erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen D et al. | Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. | 2014 | PLoS ONE | pmid:25250723 |
Ishibashi K et al. | Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial. | 2014 | Surg. Today | pmid:23989910 |
Wang J et al. | Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. | 2014 | Hum. Immunol. | pmid:24120738 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Blattner C et al. | A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. | 2014 | J. Cutan. Pathol. | pmid:24588271 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
Yu ZC et al. | Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. | 2014 | Microb. Cell Fact. | pmid:24450434 |
Barnes P and Chauhan M | Chancroid - desperate patient makes own diagnosis. | 2014 | Int J STD AIDS | pmid:24535694 |
Wang S et al. | Comparison of microbial communities in sequencing batch reactors (SBRs) exposed to trace erythromycin and erythromycin-Hâ‚‚O. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24072160 |
Barbosa TM et al. | A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. | 2014 | PLoS ONE | pmid:25548909 |
Liao D et al. | Quantitative differences between primary and secondary peristaltic contractions of the esophagus. | 2014 | Dig. Dis. Sci. | pmid:24682721 |
Hudson BH and Zaher HS | Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. | 2014 | Mol. Cell | pmid:25514181 |
Pinto TC et al. | Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. | 2014 | Braz. J. Microbiol. | pmid:25477908 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Luminos M et al. | Nasopharyngeal carriage of Streptococcus pneumoniae in Romanian children before the introduction of the pneumococcal conjugated vaccination into the national immunization programme: a national, multi-centre, cross-sectional observational study. | 2014 | Int. J. Infect. Dis. | pmid:25461243 |
Silva CM et al. | Population dynamics and antimicrobial susceptibility of Aeromonas spp. along a salinity gradient in an urban estuary in Northeastern Brazil. | 2014 | Mar. Pollut. Bull. | pmid:25455376 |
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Arêas GP et al. | Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. | 2014 | Mem. Inst. Oswaldo Cruz | pmid:25410998 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Farabella I et al. | Allosteric signalling in the outer membrane translocation domain of PapC usher. | 2014 | Elife | pmid:25271373 |
Jaiswal N et al. | Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. | 2014 | PLoS ONE | pmid:25268974 |
Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
Bauer CA and Grimme S | First principles calculation of electron ionization mass spectra for selected organic drug molecules. | 2014 | Org. Biomol. Chem. | pmid:25260171 |
Sugawara E and Nikaido H | Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli. | 2014 | Antimicrob. Agents Chemother. | pmid:25246403 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Ziupa D et al. | Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. | 2014 | PLoS ONE | pmid:25244401 |
Westerhof J et al. | Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. | 2014 | BMC Gastroenterol | pmid:25234278 |
Badri T et al. | [Erythrasma: study of 16 cases]. | 2014 | Tunis Med | pmid:25224418 |
Dörries K et al. | Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. | 2014 | Antimicrob. Agents Chemother. | pmid:25224006 |
Labbeiki G et al. | Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. | 2014 | Daru | pmid:25223458 |
Bharucha AE et al. | A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. | 2014 | Eur J Radiol | pmid:25217123 |
Johnson SR et al. | In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. | 2014 | Antimicrob. Agents Chemother. | pmid:25199775 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Shera IA et al. | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. | 2014 | J Med Case Rep | pmid:25194644 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Bos JC et al. | Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. | 2014 | BMC Res Notes | pmid:24568650 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Flamm RK et al. | Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. | 2014 | Antimicrob. Agents Chemother. | pmid:24514082 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Arakawa K | Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25036669 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Mott M et al. | Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil. | 2014 | Int. J. Infect. Dis. | pmid:24389158 |
Nuyujukian DS et al. | Medication use and multiple myeloma risk in Los Angeles County. | 2014 | Cancer Causes Control | pmid:24981100 |
Iatrou EI et al. | Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24981036 |
