erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wirsing von König CH et al. | Factors influencing the analysis of secondary prevention of pertussis. | 1997 | Dev. Biol. Stand. | pmid:9272349 |
Schaller U et al. | [Ophthalmia neonatorum caused by Chlamydia trachomatis. Rapid diagnosis and therapy]. | 1997 | Ophthalmologe | pmid:9273028 |
Anderson KL | Genetic manipulation of anaerobic cellulolytic bacteria. | 1997 | SAAS Bull. Biochem. Biotechnol. | pmid:9274059 |
Hu H et al. | A case of diffuse panbronchiolitis. | 1996 | Chin. Med. J. | pmid:9275329 |
Wang X et al. | [Effects of changes of plasma motilin level on the motility of gallbladder in patients with chronic renal failure]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9275623 |
Pemberton M et al. | Treating oral candidiasis: potentially fatal. | 1997 | Br Dent J | pmid:9282448 |
Nishijima S and Nakagawa M | Sensitivity of antibacterials of Staphylococcus aureus isolated from impetigo patients. | 1997 Jul-Aug | J. Int. Med. Res. | pmid:9283995 |
Miyata Y et al. | Porphyromonas gingivalis lipopolysaccharide-stimulated bone resorption via CD14 is inhibited by broad-spectrum antibiotics. | 1997 | Infect. Immun. | pmid:9284114 |
Jadcherla SR et al. | Regulation of migrating motor complexes by motilin and pancreatic polypeptide in human infants. | 1997 | Pediatr. Res. | pmid:9284278 |
Vassallo M and Shepherd RJ | A case of relapsing psittacosis associated with a stroke. | 1997 | Int. J. Clin. Pract. | pmid:9287275 |
Alkhawajah AM | Studies on the antimicrobial activity of juglans regia. | 1997 | Am. J. Chin. Med. | pmid:9288364 |
Aldighieri S et al. | [The status of antibiotic sensitivity of Vibrio cholerae 0:1 in Ecuador]. | 1997 | Med Trop (Mars) | pmid:9289622 |
Bradley AJ and Green MJ | Clinical mastitis in dairy cows after 'blitz' therapy. | 1997 | Vet. Rec. | pmid:9290201 |
Rovira A et al. | Acute colonic pseudo-obstruction (Ogilvie's syndrome) treated with erythromycin. | 1997 | Intensive Care Med | pmid:9291000 |
Martin MV et al. | Acute dentoalveolar infections: an investigation of the duration of antibiotic therapy. | 1997 | Br Dent J | pmid:9293130 |
Visalli MA et al. | Susceptibility of twenty penicillin-susceptible and -resistant pneumococci to levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin by MIC and time-kill. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9294703 |
Czambor-Ksiazek E et al. | [Disorders of gastric emptying in diabetes. II. Treatment]. | 1997 | Wiad. Lek. | pmid:9297356 |
Cohen MA and Huband MD | In-vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum to clinafloxacin, PD 131628, ciprofloxacin and comparator drugs. | 1997 | J. Antimicrob. Chemother. | pmid:9302005 |
Visalli MA et al. | Susceptibility of penicillin-susceptible and -resistant pneumococci to dirithromycin compared with susceptibilities to erythromycin, azithromycin, clarithromycin, roxithromycin, and clindamycin. | 1997 | Antimicrob. Agents Chemother. | pmid:9303375 |
Ednie LM et al. | Comparative antianaerobic activities of the ketolides HMR 3647 (RU 66647) and HMR 3004 (RU 64004). | 1997 | Antimicrob. Agents Chemother. | pmid:9303406 |
Roblin PM et al. | In vitro activity of trovafloxacin against Chlamydia pneumoniae. | 1997 | Antimicrob. Agents Chemother. | pmid:9303410 |
Mercer BM et al. | Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. A randomized controlled trial. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. | 1997 | JAMA | pmid:9307346 |
Berman S et al. | Otitis media-related antibiotic prescribing patterns, outcomes, and expenditures in a pediatric medicaid population. | 1997 | Pediatrics | pmid:9310510 |
Hegde R | Gastric emptying and prokinetics. | 1997 | Intensive Care Med | pmid:9310822 |
