erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). II. Characterization of CFS patients with special reference to their response to a new vitamin C infusion treatment. | 1996 Nov-Dec | In Vivo | pmid:8986468 |
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). I. A Pilot study of the new vitamin C infusion treatment with a volunteer CFS patient. | 1996 Nov-Dec | In Vivo | pmid:8986467 |
Shortridge VD et al. | Novel mechanism of macrolide resistance in Streptococcus pneumoniae. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8985659 |
Ono T et al. | In vitro and in vivo antibacterial activities of clarithromycin. | 1996 May-Jun | Chemotherapy | pmid:8983882 |
Sasaki J et al. | Microbial glycosylation of macrolide antibiotics by Streptomyces hygroscopicus ATCC 31080 and distribution of a macrolide glycosyl transferase in several Streptomyces strains. | 1996 | J. Antibiot. | pmid:8982340 |
Brenciaglia MI et al. | Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. | 1996 | J Chemother | pmid:8981182 |
Vermeij CG et al. | Campylobacter jejuni peritonitis in a patient with liver cirrhosis. | 1996 | Eur J Gastroenterol Hepatol | pmid:8980944 |
Fasola EL et al. | Variation in erythromycin and clindamycin susceptibilities of Streptococcus pneumoniae by four test methods. | 1997 | Antimicrob. Agents Chemother. | pmid:8980768 |
Watkins VS et al. | Comparison of dirithromycin and penicillin for treatment of streptococcal pharyngitis. | 1997 | Antimicrob. Agents Chemother. | pmid:8980757 |
Neri I et al. | Perianal streptococcal dermatitis in adults. | 1996 | Br. J. Dermatol. | pmid:8977685 |
Brugiere O et al. | Diffuse panbronchiolitis in an Asian immigrant. | 1996 | Thorax | pmid:8977613 |
Adachi T et al. | Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. | 1996 | J. Allergy Clin. Immunol. | pmid:8977529 |
Moriyasu H et al. | [Erythromycin-induced hearing loss in a patient with Listeria monocytogenes meningo-ventriculitis]. | 1996 | Rinsho Shinkeigaku | pmid:8976138 |
Mashimoto H et al. | [Acute bronchiolitis due to Mycoplasma pneumoniae and successfully treated with steroids]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8976087 |
Kakkos SK et al. | Gallbladder contraction induced by intravenous erythromycin administration. Relation to body mass index. | 1996 Nov-Dec | Hepatogastroenterology | pmid:8975963 |
van't Hullenaar NG et al. | Relapse of Legionella longbeachae infection in an immunocompromised patient. | 1996 | Neth J Med | pmid:8973096 |
Clancy J et al. | Molecular cloning and functional analysis of a novel macrolide-resistance determinant, mefA, from Streptococcus pyogenes. | 1996 | Mol. Microbiol. | pmid:8971709 |
Jenkins IR and Gibson J | Cisapride, erythromycin and arrhythmia. | 1996 | Anaesth Intensive Care | pmid:8971331 |
Landry C et al. | Could oral erythromycin optimize high energy continuous enteral nutrition? | 1996 | Aliment. Pharmacol. Ther. | pmid:8971296 |
Jorro G et al. | Anaphylaxis to erythromycin. | 1996 | Ann. Allergy Asthma Immunol. | pmid:8970433 |
Kaufman D | Treating acute bronchitis. | 1996 | J Fam Pract | pmid:8969687 |
Kimber RG | Treating acute bronchitis. | 1996 | J Fam Pract | pmid:8969686 |
Lazarevski G et al. | Ring opening reactions of 6-deoxy-9-deoxo-9a-aza-9a-homoerythromycin A 6,9-cyclic imino ether. | 1996 | J. Antibiot. | pmid:8968405 |
Grandjean C and Lukacs G | Preparation and in vitro antibacterial activity of 9-O-glycosyloxime derivatives of erythromycin A, a new class of macrolide antibiotics. | 1996 | J. Antibiot. | pmid:8968398 |
Rahal JJ and Simberkoff MS | Cases 1, 2, and 3. | 1977 | Postgrad Med | pmid:896609 |
Antzelevitch C et al. | Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsade de pointes. | 1996 | J. Am. Coll. Cardiol. | pmid:8962574 |
Lagergård T et al. | Comparison of the Etest with agar dilution for antimicrobial susceptibility testing of Haemophilus ducreyi. | 1996 | J. Antimicrob. Chemother. | pmid:8961054 |
Yamazaki H et al. | Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes. | 1996 | J Toxicol Sci | pmid:8959645 |
Wynn RL | New erythromycins. | 1996 Jul-Aug | Gen Dent | pmid:8957824 |
Liu C | Best ways to handle upper respiratory infections. | 1977 | Med Times | pmid:895439 |
Prevention of bacterial endocarditis. | 1977 | Med Times | pmid:895437 | |
Suwabe A et al. | [Effects of erythromycin on surfactant synthesis, secretion, and recycling by rat alveolar type II cells]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8953904 |
Roos K et al. | Recolonization with selected alpha-streptococci for prophylaxis of recurrent streptococcal pharyngotonsillitis--a randomized placebo-controlled multicentre study. | 1996 | Scand. J. Infect. Dis. | pmid:8953674 |
