erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Choroiditis D002833 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Sialadenitis D012793 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Microphthalmos D008850 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Epidural Abscess D020802 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Angiomatosis D000798 1 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Myiasis D009198 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Ehrlichiosis D016873 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Onychomycosis D014009 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Gardner Syndrome D005736 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Rubella D012409 2 associated lipids
Seroma D049291 2 associated lipids
Bile Reflux D001655 2 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Furunculosis D005667 2 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hypoventilation D007040 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Fathollahipour S et al. Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. 2015 J Biomed Mater Res A pmid:26112829
Xing L et al. ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. 2015 PLoS ONE pmid:26107936
Dridi B et al. Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. 2015 Antimicrob. Agents Chemother. pmid:26100702
Czarnetzki C et al. Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. 2015 JAMA Surg pmid:26083537
Patti MG Erythromycin Use Before Induction of General Endotracheal Anesthesia. 2015 JAMA Surg pmid:26083012
Haenen CC et al. [Rosacea fulminans in pregnancy]. 2015 Ned Tijdschr Geneeskd pmid:26058762
Chew ML et al. Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. 2015 Clin Drug Investig pmid:25808394
Ericson JE et al. Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. 2015 J. Pediatr. Gastroenterol. Nutr. pmid:25806675
Aydin S et al. Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. 2015 Water Res. pmid:25792437
Zhu Y et al. Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". 2015 Sci Rep pmid:25791905
Wang P et al. Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. 2015 PLoS ONE pmid:25781346
Zhou Y et al. Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. 2015 Talanta pmid:25770599
Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Johnson AC et al. Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. 2015 Sci. Total Environ. pmid:25617699
Wang P et al. Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. 2015 Microb. Cell Fact. pmid:25612661
Chiaverini C et al. Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. 2015 Br. J. Dermatol. pmid:25601422
Li Z et al. New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. 2015 Lett. Appl. Microbiol. pmid:25588530
Gardiner SJ et al. Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. 2015 Cochrane Database Syst Rev pmid:25566754
Azadegan A et al. Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. 2015 Ann Lab Med pmid:25553281
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Wang Z et al. Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. 2015 Food Chem pmid:25308648
Hawkins PA et al. Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. 2015 Microb. Drug Resist. pmid:25115711
Vallianou N et al. Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. 2015 J Chemother pmid:25112954
Kempe H et al. Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. 2015 Pharm. Res. pmid:25103333
Yang J et al. Improving heterologous polyketide production in Escherichia coli by transporter engineering. 2015 Appl. Microbiol. Biotechnol. pmid:26062534
Muralidharan V and Striepen B Teaching old drugs new tricks to stop malaria invasion in its tracks. 2015 BMC Biol. pmid:26349580
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Feng T et al. Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. 2015 J. Comput. Aided Mol. Des. pmid:26564143
Daghighi S et al. Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. 2015 Int. J. Antimicrob. Agents pmid:26526893
Bravo-Rodriguez K et al. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. 2015 Chem. Biol. pmid:26526102
Wróblewska M and Winnicka K The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. 2015 Int J Mol Sci pmid:26343637
Bolukaoto JY et al. Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. 2015 BMC Res Notes pmid:26289147
Liao CH et al. DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. 2015 Appl. Microbiol. Biotechnol. pmid:26272095
Thomas L et al. Ophthalmic Considerations in Stevens-Johnson Syndrome. 2016 J. Pediatr. pmid:27318376
Tang C et al. The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. 2016 Sci Rep pmid:27897206
Sun H et al. Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. 2016 Sci Rep pmid:27644411
Tack J et al. Motilin-induced gastric contractions signal hunger in man. 2016 Gut pmid:25539673
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
Caumes E et al. [Donovanosis (granuloma inguinale)]. 2016 Ann Dermatol Venereol pmid:27773509
Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Ben Salem I et al. Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. 2016 Curr. Microbiol. pmid:27447798
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Baker KR et al. A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. 2016 Antimicrob. Agents Chemother. pmid:27458225
Juda M et al. The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. 2016 Mem. Inst. Oswaldo Cruz pmid:27008373
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
Bhadra PK et al. Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. 2016 Org. Biomol. Chem. pmid:27273525
Topp E et al. Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. 2016 Sci. Total Environ. pmid:27096634
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753
Snoeys J et al. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Clin. Pharmacol. Ther. pmid:26259716