Wilmer A et al. | Gastric emptying in the critically ill--the way forward. | 1997 | Intensive Care Med | pmid:9310823 |
Katapadi K et al. | A review of erythromycin-induced malignant tachyarrhythmia--torsade de pointes. A case report. | 1997 | Angiology | pmid:9313632 |
Blackman HJ et al. | Antibiotic susceptibility of Chlamydia trachomatis. | 1977 | Antimicrob. Agents Chemother. | pmid:931365 |
Newell AM et al. | Nephrotic syndrome associated with bacillary angiomatosis in a patient with AIDS. | 1997 | Clin. Infect. Dis. | pmid:9314482 |
Ju J and Goo YM | 8-Deoxylankolide from a lankamycin producing Streptomyces spp. | 1997 | J. Antibiot. | pmid:9315083 |
Nichols RL et al. | Preoperative bowel preparation. Erythromycin base serum and fecal levels following oral administration. | 1977 | Arch Surg | pmid:931637 |
Kopp VJ et al. | Intravenous erythromycin promotes gastric emptying prior to emergency anesthesia. | 1997 | Anesthesiology | pmid:9316982 |
Martin JR et al. | 3'-de-o-methyl-2', 3'-anhydro-lankamycin, a new macrolide antibiotic from Streptomyces violaceoniger. | 1976 | Helv. Chim. Acta | pmid:931757 |
George RH and Bint AJ | Letter: Treatment of a brain abscess due to Bacteroides fragilis with metronidazole. | 1976 | J. Antimicrob. Chemother. | pmid:931828 |
Easterbrook SM and Hersey JA | Bioautography of erythromycin and its esters. | 1976 | J. Chromatogr. | pmid:932154 |
Ballard RC et al. | Delayed hypersensitivity to Chlamydia trachomatis: cause of chronic prostatitis. | 1979 | Lancet | pmid:93221 |
Májský A and Chudomel V | Inactivation of HL-A antigens in vitro by action of antibiotics. | 1976 | J. Immunogenet. | pmid:932464 |
Kundu S et al. | Clarithromycin-induced ventricular tachycardia. | 1997 | Ann Emerg Med | pmid:9326871 |
Yang YH et al. | Opacity factor inhibition test for typing group A beta-haemolytic streptococcus strains and antibiotic susceptibility. | 1997 | Adv. Exp. Med. Biol. | pmid:9331595 |
Jasir A and Schalén C | Erythromycin resistance phenotypes in Swedish clinical isolates of group A streptococci. | 1997 | Adv. Exp. Med. Biol. | pmid:9331689 |
Savoia D et al. | Group A streptococci. Erythromycin resistance and penicillin tolerance. | 1997 | Adv. Exp. Med. Biol. | pmid:9331690 |
Vicarini H et al. | Analysis of regulatory region of ermAM genes in streptococci and enterococci highly resistant to macrolides and lincosamides. | 1997 | Adv. Exp. Med. Biol. | pmid:9331702 |
Syrogiannopoulos GA et al. | Resistance patterns of streptococcus pneumoniae from carriers attending day-care centers in southwestern Greece. | 1997 | Clin. Infect. Dis. | pmid:9332508 |
Tait-Kamradt A et al. | mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae. | 1997 | Antimicrob. Agents Chemother. | pmid:9333056 |
Kivistö KT et al. | Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole. | 1997 | Clin. Pharmacol. Ther. | pmid:9333111 |
Ruan X et al. | Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives. | 1997 | J. Bacteriol. | pmid:9335291 |
Taylor D | Pharmacokinetic interactions involving clozapine. | 1997 | Br J Psychiatry | pmid:9337943 |
Borzani M et al. | A survey of susceptibility to erythromycin amongst Streptococcus pyogenes isolates in Italy. | 1997 | J. Antimicrob. Chemother. | pmid:9338507 |
Mitsuyama T et al. | Neutrophil-induced endothelial cell damage: inhibition by a 14-membered ring macrolide through the action of nitric oxide. | 1997 | Int. Arch. Allergy Immunol. | pmid:9338603 |
Nalepa P et al. | [Chlamydia pneumoniae as an etiologic agent in severe pneumonias]. | 1997 | Pneumonol Alergol Pol | pmid:9340067 |
Lookingbill DP et al. | Treatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigations. | 1997 | J. Am. Acad. Dermatol. | pmid:9344199 |