erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Pérez RA et al. | Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2017 | J Pharm Biomed Anal | pmid:28858671 |
Zankari E et al. | PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. | 2017 | J. Antimicrob. Chemother. | pmid:29091202 |
Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
Liu J et al. | Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. | 2017 | Environ. Toxicol. Pharmacol. | pmid:28802958 |
Lee JK et al. | Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine. | 2017 | J. Korean Med. Sci. | pmid:28776337 |
Jakkidi M et al. | An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction. | 2017 | BMJ Case Rep | pmid:28768672 |
Jeong S et al. | Combined photodynamic and antibiotic therapy for skin disorder via lipase-sensitive liposomes with enhanced antimicrobial performance. | 2017 | Biomaterials | pmid:28697465 |
Lamari F et al. | Assessment of the correlation among antibiotic resistance, adherence to abiotic and biotic surfaces, invasion and cytotoxicity of Pseudomonas aeruginosa isolated from diseased gilthead sea bream. | 2017 | Colloids Surf B Biointerfaces | pmid:28697438 |
Kasetty G et al. | The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection. | 2017 | Antimicrob. Agents Chemother. | pmid:28652240 |
Di Sante L et al. | pHTβ-promoted mobilization of non-conjugative resistance plasmids from Enterococcus faecium to Enterococcus faecalis. | 2017 | J. Antimicrob. Chemother. | pmid:28645197 |
Ramos CJ and Antonetti DA | The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. | 2017 | Tissue Barriers | pmid:28632993 |
Cluver C et al. | Interventions for treating genital Chlamydia trachomatis infection in pregnancy. | 2017 | Cochrane Database Syst Rev | pmid:28937705 |
Sader HS et al. | Antimicrobial Susceptibility Trends among Staphylococcus aureus Isolates from U.S. Hospitals: Results from 7 Years of the Ceftaroline (AWARE) Surveillance Program, 2010 to 2016. | 2017 | Antimicrob. Agents Chemother. | pmid:28630196 |
Tran LTC et al. | Erythromycin encapsulation in nanoemulsion-based delivery systems for treatment of Helicobacter pylori infection: Protection and synergy. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28917836 |
Post A et al. | Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:28623550 |
Tintino SR et al. | Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps. | 2017 | Bioorg. Chem. | pmid:28841421 |
Ishikawa Y et al. | Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. | 2017 | Biopharm Drug Dispos | pmid:28425104 |
Ji W et al. | Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China. | 2017 | PLoS ONE | pmid:28813477 |
Rea E and Husbands E | Erythromycin: prophylaxis against recurrent small bowel obstruction. | 2017 | BMJ Support Palliat Care | pmid:28356304 |
Wang D et al. | An analogous wood barrel theory to explain the occurrence of hormesis: A case study of sulfonamides and erythromycin on Escherichia coli growth. | 2017 | PLoS ONE | pmid:28715457 |
Hawkins PA et al. | Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. | 2017 | J. Antimicrob. Chemother. | pmid:28333320 |
Jia L et al. | Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28711353 |
Adhikari RP et al. | Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. | 2017 | BMC Infect. Dis. | pmid:28693489 |
Wang HK et al. | Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. | 2017 | BMC Infect. Dis. | pmid:28679429 |
Haynes KM et al. | Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. | 2017 | J. Med. Chem. | pmid:28650638 |
Dalal A et al. | Interventions for the prevention of recurrent erysipelas and cellulitis. | 2017 | Cochrane Database Syst Rev | pmid:28631307 |
Štšepetova J et al. | Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. | 2017 | J. Appl. Microbiol. | pmid:28574626 |
Tanaka Y et al. | Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532245 |
Demczuk WHB et al. | Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. | 2017 | PLoS ONE | pmid:28531208 |
Cheled-Shoval S et al. | From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. | 2017 | Molecules | pmid:28513558 |
Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
Lee JH et al. | Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. | 2017 | J. Microbiol. Biotechnol. | pmid:28237994 |
Calle-Miguel L et al. | [Resistance rates and phenotypic characterization of Streptococcus pyogenes in a paediatric population in Northern Spain (2005-2015)]. | 2017 | Rev Esp Quimioter | pmid:28233483 |
