erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Faoagali JL et al. Sensitivity of 941 beta haemolytic streptococci to antibacterial drugs. 1976 N. Z. Med. J. pmid:1070586
Karam B et al. Ergotism precipitated by erythromycin: a rare case of vasospasm. 2000 Eur J Vasc Endovasc Surg pmid:10706847
Sazykin IuO et al. [Ketolides--erythromycin derivatives with activity against macrolide-resistant bacteria]. 2000 Antibiot. Khimioter. pmid:10707799
MacLaren R et al. Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: a randomized, placebo-controlled, crossover study. 2000 Crit. Care Med. pmid:10708180
Krecic-Shepard ME et al. Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans. 2000 J Clin Pharmacol pmid:10709150
Moussa F et al. Erythromycin eye ointment: effect on gastrointestinal motility. 2000 Am. J. Gastroenterol. pmid:10710093
Dewan NA et al. Acute exacerbation of COPD: factors associated with poor treatment outcome. 2000 Chest pmid:10712989
López de Blanc S et al. Bacillary angiomatosis affecting the oral cavity. Report of two cases and review. 2000 J. Oral Pathol. Med. pmid:10718405
Chepkwony HK et al. Separation of erythromycin and related substances on base-deactivated reversed-phase silica gel columns. 2000 J Chromatogr A pmid:10722081
Portillo A et al. Macrolide resistance genes in Enterococcus spp. 2000 Antimicrob. Agents Chemother. pmid:10722498
Brophy DF et al. Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers. 2000 Antimicrob. Agents Chemother. pmid:10722500
Ono T et al. Susceptibilities of oral and nasal isolates of Streptococcus mitis and Streptococcus oralis to macrolides and PCR detection of resistance genes. 2000 Antimicrob. Agents Chemother. pmid:10722517
Strigl S et al. In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae. 2000 Antimicrob. Agents Chemother. pmid:10722526
Gracey HE et al. Preparation and in vitro antibacterial activity of 6-O-methylerythromycin D. 1999 J. Antibiot. pmid:10726932
Smith AJ et al. Prokinetic effect of erythromycin after colorectal surgery: randomized, placebo-controlled, double-blind study. 2000 Dis. Colon Rectum pmid:10733114
Karchmer AW et al. Single-antibiotic therapy for streptococcal endocarditis. 1979 JAMA pmid:107335
Potts JM et al. Association of chronic urinary symptoms in women and Ureaplasma urealyticum. 2000 Urology pmid:10736488
Dubini F et al. [Research on erythromycin and spiramycin in saliva]. 1976 Dent Cadmos pmid:1073735
Or YS et al. Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. 2000 J. Med. Chem. pmid:10737737
Orrett FA Methicillin resistance among Trinidadian isolates of community and hospital strains of Staphylococcus aureus and their patterns of resistance to non-beta-lactam antibiotics. 1999 Jpn. J. Infect. Dis. pmid:10738361