Durak H et al. | Lung clearance of inhaled 99Tcm-erythromycin lactobionate in non-smokers and smokers. | 1996 | Nucl Med Commun | pmid:8951912 |
Kalliafas S et al. | Erythromycin facilitates postpyloric placement of nasoduodenal feeding tubes in intensive care unit patients: randomized, double-blinded, placebo-controlled trial. | 1996 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:8950737 |
Mittermayer H et al. | Antibiotic susceptibility of pneumococci isolated in Austria over a four-year period. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8950561 |
Fass RJ et al. | The utility of non-beta-lactam antimicrobial MICs as markers to distinguish oxacillin-resistant from oxacillin-susceptible strains of Staphylococcus epidermidis. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8950529 |
Ringger NC et al. | Effect of bethanechol or erythromycin on gastric emptying in horses. | 1996 | Am. J. Vet. Res. | pmid:8950433 |
Regnery RL et al. | Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. | 1996 | Am. J. Vet. Res. | pmid:8950424 |
Media Villa Garcia JD et al. | [Acute pancreatitis secondary to intravenous administration of erythromycin]. | 1996 | An Med Interna | pmid:8948830 |
Yamazaki H et al. | Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes. | 1996 | Xenobiotica | pmid:8948090 |
Evans G et al. | Pertussis. | 1996 | CMAJ | pmid:8943933 |
Hotta M | Neutrophil chemotactic activity in cryptogenic organizing pneumonia and the response to erythromycin. | 1996 | Kurume Med J | pmid:8942140 |
Kernbaum SK and Blayo MC | Lack of influence of antibiotic therapy on concentrations of glucose and inorganic elements in saliva. | 1977 | J. Infect. Dis. | pmid:894084 |
Dagan R et al. | Nasopharyngeal colonization in southern Israel with antibiotic-resistant pneumococci during the first 2 years of life: relation to serotypes likely to be included in pneumococcal conjugate vaccines. | 1996 | J. Infect. Dis. | pmid:8940233 |
Jones RN et al. | Clindamycin resistance among erythromycin-resistant Streptococcus pneumoniae. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8937845 |
Brisaert M et al. | Investigation on the chemical stability of erythromycin in solutions using an optimization system. | 1996 | Pharm World Sci | pmid:8933579 |
Raimondo F et al. | Unusual isoxazoline formation by intramolecular cyclization of (9E)-erythromycin A oxime. | 1996 | J. Antibiot. | pmid:8931730 |
Fomina IP et al. | [Azithromycin (sumamed)--in the treatment of respiratory tract infections]. | 1996 | Antibiot. Khimioter. | pmid:8929121 |
Toreson H and Eriksson BM | Determination of erythromycin in gastric juice and blood plasma by liquid chromatography and electrochemical detection. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:8925078 |
Schmidt HU et al. | Isolation of Bartonella quintana from an HIV-positive patient with bacillary angiomatosis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8922574 |
Horn JW et al. | In vitro and in vivo ultrastructural changes induced by macrolide antibiotic LY281389. | 1996 | Fundam Appl Toxicol | pmid:8921323 |
Carlson AM and Morris LS | Coprescription of terfenadine and erythromycin or ketaconazole: an assessment of potential harm. | 1996 | J Am Pharm Assoc (Wash) | pmid:8919602 |
Bowles KM et al. | A 35-year-old with swollen knees who had recurrent fever and pericarditis, then diarrhoea before getting better. | 1996 | Lancet | pmid:8918280 |
Kleinman B | Should antibiotics be prophylactically administered to a patient with an asymptomatic systolic murmur? | 1996 | Anesthesiology | pmid:8916856 |
Vowels BR et al. | Effects of topical erythromycin on ecology of aerobic cutaneous bacterial flora. | 1996 | Antimicrob. Agents Chemother. | pmid:8913472 |
Sutcliffe J et al. | Detection of erythromycin-resistant determinants by PCR. | 1996 | Antimicrob. Agents Chemother. | pmid:8913465 |
Hayakawa H et al. | Bronchiolar disease in rheumatoid arthritis. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8912776 |
Nakagawa M et al. | Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis. | 1996 | J. Neurovirol. | pmid:8912211 |
Appelbaum PC et al. | Carriage of antibiotic-resistant Streptococcus pneumoniae by children in eastern and central Europe--a multicenter study with use of standardized methods. | 1996 | Clin. Infect. Dis. | pmid:8909832 |
Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |
Yasui N | [The relationship between single-oral dose kinetics of alprazolam and cytochrome P4503A and cytochrome P4502C19]. | 1996 | Nihon Shinkei Seishin Yakurigaku Zasshi | pmid:8905799 |
Mosca A et al. | Evaluation of the efficacy of josamycin in the treatment of impetigo in children and its in vitro activity on erythromycin resistant Staphylococcus aureus strains. | 1995 | J Chemother | pmid:8904141 |
