erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kumpfmüller J et al. | Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26432460 |
Deloose E et al. | Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. | 2016 | Gut | pmid:25986945 |
Talebi M et al. | Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. | 2016 | PLoS ONE | pmid:28033345 |
Krishnamoorthy G et al. | Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. | 2016 | Antimicrob. Agents Chemother. | pmid:27697764 |
Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
Murchison L et al. | Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. | 2016 | Pediatr. Surg. Int. | pmid:27655365 |
Dzyubak E and Yap MN | The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. | 2016 | Antimicrob. Agents Chemother. | pmid:27645242 |
Karlsson E et al. | Clonality of erythromycin resistance in Francisella tularensis. | 2016 | J. Antimicrob. Chemother. | pmid:27334667 |
Changchien CH et al. | Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. | 2016 | BMC Infect. Dis. | pmid:27287530 |
Waiser MJ et al. | Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. | 2016 | Ecotoxicol. Environ. Saf. | pmid:27261880 |
KarniÄar K et al. | Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. | 2016 | Microb. Cell Fact. | pmid:27255285 |
Ghosh S and Banerjee M | Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. | 2016 | Indian J. Med. Res. | pmid:27241651 |
Pignatello R et al. | Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. | 2016 | Eur J Med Chem | pmid:27236014 |
Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
Sierra-Arguello YM et al. | Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. | 2016 | Avian Pathol. | pmid:26925976 |
Molina-Manso D et al. | Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. | 2016 | J. Antibiot. | pmid:26905757 |
Madmanang S et al. | Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. | 2016 | J. Nat. Prod. | pmid:26905094 |
Aydin S et al. | Assessment of anaerobic bacterial diversity and its effects on anaerobic system stability and the occurrence of antibiotic resistance genes. | 2016 | Bioresour. Technol. | pmid:26897411 |
Baek YS et al. | Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. | 2016 | Int. J. Dermatol. | pmid:26892888 |
Jin Y et al. | From the Cover: Exposure to Oral Antibiotics Induces Gut Microbiota Dysbiosis Associated with Lipid Metabolism Dysfunction and Low-Grade Inflammation in Mice. | 2016 | Toxicol. Sci. | pmid:27503388 |
Chua SL et al. | Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. | 2016 | Nat Commun | pmid:26892159 |
Chuang MC et al. | Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. | 2016 | J. Formos. Med. Assoc. | pmid:26705139 |
Broad J et al. | RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions. | 2016 | J. Pharmacol. Sci. | pmid:26685754 |
Sayed Ahmed WA et al. | Maternal serum interleukin-6 in the management of patients with preterm premature rupture of membranes. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26669630 |
Vitali LA et al. | Correlation between genetic features of the mef(A)-msr(D) locus and erythromycin resistance in Streptococcus pyogenes. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:26429294 |
Sugawara A et al. | Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model. | 2016 | J. Antibiot. | pmid:26419414 |
Brunel R and Charpentier X | Trans-translation is essential in the human pathogen Legionella pneumophila. | 2016 | Sci Rep | pmid:27892503 |
Dayie NT et al. | Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. | 2015 | Microb. Drug Resist. | pmid:26172078 |
He M et al. | Dynamics of serotype 14 Streptococcus pneumoniae population causing acute respiratory infections among children in China (1997-2012). | 2015 | BMC Infect. Dis. | pmid:26163293 |
Piccinelli G et al. | Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. | 2015 | Infect. Genet. Evol. | pmid:26144658 |
Wang P et al. | Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. | 2015 | Int. J. Infect. Dis. | pmid:26141418 |
Melkumyan AR et al. | Effects of antibiotic treatment on the lactobacillus composition of vaginal microbiota. | 2015 | Bull. Exp. Biol. Med. | pmid:25894774 |
Romaniszyn D et al. | Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. | 2015 | BMC Infect. Dis. | pmid:25888217 |
Park JY et al. | Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. | 2015 | Plasmid | pmid:25882072 |
Jakubů V et al. | Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. | 2015 | Epidemiol Mikrobiol Imunol | pmid:25872990 |
Koutsogiannidis CP et al. | Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. | 2015 | J Card Surg | pmid:25858150 |
Xu CW et al. | First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. | 2015 | Antimicrob. Agents Chemother. | pmid:25666150 |
Naquin A et al. | Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. | 2015 | Bioresour. Technol. | pmid:25662190 |
GarcÃa-Mayor MA et al. | Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. | 2015 | Food Chem. Toxicol. | pmid:25637760 |
Chan BC et al. | Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. | 2015 | J. Pharm. Pharmacol. | pmid:25212982 |
Shishkina AV et al. | Modeling Interactions of Erythromycin Derivatives with Ribosomes. | 2015 | Biochemistry Mosc. | pmid:26615442 |
Li X et al. | Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. | 2015 | Sci Rep | pmid:26607739 |
Cheng C et al. | Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. | 2015 | Pathol. Res. Pract. | pmid:26601615 |
Yang Y et al. | Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014). | 2015 | PLoS ONE | pmid:26406905 |
O'Connor SE | Engineering of Secondary Metabolism. | 2015 | Annu. Rev. Genet. | pmid:26393965 |
Borges V et al. | Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. | 2015 | Appl. Environ. Microbiol. | pmid:26386065 |
Dixit S and Park JH | Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. | 2015 | J Chromatogr A | pmid:26372443 |
Michael-Kordatou I et al. | Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. | 2015 | Water Res. | pmid:26360228 |
Ozbayram EG et al. | Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. | 2015 | Environ Sci Pollut Res Int | pmid:25408075 |
Aydın S et al. | The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. | 2015 | Water Sci. Technol. | pmid:25909721 |