Selwood DL | Macrocycles, the edge of drug-likeness chemical space or Goldilocks zone? | 2017 | Chem Biol Drug Des | pmid:28205398 |
Pergola S et al. | Genetic diversity and antimicrobial resistance profiles of Campylobacter coli and Campylobacter jejuni isolated from broiler chicken in farms and at time of slaughter in central Italy. | 2017 | J. Appl. Microbiol. | pmid:28194914 |
Huang YW et al. | Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. | 2017 | Antimicrob. Agents Chemother. | pmid:28193669 |
Ge LL et al. | [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. | 2017 | Zhonghua Er Ke Za Zhi | pmid:28173648 |
Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
Liu J et al. | Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. | 2017 | Environ Sci Pollut Res Int | pmid:28004371 |
Hillitt KL et al. | Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. | 2017 | Lett. Appl. Microbiol. | pmid:27992658 |
Numanović F et al. | Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. | 2017 | Med Glas (Zenica) | pmid:27917849 |
Waites KB et al. | In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. | 2017 | Antimicrob. Agents Chemother. | pmid:27855075 |
Parthasarathy G et al. | Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial. | 2017 | J. Clin. Endocrinol. Metab. | pmid:27880079 |
Creti R et al. | Neonatal Group B Streptococcus Infections: Prevention Strategies, Clinical and Microbiologic Characteristics in 7 Years of Surveillance. | 2017 | Pediatr. Infect. Dis. J. | pmid:27870810 |
Zhang W et al. | Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. | 2017 | Mar. Pollut. Bull. | pmid:27863881 |
Li B et al. | Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. | 2017 | Foodborne Pathog. Dis. | pmid:27854542 |
Shrivastav AM et al. | Highly sensitive and selective erythromycin nanosensor employing fiber optic SPR/ERY imprinted nanostructure: Application in milk and honey. | 2017 | Biosens Bioelectron | pmid:27825873 |
Liu J et al. | Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. | 2017 | Metab. Eng. | pmid:27794466 |
Kassem II et al. | Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. | 2017 | Foodborne Pathog. Dis. | pmid:27768387 |
Lim SK et al. | Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. | 2017 | J. Vet. Med. Sci. | pmid:27593510 |
Zhou X et al. | Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. | 2017 | Mol Med Rep | pmid:28358431 |
Marlow N et al. | The ORACLE Children Study: educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. | 2017 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:27515985 |
Bitew A et al. | Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. | 2017 | BMC Infect. Dis. | pmid:28962545 |
Öksüz L and Gürler N | [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. | 2017 | Mikrobiyol Bul | pmid:28929957 |
Pan M and Chu LM | Transfer of antibiotics from wastewater or animal manure to soil and edible crops. | 2017 | Environ. Pollut. | pmid:28866424 |
Wekselman I et al. | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. | 2017 | Structure | pmid:28689968 |
Truong-Bolduc QC et al. | Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. | 2017 | Antimicrob. Agents Chemother. | pmid:28584148 |
Blackwell GA and Hall RM | The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. | 2017 | Antimicrob. Agents Chemother. | pmid:28533235 |
Dolberg AM and Reichl S | Activity of Multidrug Resistance-Associated Proteins 1-5 (MRP1-5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate. | 2017 | Mol. Pharm. | pmid:28291371 |
Massip C et al. | Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. | 2017 | J. Antimicrob. Chemother. | pmid:28137939 |
GarcÃa-Iglesias P et al. | Management of non variceal upper gastrointestinal bleeding: position statement of the Catalan Society of Gastroenterology. | 2017 | Gastroenterol Hepatol | pmid:28109636 |
Argemi X et al. | VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis. | 2017 | Clin. Microbiol. Infect. | pmid:28017792 |
Ksia S et al. | Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. | 2017 | Microb. Drug Resist. | pmid:27991848 |
Olajuyigbe OO et al. | In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. | 2017 | Acta Biochim. Pol. | pmid:28612062 |