Perez-Ramos S et al. | Incidence of erythromycin resistance and penicillin resistance in clinical isolates of Streptococcus pneumoniae from a Spanish university hospital. | 1995 | J Chemother | pmid:8904113 |
Ohtomo T et al. | Effect of sub-inhibitory concentrations of clarithromycin and erythromycin on the production of Staphylococcus aureus capsules. | 1995 | J Chemother | pmid:8904089 |
Kimani J et al. | Low dose erythromycin regimen for the treatment of chancroid. | 1995 | East Afr Med J | pmid:8904044 |
Wheeley MS | Erythromycin in renal failure. | 1977 | Br Med J | pmid:890394 |
Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
Guerrero-Lindner E et al. | Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. | 1996 | Peptides | pmid:8899807 |
Okano H et al. | EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. | 1996 | Peptides | pmid:8899806 |
Yau TH and Butrus SI | Presumed bilateral herpes zoster ophthalmicus in an AIDS patient: a case report. | 1996 | Cornea | pmid:8899277 |
Jayaraman SC et al. | Topical delivery of erythromycin from various formulations: an in vivo hairless mouse study. | 1996 | J Pharm Sci | pmid:8897275 |
Jorgensen JH et al. | Development of interpretive criteria and quality control limits for macrolide and clindamycin susceptibility testing of Streptococcus pneumoniae. | 1996 | J. Clin. Microbiol. | pmid:8897164 |
Wadowsky RM et al. | Multiplex PCR-based assay for detection of Bordetella pertussis in nasopharyngeal swab specimens. | 1996 | J. Clin. Microbiol. | pmid:8897157 |
Nay TS | Extra-pulmonary Rhodococcus equi in a thoroughbred foal. | 1996 | Can. Vet. J. | pmid:8896881 |
Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
Matschiner S et al. | Influence of ion pairing on ex vivo penetration of erythromycin into sebaceous follicles. | 1996 | Skin Pharmacol. | pmid:8896118 |
Ross JD et al. | Efficacy of anti-chlamydial therapy with oxytetracycline and erythromycin. | 1996 Aug-Sep | Int J STD AIDS | pmid:8894832 |
Shinagawa S et al. | Exacerbation of tracheobronchitis due to nontoxigenic Corynebacterium diphtheriae. | 1996 | Intern. Med. | pmid:8894741 |
Clarke JS et al. | Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. | 1977 | Ann. Surg. | pmid:889372 |
Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
Hunt Gerardo S et al. | Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8891154 |
Tateda K et al. | Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891128 |
Benson JM et al. | Tonsillar tissue penetration of dirithromycin after multiple doses. | 1996 | J Clin Pharmacol | pmid:8889904 |
Biedenbach D et al. | Comparative in-vitro activity of quinupristin/dalfopristin (RP 59500) tested against penicillin-and macrolide-resistant pneumococci by the Etest. | 1996 | J. Antimicrob. Chemother. | pmid:8889731 |
Viluksela M et al. | Cytotoxicity of macrolide antibiotics in a cultured human liver cell line. | 1996 | J. Antimicrob. Chemother. | pmid:8889721 |
Davies P et al. | Erythromycin resistance of Campylobacter isolates from pigs. | 1996 | Vet. Rec. | pmid:8883355 |
Valsecchi R et al. | Contact allergy to erythromycin. | 1996 | Contact Derm. | pmid:8879932 |
Alcaide F et al. | In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878591 |
Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
Amin AS and Issa YM | Selective spectrophotometric method for the determination of erythromycin and its esters in pharmaceutical formulations using gentiana violet. | 1996 | J Pharm Biomed Anal | pmid:8877871 |
Uwaydah M et al. | Antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Lebanon. | 1996 | J. Antimicrob. Chemother. | pmid:8877543 |
Kürekçi AE et al. | The frequency of resistance to erythromycin in group A streptococci in Ankara. | 1996 | Eur. J. Pediatr. | pmid:8874111 |
Gómez J et al. | Prospective study of epidemiology and prognostic factors in community-acquired pneumonia. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8874072 |
Jones DR et al. | Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. | 1996 | Clin. Pharmacol. Ther. | pmid:8873685 |
Ridgway GL and Oriel JD | Treatment of neonatal inclusion blennorrhea. | 1977 | N. Engl. J. Med. | pmid:887138 |
Sato M et al. | [Erythromycin derivative EM574 with motilin agonistic effect on human gastric antrum]. | 1995 | J Smooth Muscle Res | pmid:8867985 |
Shiba Y et al. | [Mechanism of increased gastric motility effect of EM523]. | 1995 | J Smooth Muscle Res | pmid:8867984 |
Toyota K et al. | A study of pyloric function after pylorus-preserving pancreatoduodenectomy in the canine model. | 1995 | J Smooth Muscle Res | pmid:8867940 |