erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
Watanabe I et al. | Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. | 2011 | Int Heart J | pmid:22188715 |
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Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
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Khan NW et al. | Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. | 2011 | Pak J Pharm Sci | pmid:21190914 |
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Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
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Hoa PT et al. | Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. | 2011 | Sci. Total Environ. | pmid:21669325 |
Maragno AL et al. | ISG15 modulates development of the erythroid lineage. | 2011 | PLoS ONE | pmid:22022510 |
Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
Kreft A et al. | JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. | 2011 | Virchows Arch. | pmid:22006129 |
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Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
Loreto ES et al. | In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. | 2011 | Antimicrob. Agents Chemother. | pmid:21537028 |
Nakamura PA et al. | Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. | 2011 | Mem. Inst. Oswaldo Cruz | pmid:21537668 |
Shaala LA et al. | Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. | 2011 | J. Nat. Prod. | pmid:21542602 |
Zhao DL et al. | Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. | 2011 | Microb. Cell Fact. | pmid:21542941 |
Gannon M et al. | Clinical inquiries. Which oral antibiotics are best for acne? | 2011 | J Fam Pract | pmid:21544278 |
Chia HY et al. | Follicular spicules associated with Propionibacterium acnes in response to erythromycin. | 2011 | J. Dermatol. | pmid:21544949 |
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Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |
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Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Abdel Fattah NS and Darwish YW | Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. | 2012 | Int. J. Dermatol. | pmid:22928620 |
Kjeldgaard J et al. | Residual antibiotics disrupt meat fermentation and increase risk of infection. | 2012 | MBio | pmid:22930338 |
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Li SL et al. | A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. | 2012 | Chin. Med. J. | pmid:22931973 |
Waśko A et al. | Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. | 2012 | J. Antibiot. | pmid:22948255 |
Counsell H | An abdominal mass in a 4-year-old child. | 2012 | BMJ Case Rep | pmid:22922923 |
Juntunen P et al. | Campylobacter coli isolates from Finnish farrowing farms using aminopenicillins: high prevalence of bla(OXA-61) and β-lactamase production, but low MIC values. | 2012 | Foodborne Pathog. Dis. | pmid:22924522 |
Kwiatkowska B and Maślińska M | Macrolide therapy in chronic inflammatory diseases. | 2012 | Mediators Inflamm. | pmid:22969171 |
Leyden JJ | In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory. | 2012 | J Drugs Dermatol | pmid:23377513 |
Hess TM and Chew HF | Successful treatment of acute ocular involvement in Stevens-Johnson syndrome with amniotic membrane transplantation: a case report. | 2012 | Can. J. Ophthalmol. | pmid:23217513 |
Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
Fazeli M et al. | Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. | 2012 | J. Vet. Pharmacol. Ther. | pmid:22066489 |
Reutenauer-Patte J et al. | Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. | 2012 | Am. J. Pathol. | pmid:22192627 |
Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
Luangtongkum T et al. | Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. | 2012 | Antimicrob. Agents Chemother. | pmid:22183170 |
Soeters HM et al. | Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. | 2012 | Antimicrob. Agents Chemother. | pmid:22232291 |
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Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Janssen BD et al. | Analysis of aminoacyl- and peptidyl-tRNAs by gel electrophoresis. | 2012 | Methods Mol. Biol. | pmid:22736012 |
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Harvey CJ et al. | Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. | 2012 | J. Am. Chem. Soc. | pmid:22741553 |
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Gokmen T et al. | A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities. | 2012 | J Perinatol | pmid:21566568 |
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Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
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Imai Y et al. | Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance. | 2012 | J. Antibiot. | pmid:22491137 |
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Vendrell D et al. | Accumulation and depletion kinetics of erythromycin in rainbow trout (Oncorhynchus mykiss). | 2012 | Prev. Vet. Med. | pmid:22436556 |
Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
Peano C et al. | Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. | 2012 | Microb. Cell Fact. | pmid:22401291 |
Chen CM | Erythromycin for the treatment of feeding intolerance in preterm infants. | 2012 | Pediatr Neonatol | pmid:22348487 |
Ng YY et al. | Efficacy of intermediate-dose oral erythromycin on very low birth weight infants with feeding intolerance. | 2012 | Pediatr Neonatol | pmid:22348492 |
Yoon SB et al. | The effect of exenatide and erythromycin on postprandial symptoms and their relation to gastric functions. | 2012 | Digestion | pmid:22354133 |
Golparian D et al. | In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea? | 2012 | Antimicrob. Agents Chemother. | pmid:22354296 |
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Giovanetti E et al. | ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. | 2012 | Antimicrob. Agents Chemother. | pmid:21986826 |
Cannon JA et al. | Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. | 2012 | Dis. Colon Rectum | pmid:23044677 |
Kaul M et al. | A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. | 2012 | J. Med. Chem. | pmid:23050700 |
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Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. | 2012 | Antimicrob. Agents Chemother. | pmid:23027190 |
PiÄ…tkowska E et al. | The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells. | 2012 | Cell. Mol. Biol. Lett. | pmid:23001512 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
Brill S et al. | Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23035252 |
Kou X et al. | Synthesis, characterization and adsorption behavior of molecularly imprinted nanospheres for erythromycin using precipitation polymerization. | 2012 | J Nanosci Nanotechnol | pmid:23035481 |