Mayanskiy N et al. | Serotypes and antibiotic resistance of non-invasive Streptococcus pneumoniae circulating in pediatric hospitals in Moscow, Russia. | 2014 | Int. J. Infect. Dis. | pmid:24462930 |
Ramos V et al. | [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. | 2014 | Biomedica | pmid:24968052 |
Moore KT et al. | An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. | 2014 | J Clin Pharmacol | pmid:24964176 |
Montilla A et al. | Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. | 2014 | Antimicrob. Agents Chemother. | pmid:24957835 |
Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Arana DM et al. | First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene. | 2014 | Rev Esp Quimioter | pmid:24940891 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Luan R et al. | [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. | 2014 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:24912643 |
Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
Kawaguchiya M et al. | Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. | 2014 | Microb. Drug Resist. | pmid:24766085 |
Gaudreau C et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolates obtained in Montreal, Quebec, Canada, from 2002 to 2013. | 2014 | J. Clin. Microbiol. | pmid:24759726 |
Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Moreno LZ et al. | Characterization of antibiotic resistance in Listeria spp. isolated from slaughterhouse environments, pork and human infections. | 2014 | J Infect Dev Ctries | pmid:24727506 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Yosida M et al. | Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. | 2014 | Diabetes | pmid:24824430 |
Hellmann-Regen J et al. | Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? | 2014 | Exp. Dermatol. | pmid:24690039 |
Siira L et al. | Antimicrobial resistance in relation to sero- and genotypes among invasive Streptococcus pneumoniae in Finland, 2007-2011. | 2014 | Microb. Drug Resist. | pmid:24266666 |
Xu J et al. | Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. | 2014 | J. Food Sci. | pmid:24689704 |
Wang D et al. | Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. | 2014 | Microb. Drug Resist. | pmid:24684286 |
Arenz S et al. | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. | 2014 | Nat Commun | pmid:24662426 |
Fernández Fuentes MA et al. | Synergistic activity of biocides and antibiotics on resistant bacteria from organically produced foods. | 2014 | Microb. Drug Resist. | pmid:24660956 |
Heriot WJ et al. | Ocular involvement in a patient with Legionella longbeachae 1 infection. | 2014 | Clin. Experiment. Ophthalmol. | pmid:24650007 |
Calvert H et al. | Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. | 2014 | Anticancer Drugs | pmid:24637575 |
Janoir C et al. | Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. | 2014 | PLoS ONE | pmid:24603763 |
Melnik BC | The P450 system and mTORC1 signalling in acne. | 2014 | Exp. Dermatol. | pmid:24588627 |
Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
Zheng PX et al. | Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. | 2014 | Clin. Microbiol. Infect. | pmid:24118239 |
Singh P et al. | Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. | 2014 | Fundam Clin Pharmacol | pmid:24117516 |
Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Wang P et al. | Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. | 2015 | Int. J. Infect. Dis. | pmid:26141418 |
Høye S | An extraordinary tale of an ordinary case. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130550 |
Loose LM et al. | Adolescent with respiratory impairments and short-lived fever. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130549 |
Koutsogiannidis CP et al. | Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. | 2015 | J Card Surg | pmid:25858150 |
KovaÄ J et al. | Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. | 2015 | PLoS ONE | pmid:25830640 |
van Eijk E et al. | Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. | 2015 | BMC Genomics | pmid:25636331 |
Gao P et al. | Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25631280 |
Lin X et al. | Macrolides for diffuse panbronchiolitis. | 2015 | Cochrane Database Syst Rev | pmid:25618845 |
Blix HS et al. | Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? | 2015 | Epidemiol. Infect. | pmid:25388750 |
MarÃn M et al. | Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. | 2015 | Antimicrob. Agents Chemother. | pmid:25385106 |
Lo HH et al. | Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. | 2015 | J Microbiol Immunol Infect | pmid:24856419 |
Cheng C et al. | Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. | 2015 | Pathol. Res. Pract. | pmid:26601615 |
Michael-Kordatou I et al. | Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. | 2015 | Water Res. | pmid:26360228 |