erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Bronchopneumonia D001996 7 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiectasis D001987 7 associated lipids
Bradycardia D001919 13 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bone Resorption D001862 7 associated lipids
Body Weight D001835 333 associated lipids
Blister D001768 16 associated lipids
Blepharitis D001762 4 associated lipids
Bites, Human D001734 2 associated lipids
Birth Weight D001724 23 associated lipids
Bile Reflux D001655 2 associated lipids
Bartonella Infections D001474 3 associated lipids
Balanitis D001446 4 associated lipids
Bacteriuria D001437 7 associated lipids
Bacterial Infections D001424 21 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Ataxia D001259 20 associated lipids
Asthenia D001247 5 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Arthritis D001168 41 associated lipids
Spider Bites D001098 1 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Animal Diseases D000820 2 associated lipids
Angiomatosis D000798 1 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Airway Obstruction D000402 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Adenocarcinoma D000230 166 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Abscess D000038 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Zhang L et al. Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23937982
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Hirano E et al. Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. 2013 Int. J. Cardiol. pmid:22727964
Wang HB et al. Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. 2013 Biomed. Environ. Sci. pmid:24099615
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Wu C et al. Identification of elaiophylin derivatives from the marine-derived actinomycete Streptomyces sp. 7-145 using PCR-based screening. 2013 J. Nat. Prod. pmid:24164206
Arao M et al. Clostridium difficile colitis induced by long-term low-dosage erythromycin. 2013 Pediatr. Infect. Dis. J. pmid:24008746
Ziesenitz VC et al. Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms. 2013 Clin. Pharmacol. Ther. pmid:23549145
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Olender A et al. The cause of Actinomyces canalictulis--a case study. 2013 Ann Agric Environ Med pmid:24364446
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Prabu D and Menon T Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. 2013 Indian J. Med. Res. pmid:23481067
Zhang Y et al. Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23481648
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Lin MH et al. Penetration of erythromycin through Staphylococcus epidermidis biofilm. 2013 Chin. Med. J. pmid:23876889
Winnicka K et al. The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility. 2013 Molecules pmid:23881050
Kelmer G et al. Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. 2013 J. Vet. Pharmacol. Ther. pmid:23240633
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Sanger GJ et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. 2013 Br. J. Pharmacol. pmid:23189978
Rams TE et al. Antibiotic susceptibility of periodontal Enterococcus faecalis. 2013 J. Periodontol. pmid:23106507
Serisier DJ et al. Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. 2013 JAMA pmid:23532242
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215
Tarran R et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. 2013 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:23542952
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2013 Cochrane Database Syst Rev pmid:23543536
Moriya S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. 2013 Int. J. Oncol. pmid:23546223
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
Krokidis MG et al. Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. 2014 Antimicrob. Agents Chemother. pmid:24189263
Goni BW et al. Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. 2014 Trop Doct pmid:24249028
Sadeghi J and Mansouri S Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). 2014 APMIS pmid:24033803
Haworth CS et al. Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. 2014 Respir Med pmid:25301290
Nikolay R et al. Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. 2014 Nucleic Acids Res. pmid:24792169
Sanamrad A et al. Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25056965
Shim J et al. Clinical inquiry: what is the best treatment for impetigo ? 2014 J Fam Pract pmid:25061625
Krishnappa LG et al. Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. 2014 Acta Microbiol Immunol Hung pmid:24939685
Florindo C et al. Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. 2014 Euro Surveill. pmid:24957747
Ye C et al. Correlation between AcrB trimer association affinity and efflux activity. 2014 Biochemistry pmid:24854514
Zhang XF et al. Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? 2014 Medicine (Baltimore) pmid:25101987
Barbosa TM et al. A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. 2014 PLoS ONE pmid:25548909
Miyazaki M et al. [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. 2014 Yakugaku Zasshi pmid:24492229
Sugamata R et al. Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. 2014 J. Antibiot. pmid:24496145
Pasquini L et al. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. 2014 Sci. Total Environ. pmid:24631609
Fröhlicher S et al. Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. 2014 Swiss Med Wkly pmid:24652673
Cai HL et al. Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. 2014 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:24424301
Khannous L et al. Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. 2014 Lipids Health Dis pmid:24405763
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Caierão J et al. Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. 2014 PLoS ONE pmid:25356595
Arenz S et al. Drug sensing by the ribosome induces translational arrest via active site perturbation. 2014 Mol. Cell pmid:25306253
Belén Flórez A et al. Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. 2014 Biomed Res Int pmid:25302306
Farley R et al. Antibiotics for bronchiolitis in children under two years of age. 2014 Cochrane Database Syst Rev pmid:25300167
Farabella I et al. Allosteric signalling in the outer membrane translocation domain of PapC usher. 2014 Elife pmid:25271373
Wyatt TA et al. cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. 2014 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25150062
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Kemp MW et al. Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. 2014 Am. J. Obstet. Gynecol. pmid:24589547
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
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Tagawa J et al. Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. 2014 J. Microbiol. Methods pmid:25102110
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Wang Z et al. High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. 2014 Clin. Microbiol. Infect. pmid:24816168
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Mulatu G et al. Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. 2014 Ethiop J Health Sci pmid:24795510
Wu P et al. SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. 2014 J. Ind. Microbiol. Biotechnol. pmid:24793123
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Kawaguchiya M et al. Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. 2014 Microb. Drug Resist. pmid:24766085
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Boomkamp SD et al. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. 2014 Br. J. Pharmacol. pmid:24467222
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324
Brenciani A et al. Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. 2014 J. Antimicrob. Chemother. pmid:24343896
Lu WC et al. Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. 2014 Neurol. Sci. pmid:24277204
Thumu SC and Halami PM Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. 2014 J. Appl. Microbiol. pmid:24206069
Lu B et al. Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. 2014 Clin. Microbiol. Infect. pmid:24118553
Zheng PX et al. Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. 2014 Clin. Microbiol. Infect. pmid:24118239
Singh P et al. Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. 2014 Fundam Clin Pharmacol pmid:24117516
Rodríguez-Gutiérrez R et al. Herpes zoster ophthalmicus masked by hymenoptera stings. 2014 Am. J. Med. Sci. pmid:23085675