susceptibility of strains to penicillin and erythromycin. | 2001 | J Chemother | pmid:11589490 |
| Bennett S et al. | Treatment practices for chlamydial infection in New Zealand. | 2001 | N. Z. Med. J. | pmid:11589434 |
| Boivin MA and Levy H | Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill. | 2001 | Crit. Care Med. | pmid:11588451 |
| Tenson T and Mankin AS | Short peptides conferring resistance to macrolide antibiotics. | 2001 | Peptides | pmid:11587794 |
| Azuma A et al. | Prolonged survival of a bare lymphocyte syndrome type I patient with diffuse panbronchiolitis treated with erythromycin. | 2001 | Sarcoidosis Vasc Diffuse Lung Dis | pmid:11587107 |
| Ramaswamy K and Jacobson K | Infectious diarrhea in children. | 2001 | Gastroenterol. Clin. North Am. | pmid:11586548 |
| Blum M et al. | [Transfer of antibiotics across the placenta in early pregnancy]. | 1975 | Harefuah | pmid:1158197 |
| Aracil B et al. | High prevalence of erythromycin-resistant and clindamycin-susceptible (M phenotype) viridans group streptococci from pharyngeal samples: a reservoir of mef genes in commensal bacteria. | 2001 | J. Antimicrob. Chemother. | pmid:11581247 |
| Spurlock G et al. | Erythromycin binding studies on two different classes of antibiotic resistant mutant in Paramecium. | 1975 | FEBS Lett. | pmid:1157936 |
| Korycka-Machala M et al. | Polycations increase the permeability of Mycobacterium vaccae cell envelopes to hydrophobic compounds. | 2001 | Microbiology (Reading, Engl.) | pmid:11577156 |
| Farrow KA et al. | Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile. | 2001 | Microbiology (Reading, Engl.) | pmid:11577151 |
| Li XC et al. | A new naphthopyrone derivative from Cassia quinquangulata and structural revision of quinquangulin and its glycosides. | 2001 | J. Nat. Prod. | pmid:11575947 |
| MÃ¥rdh PA | Human respiratory tract infections with mycoplasmas and their in vitro susceptibility to tetracyclines and some other antibiotics. | 1975 | Chemotherapy | pmid:1157581 |
| Rubinstein E | Comparative safety of the different macrolides. | 2001 | Int. J. Antimicrob. Agents | pmid:11574199 |
| Pechère JC | Macrolide resistance mechanisms in Gram-positive cocci. | 2001 | Int. J. Antimicrob. Agents | pmid:11574191 |
| Zatman TF et al. | Gastric residual volume in children: a study comparing efficiency of erythromycin and metoclopramide as prokinetic agents. | 2001 | Br J Anaesth | pmid:11573597 |
| Lawrence LE | ABT-773 (Abbott Laboratories). | 2001 | Curr Opin Investig Drugs | pmid:11572654 |
| Afset JE and Maeland JA | [Erythromycin and ciprofloxacin resistant Campylobacter jejuni]. | 2001 | Tidsskr. Nor. Laegeforen. | pmid:11571989 |
| Douthwaite S and Champney WS | Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site. | 2001 | J. Antimicrob. Chemother. | pmid:11566971 |
| Peeters TL | GM-611 (Chugai Pharmaceutical). | 2001 | Curr Opin Investig Drugs | pmid:11566017 |
| Merits I | The metabolism of labelled hexadecyl sulphate salts in the rat, dog and human. | 1975 | Biochem. J. | pmid:1156404 |
| Mahon BE et al. | Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis. | 2001 | J. Pediatr. | pmid:11562617 |
| Wu YJ and Su WG | Recent developments on ketolides and macrolides. | 2001 | Curr. Med. Chem. | pmid:11562291 |
| Barry AL et al. | Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11561807 |
| Nishimoto A et al. | Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex. | 2001 | Chem. Pharm. Bull. | pmid:11558597 |
| Yu KS et al. | Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin. | 2001 | Clin. Pharmacol. Ther. | pmid:11557910 |
| Barry AL et al. | In vitro activity of the ketolide ABT-773. | 2001 | Antimicrob. Agents Chemother. | pmid:11557491 |
| Edelstein PH et al. | In vitro activity of ABT-773 against Legionella pneumophila, its pharmacokinetics in guinea pigs, and its use to treat guinea pigs with L. pneumophila pneumonia. | 2001 | Antimicrob. Agents Chemother. | pmid:11557455 |
| Suzuki T et al. | Erythromycin and common cold in COPD. | 2001 | Chest | pmid:11555501 |
| Gaisser S et al. | New erythromycin derivatives from Saccharopolyspora erythraea using sugar O-methyltransferases from the spinosyn biosynthetic gene cluster. | 2001 | Mol. Microbiol. | pmid:11555300 |
| Draisci R et al. | Confirmatory method for macrolide residues in bovine tissues by micro-liquid chromatography-tandem mass spectrometry. | 2001 | J Chromatogr A | pmid:11554423 |
