erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Bronchopneumonia D001996 7 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiectasis D001987 7 associated lipids
Bradycardia D001919 13 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bone Resorption D001862 7 associated lipids
Body Weight D001835 333 associated lipids
Blister D001768 16 associated lipids
Blepharitis D001762 4 associated lipids
Bites, Human D001734 2 associated lipids
Birth Weight D001724 23 associated lipids
Bile Reflux D001655 2 associated lipids
Bartonella Infections D001474 3 associated lipids
Balanitis D001446 4 associated lipids
Bacteriuria D001437 7 associated lipids
Bacterial Infections D001424 21 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Ataxia D001259 20 associated lipids
Asthenia D001247 5 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Arthritis D001168 41 associated lipids
Spider Bites D001098 1 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Animal Diseases D000820 2 associated lipids
Angiomatosis D000798 1 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Airway Obstruction D000402 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Adenocarcinoma D000230 166 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Abscess D000038 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Chen D et al. Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. 2014 PLoS ONE pmid:25250723
Blattner C et al. A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. 2014 J. Cutan. Pathol. pmid:24588271
Brenciani A et al. ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. 2014 Antimicrob. Agents Chemother. pmid:24449773
Yu ZC et al. Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. 2014 Microb. Cell Fact. pmid:24450434
Hudson BH and Zaher HS Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. 2014 Mol. Cell pmid:25514181
Pinto TC et al. Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. 2014 Braz. J. Microbiol. pmid:25477908
Katayama Y et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. 2014 Brain Res. pmid:25264351
Bauer CA and Grimme S First principles calculation of electron ionization mass spectra for selected organic drug molecules. 2014 Org. Biomol. Chem. pmid:25260171
Kinouchi H et al. Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. 2014 Biol. Pharm. Bull. pmid:25087959
Bos JC et al. Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. 2014 BMC Res Notes pmid:24568650
Feng Y et al. Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. 2014 Foodborne Pathog. Dis. pmid:25054781
Sahu AK et al. Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. 2014 Biomed Res Int pmid:25045692
Nilsson MF and Webster WS Effects of macrolide antibiotics on rat embryonic heart function in vitro. 2014 Birth Defects Res. B Dev. Reprod. Toxicol. pmid:24753334
Murphree CA et al. Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. 2014 Curr. Microbiol. pmid:24748439
Sakamoto N et al. Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. 2014 Intern. Med. pmid:24739609
Szemraj M et al. Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. 2014 Microb. Drug Resist. pmid:24735183
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. 2014 J. Fish Dis. pmid:23992037
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
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Utsunomiya S et al. Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. 2013 Regul. Pept. pmid:23142315
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Parrott N et al. An unusual cause of persistent postpartum vaginal discharge. 2013 Int J STD AIDS pmid:23970614
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Gold RM and Lawhon SD Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. 2013 J. Clin. Microbiol. pmid:24025915
Henson AM et al. Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. 2013 J. Clin. Microbiol. pmid:24048538
Wieczorek K et al. Prevalence and antimicrobial resistance of Campylobacter spp. isolated from poultry carcasses in Poland. 2013 J. Food Prot. pmid:23905805
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). 2013 J. Fish Dis. pmid:24118016
Sripriya J et al. Laser receptive polyelectrolyte thin films doped with biosynthesized silver nanoparticles for antibacterial coatings and drug delivery applications. 2013 Int J Pharm pmid:24096301
Wang HB et al. Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. 2013 Biomed. Environ. Sci. pmid:24099615
Avci O et al. A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. 2013 J Dermatolog Treat pmid:21923567
Pohl O et al. Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. 2013 J Clin Pharm Ther pmid:24102384
Kelley C et al. Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. 2013 Eur J Med Chem pmid:23314053
González-Pleiter M et al. Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. 2013 Water Res. pmid:23399078
Odhav A et al. Subconjunctival latex paint from occupational injury. 2013 J Emerg Med pmid:23399395
Ziesenitz VC et al. Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms. 2013 Clin. Pharmacol. Ther. pmid:23549145
Magee TV et al. Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. 2013 Bioorg. Med. Chem. Lett. pmid:23414806
Lermite E et al. Complications after pancreatic resection: diagnosis, prevention and management. 2013 Clin Res Hepatol Gastroenterol pmid:23415988
Atamanyuk D et al. Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. 2013 J. Med. Chem. pmid:23445125
Gomes DL et al. SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. 2013 J. Med. Microbiol. pmid:23449875
Yang M et al. Macrolides for diffuse panbronchiolitis. 2013 Cochrane Database Syst Rev pmid:23450579
Schafer F et al. Antimicrobial susceptibility and genetic characteristics of Propionibacterium acnes isolated from patients with acne. 2013 Int. J. Dermatol. pmid:23432195
Chen Y et al. Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. 2013 Bioresour. Technol. pmid:23500575
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Basak R and Bandyopadhyay R Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. 2013 Langmuir pmid:23472840
Broad J and Sanger GJ The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. 2013 Br. J. Pharmacol. pmid:23190027
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Yang J et al. Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. 2013 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:23474502
Zhang Q et al. High-resolution melting analysis for the detection of two erythromycin-resistant Bordetella pertussis strains carried by healthy schoolchildren in China. 2013 Clin. Microbiol. Infect. pmid:23480481
Prabu D and Menon T Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. 2013 Indian J. Med. Res. pmid:23481067
Capanna F et al. Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. 2013 Swiss Med Wkly pmid:23572445
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Chen Y et al. Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. 2013 Bioprocess Biosyst Eng pmid:23361182
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Gaudreau C et al. Campylobacter coli outbreak in men who have sex with men, Quebec, Canada, 2010-2011. 2013 Emerging Infect. Dis. pmid:23647786
Kjær S et al. Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. 2013 Dan Med J pmid:23651712
Ragazzi E et al. Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. 2013 J Chemother pmid:23684362
Rasamiravaka T et al. Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. 2013 J Infect Dev Ctries pmid:23592641
Nakajima T et al. Absence of intervening sequences and point mutations in the V domain within 23S rRNA in Campylobacter lari isolates. 2013 Folia Microbiol. (Praha) pmid:23595231
Ma X et al. Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children. 2013 Chin. Med. J. pmid:23595388
Hinarejos P et al. The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. 2013 J Bone Joint Surg Am pmid:23636182
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Pelchovich G et al. Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene. 2013 Int. J. Antimicrob. Agents pmid:23664678
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Jiang M et al. The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. 2013 J Vis Exp pmid:23354010
Elens L et al. CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. 2013 Pharmacogenomics pmid:23327575
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Rożynek E et al. Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. 2013 Foodborne Pathog. Dis. pmid:23638847
Grabowicz M et al. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. 2013 J. Bacteriol. pmid:23316047
Dubey D et al. A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. 2013 Asian Pac J Trop Biomed pmid:23593595
Marcellin E et al. Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. 2013 BMC Genomics pmid:23324121
Romeiro FG et al. Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study. 2013 BMC Gastroenterol pmid:23324408
Elens L et al. Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin. 2013 Pharmacogenet. Genomics pmid:23324807
Boutouyrie-Dumont B An aide memoire for model-based drug development--a new key for the interpretation of the erythromycin breath test--therapeutic index as a biomarker for smart drug development. 2013 Biomark Med pmid:23387489
Cui B et al. Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. 2013 J. Clin. Microbiol. pmid:23052315
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Serisier DJ et al. Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. 2013 JAMA pmid:23532242
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247