erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Walkey AJ and Wiener RS | Macrolide antibiotics and survival in patients with acute lung injury. | 2012 | Chest | pmid:22116799 |
| Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
| Zou MX et al. | Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. | 2012 | Chin. Med. J. | pmid:22882850 |
| Dekio I | Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? | 2012 | J. Dermatol. | pmid:22224953 |
| Kim J et al. | Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. | 2012 | J. Microbiol. | pmid:22752920 |
| Arakawa K et al. | The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. | 2012 | Chembiochem | pmid:22761035 |
| Licona-Cassani C et al. | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. | 2012 | Antonie Van Leeuwenhoek | pmid:22847261 |
| Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. | 2012 | Prescrire Int | pmid:22852287 | |
| Kim EY et al. | The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. | 2012 | Acta Radiol | pmid:22855416 |
| Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
| Perry DM et al. | Identification and characterization of protein phosphatase 2C activation by ceramide. | 2012 | J. Lipid Res. | pmid:22615346 |
| Geddes BA and Oresnik IJ | Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. | 2012 | Microbiology (Reading, Engl.) | pmid:22609752 |
| Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
| Bidet P et al. | Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22610663 |
| Liu X et al. | [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. | 2012 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:23156807 |
| Chen X et al. | Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122862 |
| Tolosa L et al. | Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 | Toxicol. Sci. | pmid:22331495 |
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| Jordan PA and Miller SJ | An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22319027 |
| Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
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| Zhang W et al. | Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. | 2011 | Curr. Microbiol. | pmid:20924584 |
| Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
| Nakashima R et al. | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. | 2011 | Nature | pmid:22121023 |
| Song W et al. | Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. | 2011 | Int J Nanomedicine | pmid:22228990 |
| Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
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| Zhang Q et al. | Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. | 2011 | Lett. Appl. Microbiol. | pmid:21175699 |
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| Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
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| Andini N and Nash KA | Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. | 2011 | FEMS Microbiol. Lett. | pmid:21718348 |
| Li AP and Doshi U | Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. | 2011 | Drug Metab Lett | pmid:21722087 |
| Imperi M et al. | Invasive neonatal GBS infections from an area-based surveillance study in Italy. | 2011 | Clin. Microbiol. Infect. | pmid:21722258 |
| Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
| Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
| Miyashita N et al. | Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. | 2011 | J. Infect. Chemother. | pmid:20676912 |
| Guo L et al. | Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. | 2011 | Toxicol. Sci. | pmid:21693436 |
| Modali SD and Zgurskaya HI | The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. | 2011 | Mol. Microbiol. | pmid:21696464 |
| Jorgensen JH et al. | Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. | 2011 | J. Clin. Microbiol. | pmid:21697321 |
| Boghigian BA et al. | Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. | 2011 | Biotechnol. Bioeng. | pmid:21337322 |
| Kataoka M et al. | Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. | 2011 | Eur J Pharm Sci | pmid:21963456 |
| Gozalbes R et al. | QSAR-based permeability model for drug-like compounds. | 2011 | Bioorg. Med. Chem. | pmid:21458999 |
| Boleda MA et al. | Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. | 2011 | Environ. Pollut. | pmid:21459501 |
| Zhang Z et al. | Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498135 |