erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sadeghi J and Mansouri S | Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). | 2014 | APMIS | pmid:24033803 |
Luminos M et al. | Nasopharyngeal carriage of Streptococcus pneumoniae in Romanian children before the introduction of the pneumococcal conjugated vaccination into the national immunization programme: a national, multi-centre, cross-sectional observational study. | 2014 | Int. J. Infect. Dis. | pmid:25461243 |
Silva CM et al. | Population dynamics and antimicrobial susceptibility of Aeromonas spp. along a salinity gradient in an urban estuary in Northeastern Brazil. | 2014 | Mar. Pollut. Bull. | pmid:25455376 |
Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
Leirós M et al. | Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. | 2014 | ACS Chem Neurosci | pmid:24219236 |
Westerhof J et al. | Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. | 2014 | BMC Gastroenterol | pmid:25234278 |
Badri T et al. | [Erythrasma: study of 16 cases]. | 2014 | Tunis Med | pmid:25224418 |
Dörries K et al. | Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. | 2014 | Antimicrob. Agents Chemother. | pmid:25224006 |
Zhang Y et al. | [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721407 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
Iatrou EI et al. | Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24981036 |
Ramos V et al. | [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. | 2014 | Biomedica | pmid:24968052 |
Xu J et al. | Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. | 2014 | J. Food Sci. | pmid:24689704 |
Wang D et al. | Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. | 2014 | Microb. Drug Resist. | pmid:24684286 |
Arenz S et al. | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. | 2014 | Nat Commun | pmid:24662426 |
Fernández Fuentes MA et al. | Synergistic activity of biocides and antibiotics on resistant bacteria from organically produced foods. | 2014 | Microb. Drug Resist. | pmid:24660956 |
RodrÃguez-Gutiérrez R et al. | Herpes zoster ophthalmicus masked by hymenoptera stings. | 2014 | Am. J. Med. Sci. | pmid:23085675 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Jiang M and Pfeifer BA | Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. | 2013 | Metab. Eng. | pmid:23747605 |
Xia Q et al. | Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. | 2013 | BMC Microbiol. | pmid:23767761 |
Guan Y et al. | [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23724685 |
Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
Guo MT et al. | Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. | 2013 | Chemosphere | pmid:24055024 |
Link-Gelles R et al. | Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. | 2013 | J. Infect. Dis. | pmid:23852588 |
Ong SJ et al. | Staphylococcus aureus keratitis: a review of hospital cases. | 2013 | PLoS ONE | pmid:24244625 |
Chroboczek T et al. | Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. | 2013 | PLoS ONE | pmid:24260092 |
Novy P et al. | Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. | 2013 | Phytomedicine | pmid:23485046 |
Panditi VR et al. | Online solid-phase extraction-liquid chromatography-electrospray-tandem mass spectrometry determination of multiple classes of antibiotics in environmental and treated waters. | 2013 | Anal Bioanal Chem | pmid:23494277 |
Tsujimoto M et al. | Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. | 2013 | Toxins (Basel) | pmid:23965431 |
PetráÄková D et al. | Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. | 2013 | Microbiologyopen | pmid:23996919 |
Katipoglu-Yazan T et al. | Acute impact of erythromycin and tetracycline on the kinetics of nitrification and organic carbon removal in mixed microbial culture. | 2013 | Bioresour. Technol. | pmid:23892149 |
Liu JF et al. | [Effect of erythromycin on electrical activity and gastric emptying of the intrathoracic stomach after esophagectomy for esophageal cancer]. | 2013 | Zhonghua Wei Chang Wai Ke Za Zhi | pmid:24061999 |
Broad J and Sanger GJ | The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. | 2013 | Br. J. Pharmacol. | pmid:23190027 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
Malinka W et al. | Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. | 2013 | Bioorg. Med. Chem. | pmid:23850103 |
Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
Weber JM et al. | Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23604533 |
Yang X et al. | Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. | 2013 | Environ Sci Pollut Res Int | pmid:23608973 |
Ferrieri P et al. | Serotype IV and invasive group B Streptococcus disease in neonates, Minnesota, USA, 2000-2010. | 2013 | Emerging Infect. Dis. | pmid:23628320 |
Li X et al. | Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. | 2013 | Eur J Med Chem | pmid:23229056 |
Nunez-Samudio V and Chesneau O | Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. | 2013 | Res. Microbiol. | pmid:23261969 |
Secka O et al. | Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. | 2013 | Antimicrob. Agents Chemother. | pmid:23263004 |
Bruchmann J et al. | Sub-inhibitory concentrations of antibiotics and wastewater influencing biofilm formation and gene expression of multi-resistant Pseudomonas aeruginosa wastewater isolates. | 2013 | Environ Sci Pollut Res Int | pmid:23392972 |