| Kitamura M et al. | Stereochemistry of aldols: configuration and conformation of aldols derived from cycloalkanones and aldehydes. | 2001 | J. Am. Chem. Soc. | pmid:11552800 |
| Bojarska-Dahlig H et al. | [Salts of cyclic erythromycin A carbonate with cinnamic acid derivatives]. | 1975 | Acta Pol Pharm | pmid:1155186 |
| Axelsson A et al. | Treatment of acute maxillary sinusitis. IV. Ampicillin, cephradine and erythromycinestolate with and without irrigation. | 1975 May-Jun | Acta Otolaryngol. | pmid:1155056 |
| Yamanaka Y et al. | Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11549274 |
| Staunton J and Weissman KJ | Polyketide biosynthesis: a millennium review. | 2001 | Nat Prod Rep | pmid:11548049 |
| GarcÃa Aroca J et al. | [Anorexia nervosa or somatic disease]. | 2001 | Cir Pediatr | pmid:11547640 |
| Silk PJ et al. | Chlorometabolite production by the ecologically important white rot fungus Bjerkandera adusta. | 2001 | Chemosphere | pmid:11545526 |
| Kobayashi N et al. | Novel macrolide-specific ABC-type efflux transporter in Escherichia coli. | 2001 | J. Bacteriol. | pmid:11544226 |
| Tixador R et al. | Preliminary results of Cytos 2 experiment. | 1985 | Acta Astronaut | pmid:11542841 |
| Uzun C et al. | Reversible ototoxic effect of azithromycin and clarithromycin on transiently evoked otoacoustic emissions in guinea pigs. | 2001 | J Laryngol Otol | pmid:11535141 |
| Guerrero Igea FJ et al. | [Acute pancreatitis caused by erythromycin]. | 2001 | An Med Interna | pmid:11534437 |
| Moore JE et al. | Antibiotic resistance in Campylobacter spp. isolated from human faeces (1980-2000) and foods (1997-2000) in Northern Ireland: an update. | 2001 | J. Antimicrob. Chemother. | pmid:11533022 |
| Hunfeld KP et al. | In vitro susceptibility of the Borrelia burgdorferi sensu lato complex to ABT-773, a novel ketolide. | 2001 | J. Antimicrob. Chemother. | pmid:11533017 |
| Weiss K et al. | In vitro activity of a novel ketolide ABT-773 against invasive strains of Streptococcus pneumoniae. | 2001 | J. Antimicrob. Chemother. | pmid:11533007 |
| Schlegel L et al. | In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. | 2001 | Clin. Microbiol. Infect. | pmid:11531981 |
| Cunliffe WJ et al. | A clinical and therapeutic study of 29 patients with infantile acne. | 2001 | Br. J. Dermatol. | pmid:11531837 |
| Ou MC et al. | Antibiotic treatment for threatened abortion during the early first trimester in women with previous spontaneous abortion. | 2001 | Acta Obstet Gynecol Scand | pmid:11531620 |
| Celik H et al. | Effects of erythromycin on stretch-induced contractile activity of isolated myometrium from pregnant women. | 2001 | Acta Obstet Gynecol Scand | pmid:11531610 |
| Miyashita N et al. | [A case of Coxiella burnetii pneumonia in an adult]. | 2001 | Nihon Kokyuki Gakkai Zasshi | pmid:11530397 |
| Oei J and Lui K | A placebo-controlled trial of low-dose erythromycin to promote feed tolerance in preterm infants. | 2001 | Acta Paediatr. | pmid:11529540 |
| Schlienger RG et al. | Risk of cataract in patients treated with statins. | 2001 | Arch. Intern. Med. | pmid:11525705 |
| MartÃnez MA et al. | Occurrence and antimicrobial susceptibility of Ureaplasma parvum (Ureaplasma urealyticum biovar 1) and Ureaplasma urealyticum (Ureaplasma urealyticum biovar 2) from patients with adverse pregnancy outcomes and normal pregnant women. | 2001 | Scand. J. Infect. Dis. | pmid:11525356 |
| Katagiri K et al. | Staphylococcal footpad infection in mice. | 1975 | Jpn. J. Microbiol. | pmid:1152301 |
| Spector R | The transport of gentamicin in the choroid plexus and cerebrospinal fluid. | 1975 | J. Pharmacol. Exp. Ther. | pmid:1151757 |
| Willan AR | Broad-spectrum antibiotics in ORACLE. | 2001 | Lancet | pmid:11515508 |
| Bernabéu JA et al. | Procedure to evaluate the stability during processing and storage of a medicated premix and medicated farm feed: erythromycin thiocyanate. | 2001 | J. Agric. Food Chem. | pmid:11513652 |
| Shengxi C et al. | 3-Keto-9-O-substituted oxime derivatives of 6-O-methyl erythromycin A synthesis and in vitro activity. | 2001 | J. Antibiot. | pmid:11513040 |
| Talley NJ et al. | Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial. | 2001 | Gut | pmid:11511562 |
| Gabashvili IS et al. | The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. | 2001 | Mol. Cell | pmid:11511371 |
| Pelletier LL et al. | Chemotherapy of experimental streptococcal endocarditis. IV. Further observations on prophylaxis. | 1975 | J. Clin. Invest. | pmid:1150874 |
| Flickinger MC and Perlman D | Microbial degradation of erythromycins A and B. | 1975 | J. Antibiot. | pmid:1150530 |
| Erythromycin-induced pyloric stenosis in infants. | 2001 | Prescrire Int | pmid:11503852 | |
| Choosing a macrolide: drug interactions must be taken into account. | 1999 | Prescrire Int | pmid:11503822 | |
| de Mey C et al. | Erythromycin increases plasma concentrations of alpha-dihydroergocryptine in humans. | 2001 | Clin. Pharmacol. Ther. | pmid:11503008 |
| Byarugaba W et al. | Toxicity of antibiotics on cultured human skin fibroblasts. | 1975 | Humangenetik | pmid:1150286 |
| Mavroidi A et al. | Multidrug-resistant strains of Neisseria gonorrhoeae in Greece. | 2001 | Antimicrob. Agents Chemother. | pmid:11502546 |
| Kenny GE and Cartwright FD | Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines, and quinolones. | 2001 | Antimicrob. Agents Chemother. | pmid:11502536 |
| Mitten MJ et al. | Efficacies of ABT-773, a new ketolide, against experimental bacterial infections. | 2001 | Antimicrob. Agents Chemother. | pmid:11502533 |
| Morosini MI et al. | In vitro activity of telithromycin against Spanish Streptococcus pneumoniae isolates with characterized macrolide resistance mechanisms. | 2001 | Antimicrob. Agents Chemother. | pmid:11502509 |
| Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. | 2001 | Eur. J. Cell Biol. | pmid:11499789 |
| Eagle DA et al. | Gastroparesis following bone marrow transplantation. | 2001 | Bone Marrow Transplant. | pmid:11498745 |
| Farpour B and McClellan KA | Diagnosis and management of chronic blepharokeratoconjunctivitis in children. | 2001 Jul-Aug | J Pediatr Ophthalmol Strabismus | pmid:11495307 |
| Welling PG et al. | Prediction of drug dosage in patients with renal failure using data derived from normal subjects. | 1975 | Clin. Pharmacol. Ther. | pmid:1149361 |
| Emoto C et al. | Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. | 2001 | Xenobiotica | pmid:11491388 |
| Grier M et al. | Do antibiotics improve neonatal outcomes in preterm premature rupture of membranes (PPROM)? | 2001 | J Fam Pract | pmid:11485716 |
| Lombó F et al. | Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering. | 2001 Jul-Aug | Biotechnol. Prog. | pmid:11485419 |
| Rudolph KM et al. | Mechanisms of erythromycin and trimethoprim resistance in the Alaskan Streptococcus pneumoniae serotype 6B clone. | 2001 | J. Antimicrob. Chemother. | pmid:11481311 |
| Schultz MJ et al. | Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor-alpha production in human whole blood. | 2001 | J. Antimicrob. Chemother. | pmid:11481300 |
| Van Looveren M et al. | Antimicrobial susceptibilities of Campylobacter strains isolated from food animals in Belgium. | 2001 | J. Antimicrob. Chemother. | pmid:11481294 |
| Polyzou A et al. | Predominance of a methicillin-resistant Staphylococcus aureus clone susceptible to erythromycin and several other non-beta-lactam antibiotics in a Greek hospital. | 2001 | J. Antimicrob. Chemother. | pmid:11481293 |
| Pérez-Trallero E et al. | High proportion of pharyngeal carriers of commensal streptococci resistant to erythromycin in Spanish adults. | 2001 | J. Antimicrob. Chemother. | pmid:11481292 |
| Ulvatne H et al. | Short antibacterial peptides and erythromycin act synergically against Escherichia coli. | 2001 | J. Antimicrob. Chemother. | pmid:11481289 |
| Nolting S | [The current situation of syphilis. Diagnosis by exact serological studies or direct demonstration of treponemas]. | 1979 | MMW Munch Med Wochenschr | pmid:114807 |
| Cooke RW | Bacteroides fragilis septicaemia and meningitis in early infancy. | 1975 | Arch. Dis. Child. | pmid:1147659 |
| Whittle G et al. | Characterization of the 13-kilobase ermF region of the Bacteroides conjugative transposon CTnDOT. | 2001 | Appl. Environ. Microbiol. | pmid:11472924 |
| Le Sage N et al. | Efficacy of eye patching for traumatic corneal abrasions: a controlled clinical trial. | 2001 | Ann Emerg Med | pmid:11468606 |
| Davydova N et al. | Crystals of a mutant form of ribosomal protein L22 rendering bacterial ribosomes resistant to erythromycin. | 2001 | Acta Crystallogr. D Biol. Crystallogr. | pmid:11468402 |