erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Palmieri C et al. | Interspecies mobilization of an ermT-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. | 2013 | J. Antimicrob. Chemother. | pmid:22949621 |
González-Hein G et al. | [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. | 2013 | Rev Chilena Infectol | pmid:23677151 |
Adhikari MD et al. | Membrane-directed high bactericidal activity of (gold nanoparticle)-polythiophene composite for niche applications against pathogenic bacteria. | 2013 | Adv Healthc Mater | pmid:23184755 |
Utsunomiya S et al. | Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. | 2013 | Regul. Pept. | pmid:23142315 |
Li YJ et al. | EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. | 2013 | Pulm Pharmacol Ther | pmid:23291319 |
Henson AM et al. | Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. | 2013 | J. Clin. Microbiol. | pmid:24048538 |
Wieczorek K et al. | Prevalence and antimicrobial resistance of Campylobacter spp. isolated from poultry carcasses in Poland. | 2013 | J. Food Prot. | pmid:23905805 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). | 2013 | J. Fish Dis. | pmid:24118016 |
Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
Kelley C et al. | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. | 2013 | Eur J Med Chem | pmid:23314053 |
Atamanyuk D et al. | Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. | 2013 | J. Med. Chem. | pmid:23445125 |
Gomes DL et al. | SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. | 2013 | J. Med. Microbiol. | pmid:23449875 |
Yang M et al. | Macrolides for diffuse panbronchiolitis. | 2013 | Cochrane Database Syst Rev | pmid:23450579 |
Schafer F et al. | Antimicrobial susceptibility and genetic characteristics of Propionibacterium acnes isolated from patients with acne. | 2013 | Int. J. Dermatol. | pmid:23432195 |
Chen Y et al. | Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. | 2013 | Bioresour. Technol. | pmid:23500575 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Basak R and Bandyopadhyay R | Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. | 2013 | Langmuir | pmid:23472840 |
Capanna F et al. | Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. | 2013 | Swiss Med Wkly | pmid:23572445 |
Yadav DK et al. | Failure of secondary prophylaxis with erythromycin in rheumatic heart disease. | 2013 | Indian Pediatr | pmid:24382905 |
Chen Y et al. | Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. | 2013 | Bioprocess Biosyst Eng | pmid:23361182 |
Melnik BC and Schmitz G | Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? | 2013 | Exp. Dermatol. | pmid:23800068 |
Ragazzi E et al. | Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. | 2013 | J Chemother | pmid:23684362 |
Rasamiravaka T et al. | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. | 2013 | J Infect Dev Ctries | pmid:23592641 |
Nakajima T et al. | Absence of intervening sequences and point mutations in the V domain within 23S rRNA in Campylobacter lari isolates. | 2013 | Folia Microbiol. (Praha) | pmid:23595231 |
Ma X et al. | Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children. | 2013 | Chin. Med. J. | pmid:23595388 |
Hinarejos P et al. | The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. | 2013 | J Bone Joint Surg Am | pmid:23636182 |
Gao X et al. | Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. | 2013 | J. Am. Chem. Soc. | pmid:23464668 |
Roberts DW | What is the role of antibiotic-containing cement in total knee arthroplasty? | 2013 | J Bone Joint Surg Am | pmid:23636201 |
Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
Gonçalves A et al. | Antimicrobial resistance in faecal enterococci and Escherichia coli isolates recovered from Iberian wolf. | 2013 | Lett. Appl. Microbiol. | pmid:23336611 |
Rożynek E et al. | Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. | 2013 | Foodborne Pathog. Dis. | pmid:23638847 |
Grabowicz M et al. | Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. | 2013 | J. Bacteriol. | pmid:23316047 |
Dubey D et al. | A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. | 2013 | Asian Pac J Trop Biomed | pmid:23593595 |
Marcellin E et al. | Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. | 2013 | BMC Genomics | pmid:23324121 |
Baltar F et al. | Bacterial versus archaeal origin of extracellular enzymatic activity in the Northeast Atlantic deep waters. | 2013 | Microb. Ecol. | pmid:23015014 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
Wang J et al. | Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. | 2014 | Hum. Immunol. | pmid:24120738 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Nikolay R et al. | Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. | 2014 | Nucleic Acids Res. | pmid:24792169 |
