erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Reinert RR et al. In vitro activities of the new ketolide antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany. 1998 Antimicrob. Agents Chemother. pmid:9624505
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Stassi DL et al. Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9636144
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Shimatani T Involvement of cholinergic motor neurons in pharmacological regulation of gastrointestinal motility by glucagon in conscious dogs. 1997 Aug-Oct J Smooth Muscle Res pmid:9639019
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Gharaibeh MN et al. Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers. 1998 J Clin Pharmacol pmid:9650537
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Orden B et al. Erythromycin resistance of Streptococcus pyogenes in Madrid. 1998 Pediatr. Infect. Dis. J. pmid:9655536
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D'Souza P et al. A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. 1998 Sex Transm Dis pmid:9662762
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Griffin RG Dipolar recoupling in MAS spectra of biological solids. 1998 Nat. Struct. Biol. pmid:9665180
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Hayakawa H et al. Diffuse panbronchiolitis and rheumatoid arthritis-associated bronchiolar disease: similarities and differences. 1998 Intern. Med. pmid:9678682
Enomoto F et al. [Evaluation of methods of macrolide antibiotic administration in experimental otitis media of rats]. 1997 Jpn J Antibiot pmid:9678980
Ikeda K et al. [Effect of macrolide antibiotics on ion transport of nasal mucosal epithelium]. 1997 Jpn J Antibiot pmid:9678982
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Stassi D et al. A genetically engineered strain of Saccharopolyspora erythraea that produces 6,12-dideoxyerythromycin A as the major fermentation product. 1998 Appl. Microbiol. Biotechnol. pmid:9684306
Tripathi S et al. Ketolide resistance conferred by short peptides. 1998 J. Biol. Chem. pmid:9685347
Bowman ED et al. Impact of erythromycin on respiratory colonization of Ureaplasma urealyticum and the development of chronic lung disease in extremely low birth weight infants. 1998 Pediatr. Infect. Dis. J. pmid:9686728
Hamilton-Miller JM and Shah S Comparative in-vitro activity of ketolide HMR 3647 and four macrolides against gram-positive cocci of known erythromycin susceptibility status. 1998 J. Antimicrob. Chemother. pmid:9687104
Gaudreau C and Gilbert H Antimicrobial resistance of clinical strains of Campylobacter jejuni subsp. jejuni isolated from 1985 to 1997 in Quebec, Canada. 1998 Antimicrob. Agents Chemother. pmid:9687415
Petrakis J et al. Enhancement of gastric emptying of solids by erythromycin in patients with Roux-en-Y gastrojejunostomy. 1998 Arch Surg pmid:9687997
Ehrenpreis ED et al. Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. 1998 Aliment. Pharmacol. Ther. pmid:9690728
Staunton J Combinatorial biosynthesis of erythromycin and complex polyketides. 1998 Curr Opin Chem Biol pmid:9691072
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Weissman KJ et al. Origin of starter units for erythromycin biosynthesis. 1998 Biochemistry pmid:9692995
Milla E et al. Bilateral optic papillitis following mycoplasma pneumoniae pneumonia. 1998 Ophthalmologica pmid:9693295