erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ou MC et al. | Antibiotic treatment for threatened abortion during the early first trimester in women with previous spontaneous abortion. | 2001 | Acta Obstet Gynecol Scand | pmid:11531620 |
Cunliffe WJ et al. | A clinical and therapeutic study of 29 patients with infantile acne. | 2001 | Br. J. Dermatol. | pmid:11531837 |
Schlegel L et al. | In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. | 2001 | Clin. Microbiol. Infect. | pmid:11531981 |
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Yamanaka Y et al. | Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11549274 |
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Edelstein PH et al. | In vitro activity of ABT-773 against Legionella pneumophila, its pharmacokinetics in guinea pigs, and its use to treat guinea pigs with L. pneumophila pneumonia. | 2001 | Antimicrob. Agents Chemother. | pmid:11557455 |
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Yu KS et al. | Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin. | 2001 | Clin. Pharmacol. Ther. | pmid:11557910 |
Nishimoto A et al. | Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex. | 2001 | Chem. Pharm. Bull. | pmid:11558597 |
Barry AL et al. | Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11561807 |
Wu YJ and Su WG | Recent developments on ketolides and macrolides. | 2001 | Curr. Med. Chem. | pmid:11562291 |
Mahon BE et al. | Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis. | 2001 | J. Pediatr. | pmid:11562617 |
Merits I | The metabolism of labelled hexadecyl sulphate salts in the rat, dog and human. | 1975 | Biochem. J. | pmid:1156404 |
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Douthwaite S and Champney WS | Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site. | 2001 | J. Antimicrob. Chemother. | pmid:11566971 |
Afset JE and Maeland JA | [Erythromycin and ciprofloxacin resistant Campylobacter jejuni]. | 2001 | Tidsskr. Nor. Laegeforen. | pmid:11571989 |
Lawrence LE | ABT-773 (Abbott Laboratories). | 2001 | Curr Opin Investig Drugs | pmid:11572654 |
Zatman TF et al. | Gastric residual volume in children: a study comparing efficiency of erythromycin and metoclopramide as prokinetic agents. | 2001 | Br J Anaesth | pmid:11573597 |
Pechère JC | Macrolide resistance mechanisms in Gram-positive cocci. | 2001 | Int. J. Antimicrob. Agents | pmid:11574191 |
Rubinstein E | Comparative safety of the different macrolides. | 2001 | Int. J. Antimicrob. Agents | pmid:11574199 |
MÃ¥rdh PA | Human respiratory tract infections with mycoplasmas and their in vitro susceptibility to tetracyclines and some other antibiotics. | 1975 | Chemotherapy | pmid:1157581 |
Li XC et al. | A new naphthopyrone derivative from Cassia quinquangulata and structural revision of quinquangulin and its glycosides. | 2001 | J. Nat. Prod. | pmid:11575947 |
Farrow KA et al. | Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile. | 2001 | Microbiology (Reading, Engl.) | pmid:11577151 |
Korycka-Machala M et al. | Polycations increase the permeability of Mycobacterium vaccae cell envelopes to hydrophobic compounds. | 2001 | Microbiology (Reading, Engl.) | pmid:11577156 |
Spurlock G et al. | Erythromycin binding studies on two different classes of antibiotic resistant mutant in Paramecium. | 1975 | FEBS Lett. | pmid:1157936 |
Aracil B et al. | High prevalence of erythromycin-resistant and clindamycin-susceptible (M phenotype) viridans group streptococci from pharyngeal samples: a reservoir of mef genes in commensal bacteria. | 2001 | J. Antimicrob. Chemother. | pmid:11581247 |
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Azuma A et al. | Prolonged survival of a bare lymphocyte syndrome type I patient with diffuse panbronchiolitis treated with erythromycin. | 2001 | Sarcoidosis Vasc Diffuse Lung Dis | pmid:11587107 |
Tenson T and Mankin AS | Short peptides conferring resistance to macrolide antibiotics. | 2001 | Peptides | pmid:11587794 |
Boivin MA and Levy H | Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill. | 2001 | Crit. Care Med. | pmid:11588451 |
Bennett S et al. | Treatment practices for chlamydial infection in New Zealand. | 2001 | N. Z. Med. J. | pmid:11589434 |
Altindis M et al. | Turkish primary school students as carriers of group A beta-hemolytic streptococci and susceptibility of strains to penicillin and erythromycin. | 2001 | J Chemother | pmid:11589490 |
Stary A | European guideline for the management of chlamydial infection. | 2001 | Int J STD AIDS | pmid:11589794 |
Egan RS et al. | Conformational flexibility of erythronolide B, the 14-membered aglycon ring of the erythromycins. | 1975 | J. Am. Chem. Soc. | pmid:1159222 |