Sanamrad A et al. | Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25056965 |
Shim J et al. | Clinical inquiry: what is the best treatment for impetigo ? | 2014 | J Fam Pract | pmid:25061625 |
Krishnappa LG et al. | Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. | 2014 | Acta Microbiol Immunol Hung | pmid:24939685 |
Florindo C et al. | Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. | 2014 | Euro Surveill. | pmid:24957747 |
Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
Miyazaki M et al. | [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. | 2014 | Yakugaku Zasshi | pmid:24492229 |
Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
ŽemliÄková H et al. | [Resistance monitoring working group: resistance to erythromycin, ciprofloxacin, and tetracycline in human isolates of Campylobacter spp. in the Czech Republic tested by the EUCAST standard method]. | 2014 | Epidemiol Mikrobiol Imunol | pmid:25412481 |
Arêas GP et al. | Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. | 2014 | Mem. Inst. Oswaldo Cruz | pmid:25410998 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Wu H et al. | Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. | 2014 | Microb. Cell Fact. | pmid:25391994 |
Caierão J et al. | Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. | 2014 | PLoS ONE | pmid:25356595 |
Labbeiki G et al. | Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. | 2014 | Daru | pmid:25223458 |
Bharucha AE et al. | A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. | 2014 | Eur J Radiol | pmid:25217123 |
Johnson SR et al. | In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. | 2014 | Antimicrob. Agents Chemother. | pmid:25199775 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Shera IA et al. | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. | 2014 | J Med Case Rep | pmid:25194644 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Wyatt TA et al. | cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. | 2014 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25150062 |
Abarzúa F et al. | [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at ClÃnica Alemana Temuco, Southern Chile]. | 2014 | Rev Chilena Infectol | pmid:25146205 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
Mayanskiy N et al. | Serotypes and antibiotic resistance of non-invasive Streptococcus pneumoniae circulating in pediatric hospitals in Moscow, Russia. | 2014 | Int. J. Infect. Dis. | pmid:24462930 |
Moore KT et al. | An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. | 2014 | J Clin Pharmacol | pmid:24964176 |
Montilla A et al. | Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. | 2014 | Antimicrob. Agents Chemother. | pmid:24957835 |
Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Arana DM et al. | First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene. | 2014 | Rev Esp Quimioter | pmid:24940891 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Luan R et al. | [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. | 2014 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:24912643 |
Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Johansson M et al. | Sequence-dependent elongation dynamics on macrolide-bound ribosomes. | 2014 | Cell Rep | pmid:24836000 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
Allen LN | Mild meningococcaemia, pyrexia protocols and a problematic public health response. | 2014 | BMJ Case Rep | pmid:24811106 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
Heriot WJ et al. | Ocular involvement in a patient with Legionella longbeachae 1 infection. | 2014 | Clin. Experiment. Ophthalmol. | pmid:24650007 |
Calvert H et al. | Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. | 2014 | Anticancer Drugs | pmid:24637575 |
Janoir C et al. | Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. | 2014 | PLoS ONE | pmid:24603763 |
Melnik BC | The P450 system and mTORC1 signalling in acne. | 2014 | Exp. Dermatol. | pmid:24588627 |
Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
Montes M et al. | What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. | 2014 | J. Antimicrob. Chemother. | pmid:24562616 |
Benito D et al. | Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. | 2014 | Foodborne Pathog. Dis. | pmid:24479575 |
Boomkamp SD et al. | Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. | 2014 | Br. J. Pharmacol. | pmid:24467222 |
Jun BY et al. | Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. | 2014 | Surg Endosc | pmid:24380989 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |