erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Baltch AL et al. | Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila. | 2000 | J. Antimicrob. Chemother. | pmid:10882688 |
Chiba T et al. | Motilides accelerate regional gastrointestinal transit in the dog. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886053 |
Cocuzza G | The microbiological characteristics of troleandomycin. | 1975 | Quad Antibiot | pmid:1088736 |
Barrett-Connor E | Current status of the treatment of syphilis. | 1975 | West. J. Med. | pmid:1089007 |
Järvinen T et al. | [Prodrugs]. | 1997 | Duodecim | pmid:10892164 |
Schmitz FJ et al. | Distribution of macrolide-resistance genes in Staphylococcus aureus blood-culture isolates from fifteen German university hospitals. M.A.R.S. Study Group. Multicentre Study on Antibiotic Resistance in Staphylococci. | 2000 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10898143 |
Tait-Kamradt A et al. | Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage. | 2000 | Antimicrob. Agents Chemother. | pmid:10898684 |
Wehbeh H et al. | Erythromycin for chlamydiasis in pregnant women. Assessing adherence to a standard multiday, multidose course. | 2000 | J Reprod Med | pmid:10900579 |
van Erpecum KJ et al. | Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. | 2000 | Aliment. Pharmacol. Ther. | pmid:10903008 |
Adderson E et al. | A community pseudo-outbreak of invasive Staphylococcus aureus infection. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:10904197 |
Stratton-Phelps M et al. | Risk of adverse effects in pneumonic foals treated with erythromycin versus other antibiotics: 143 cases (1986-1996). | 2000 | J. Am. Vet. Med. Assoc. | pmid:10909450 |
Zueva VS et al. | [Dynamics of the antibiotic sensitivity of the staphylococci in suppurative, inflammatory foci in patients during the period of the hospital stay]. | 1975 | Antibiotiki | pmid:1091206 |
Lacey RW | Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance. | 1975 | Bacteriol Rev | pmid:1091256 |
Lin FY et al. | Antibiotic susceptibility profiles for group B streptococci isolated from neonates, 1995-1998. | 2000 | Clin. Infect. Dis. | pmid:10913400 |
Kobayashi Y et al. | Development of a competitive polymerase chain reaction assay for the ruminal bacterium Butyrivibrio fibrisolvens OB156 and its use for tracking an OB156-derived recombinant. | 2000 | FEMS Microbiol. Lett. | pmid:10913703 |
Rudolph KM et al. | Serotype distribution and antimicrobial resistance patterns of invasive isolates of Streptococcus pneumoniae: Alaska, 1991-1998. | 2000 | J. Infect. Dis. | pmid:10915080 |
Zhang Y et al. | Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. | 2000 | RNA | pmid:10917591 |
Yost NP et al. | An appraisal of treatment guidelines for antepartum community-acquired pneumonia. | 2000 | Am. J. Obstet. Gynecol. | pmid:10920320 |
Joshi A et al. | Palmar erythema nodosum. | 2000 | J. Dermatol. | pmid:10920594 |
Chapman MJ et al. | Erythromycin improves gastric emptying in critically ill patients intolerant of nasogastric feeding. | 2000 | Crit. Care Med. | pmid:10921561 |
Zaloga GP and Marik P | Promotility agents in the intensive care unit. | 2000 | Crit. Care Med. | pmid:10921616 |
Lin HC et al. | Erythromycin inhibits beta2-integrins (CD11b/CD18) expression, interleukin-8 release and intracellular oxidative metabolism in neutrophils. | 2000 | Respir Med | pmid:10926336 |
Hammerschlag MR | Treatment of Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10926449 |
Hashemi K et al. | Comparison of antibiotic drops placed in the conjunctival cul-de-sac to antibiotic ointment applied to the lid margin in reduction of bacterial colonization on the lid margin. | 2000 | Cornea | pmid:10928757 |
Dreassi E et al. | High-performance liquid chromatographic assay of erythromycin from biological matrix using electrochemical or ultraviolet detection. | 2000 | Analyst | pmid:10932853 |
Eady EA et al. | Antibiotic resistance patterns of aerobic coryneforms and furazolidone-resistant Gram-positive cocci from the skin surface of the human axilla and fourth toe cleft. | 2000 | J. Antimicrob. Chemother. | pmid:10933642 |
Schultz MJ et al. | Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10933646 |
Wasilewski MM et al. | Comparative efficacy of 5 days of dirithromycin and 7 days of erythromycin in skin and soft tissue infections. | 2000 | J. Antimicrob. Chemother. | pmid:10933649 |
Leaf T et al. | Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: understanding precursor effects. | 2000 Jul-Aug | Biotechnol. Prog. | pmid:10933827 |
Slain D et al. | Variability in activity of hepatic CYP3A4 in patients infected with HIV. | 2000 | Pharmacotherapy | pmid:10939550 |
Burkhart CN et al. | Synergistic activity of benzoyl peroxide and erythromycin. | 2000 Sep-Oct | Skin Pharmacol. Appl. Skin Physiol. | pmid:10940820 |
De Soyza A et al. | An unusual case of pulmonary abscess. | 2000 | J. Infect. | pmid:10942653 |
Wardrop J et al. | Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography. | 2000 | J Pharm Sci | pmid:10944374 |
Johnston WS | Eradication of STR agalactiae from infected herds using erythromycin. | 1975 | Vet. Rec. | pmid:1094673 |
Lozniewski A et al. | Comparison of the in vitro activity of pristinamycin and quinupristin/dalfopristin against Streptococcus pneumoniae. | 2000 | Pathol. Biol. | pmid:10949841 |
Lakritz J et al. | Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals. | 2000 | Am. J. Vet. Res. | pmid:10951982 |
Masuda N et al. | Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa. | 2000 | Antimicrob. Agents Chemother. | pmid:10952562 |
Pendland SL et al. | In vitro activities of a new ketolide, ABT-773, alone and in combination with amoxicillin, metronidazole, or tetracycline against Helicobacter pylori. | 2000 | Antimicrob. Agents Chemother. | pmid:10952605 |
Goldstein EJ et al. | Comparative in vitro activities of ABT-773 against aerobic and anaerobic pathogens isolated from skin and soft-tissue animal and human bite wound infections. | 2000 | Antimicrob. Agents Chemother. | pmid:10952607 |
Bebear CM et al. | In vitro activity of trovafloxacin compared to those of five antimicrobials against mycoplasmas including Mycoplasma hominis and Ureaplasma urealyticum fluoroquinolone-resistant isolates that have been genetically characterized. | 2000 | Antimicrob. Agents Chemother. | pmid:10952617 |
Durieu-Trautmann O and Tavlitzki J | Reversible and permanent effects of the carbon sources and various antibiotics on the morphology and metabolic properties of Ustilago cynodontis cells. | 1975 | J. Cell Biol. | pmid:1095594 |
Xiang H et al. | An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates. | 2000 | J. Biol. Chem. | pmid:10956654 |
Mobley DF | Semen cultures in the diagnosis of bacterial prostatitis. | 1975 | J. Urol. | pmid:1095783 |
Williams DA | Stevens-Johnson syndrome after erythromycin therapy while deployed at sea. | 2000 | Mil Med | pmid:10957862 |
Hatipoglu ON and Tasan Y | A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. | 2000 | Yonsei Med. J. | pmid:10957888 |
Heude M and Chanet R | Protein synthesis and the recovery of both survival and cytoplasmic "petite" mutation in ultraviolet-treated yeast cells. II. Mitochondrial protein synthesis. | 1975 | Mutat. Res. | pmid:1095920 |
O'Grady FW et al. | Sensible prescribing. III. Acute otitis media and sore throat. | 1975 | Practitioner | pmid:1096124 |
Palmer NA et al. | A study of prophylactic antibiotic prescribing in National Health Service general dental practice in England. | 2000 | Br Dent J | pmid:10967824 |
Camardella L et al. | Nuclear and cytoplasmic glutamate dehydrogenases (NADP-dependent) in Saccharomyces cerevisiae. | 1975 | Biochem. Biophys. Res. Commun. | pmid:1096883 |
Barbacid M et al. | The mode of action of griseoviridin at the ribosome level. | 1975 | Biochim. Biophys. Acta | pmid:1096949 |