Pfaller MA et al. | Ceftaroline Activity Against Multidrug-Resistant Streptococcus pneumoniae from U.S. Medical Centers (2014) and Molecular Characterization of a Single Ceftaroline Nonsusceptible Isolate. | 2017 | Microb. Drug Resist. | pmid:27918694 |
Chang KH et al. | Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27687157 |
Weber JM et al. | Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. | 2017 | Methods Mol. Biol. | pmid:27709581 |
Zhou Z et al. | Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. | 2017 | Front Cell Infect Microbiol | pmid:28884090 |
Peng Z et al. | Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. | 2017 | Microbiologyopen | pmid:28799224 |
Zheng PX et al. | Highly prevalent emmSTG840.0 and emmSTC839.0 types of erythromycin non-susceptible group G Streptococcus isolated from bacteremia in southern Taiwan. | 2017 | J Microbiol Immunol Infect | pmid:28711431 |
Abreu AC et al. | Looking to nature for a new concept in antimicrobial treatments: isoflavonoids from Cytisus striatus as antibiotic adjuvants against MRSA. | 2017 | Sci Rep | pmid:28630440 |
Feng L et al. | Removal of antibiotics during the anaerobic digestion of pig manure. | 2017 | Sci. Total Environ. | pmid:28628813 |
Tay JH et al. | Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. | 2017 | J. Am. Chem. Soc. | pmid:28627172 |
Hong M et al. | C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:28567527 |
Na HK et al. | Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. | 2017 | Korean J. Intern. Med. | pmid:28352063 |
Li LH et al. | [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. | 2017 | Zhonghua Yi Xue Za Zhi | pmid:28316160 |
Fohner AE et al. | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. | 2017 | Pharmacogenet. Genomics | pmid:28146011 |
Michael-Kordatou I et al. | On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. | 2017 | J. Hazard. Mater. | pmid:26947803 |
Dreno B et al. | Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. | 2017 | Exp. Dermatol. | pmid:28094874 |
Sagkan-Ozturk A et al. | Prokinetics stimulate the increase of ghrelin in mice. | 2016 | Bratisl Lek Listy | pmid:28127970 |
Aslantaş Ö and Demir C | Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. | 2016 | J. Dairy Sci. | pmid:27592437 |
Budha NR et al. | Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. | 2016 | Clin Pharmacokinet | pmid:27225997 |
Wan TW et al. | Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV. | 2016 | PLoS ONE | pmid:27741255 |
Kwon JW | Environmental impact assessment of veterinary drug on fish aquaculture for food safety. | 2016 | Drug Test Anal | pmid:27443211 |
Aslan Bayhan S et al. | Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. | 2016 | Cont Lens Anterior Eye | pmid:27422575 |
Li X et al. | Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. | 2016 | Biomed Res Int | pmid:27413745 |
Ababou A and Koronakis V | Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. | 2016 | PLoS ONE | pmid:27403665 |
Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
Sousa M et al. | Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. | 2016 | Microb. Drug Resist. | pmid:26990729 |
Morroni G et al. | Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. | 2016 | Microb. Drug Resist. | pmid:26982016 |
Lenart-Boroń A et al. | Phenotypic and Molecular Antibiotic Resistance Determination of Airborne Coagulase Negative Staphylococcus spp. Strains from Healthcare Facilities in Southern Poland. | 2016 | Microb. Drug Resist. | pmid:26978225 |
Diawara I et al. | Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. | 2016 | Infect. Genet. Evol. | pmid:26961592 |
Barros RR et al. | Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. | 2016 | J. Antimicrob. Chemother. | pmid:27029847 |
Meng HL et al. | Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis. | 2016 | Biotechnol J | pmid:26709503 |
Dréno B | Bacteriological resistance in acne: A call to action. | 2016 | Eur J Dermatol | pmid:26711531 |
Parhizgari N et al. | High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. | 2016 | APMIS | pmid:26709106 |
Li J et al. | Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. | 2016 | Nutr Clin Pract | pmid:26459161 |
Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
Feuillolay C et al. | A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris. | 2016 | Phytomedicine | pmid:26969384 |
Naik KM and Nandibewoor ST | Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. | 2016 | Luminescence | pmid:26239839 |