erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Goni BW et al. | Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. | 2014 | Trop Doct | pmid:24249028 |
Haworth CS et al. | Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. | 2014 | Respir Med | pmid:25301290 |
Zhang XF et al. | Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? | 2014 | Medicine (Baltimore) | pmid:25101987 |
Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Khannous L et al. | Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. | 2014 | Lipids Health Dis | pmid:24405763 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Belén Flórez A et al. | Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. | 2014 | Biomed Res Int | pmid:25302306 |
Kemp MW et al. | Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. | 2014 | Am. J. Obstet. Gynecol. | pmid:24589547 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Wagner G et al. | [Childhood granulomatous periorificial dermatitis]. | 2014 | Hautarzt | pmid:25115983 |
Mulatu G et al. | Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. | 2014 | Ethiop J Health Sci | pmid:24795510 |
Wu P et al. | SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24793123 |
de las Heras MN | Linear IgA bullous dermatosis of childhood: good response to antibiotic treatment. | 2014 | Clin. Exp. Dermatol. | pmid:24772486 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
Thumu SC and Halami PM | Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. | 2014 | J. Appl. Microbiol. | pmid:24206069 |
Lu B et al. | Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. | 2014 | Clin. Microbiol. Infect. | pmid:24118553 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Cuello-GarcÃa CA et al. | Treating BCG-induced disease in children. | 2013 | Cochrane Database Syst Rev | pmid:23440826 |
Jersild Jespersen M et al. | [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. | 2013 | Ugeskr. Laeg. | pmid:23462037 |
Jiang M and Pfeifer BA | Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. | 2013 | Metab. Eng. | pmid:23747605 |
Xia Q et al. | Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. | 2013 | BMC Microbiol. | pmid:23767761 |
Horácio AN et al. | The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. | 2013 | PLoS ONE | pmid:24066064 |
Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
Guo MT et al. | Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. | 2013 | Chemosphere | pmid:24055024 |
Li YY et al. | Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. | 2013 | BMC Genomics | pmid:23902230 |
Link-Gelles R et al. | Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. | 2013 | J. Infect. Dis. | pmid:23852588 |
Cai G et al. | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | 2013 | J. Nat. Prod. | pmid:24224794 |
Ong SJ et al. | Staphylococcus aureus keratitis: a review of hospital cases. | 2013 | PLoS ONE | pmid:24244625 |
Chroboczek T et al. | Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. | 2013 | PLoS ONE | pmid:24260092 |
Fang J et al. | Dissecting the function of a protruding loop in AcrB trimerization. | 2013 | J. Biomol. Struct. Dyn. | pmid:22877148 |
Opdam FL et al. | Breath tests to phenotype drug disposition in oncology. | 2013 | Clin Pharmacokinet | pmid:23868281 |
Tsujimoto M et al. | Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. | 2013 | Toxins (Basel) | pmid:23965431 |
PetráÄková D et al. | Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. | 2013 | Microbiologyopen | pmid:23996919 |
Liu ZX et al. | [Inhibition of methanogenium by erythromycin and its domestation]. | 2013 | Huan Jing Ke Xue | pmid:23798140 |
Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
Malinka W et al. | Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. | 2013 | Bioorg. Med. Chem. | pmid:23850103 |
Weber JM et al. | Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23604533 |
Goodman CD et al. | Chemobiosynthesis of new antimalarial macrolides. | 2013 | Antimicrob. Agents Chemother. | pmid:23208707 |
Li X et al. | Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. | 2013 | Eur J Med Chem | pmid:23229056 |
Nunez-Samudio V and Chesneau O | Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. | 2013 | Res. Microbiol. | pmid:23261969 |
Hisatsune J et al. | Emergence of Staphylococcus aureus carrying multiple drug resistance genes on a plasmid encoding exfoliative toxin B. | 2013 | Antimicrob. Agents Chemother. | pmid:24080652 |
Paterna A et al. | Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats. | 2013 | J. Dairy Sci. | pmid:24035026 |