erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Takada T et al. | [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. | 1997 | Jpn J Antibiot | pmid:9597465 |
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| Tei A et al. | [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. | 1997 | Jpn J Antibiot | pmid:9597458 |
| Kudo S | [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. | 1997 | Jpn J Antibiot | pmid:9597457 |
| Kondo K et al. | [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597456 |
| Kobayashi O et al. | [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597455 |
| Ohara K et al. | [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597454 |
| Sato K et al. | [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. | 1997 | Jpn J Antibiot | pmid:9597453 |
| Mineshita M et al. | [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597447 |
| Kawasaki S et al. | [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597446 |
| Suzuki H et al. | [Il-8 secretion by cultured epithelial cells of human nasal mucosa and its suppression by macrolide antibiotics]. | 1997 | Jpn J Antibiot | pmid:9597442 |
| Nakada J et al. | [Effects of erythromycin and roxithromycin on airway goblet cell secretion]. | 1997 | Jpn J Antibiot | pmid:9597441 |
| Ieshiro R et al. | [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer]. | 1997 | Jpn J Antibiot | pmid:9597440 |
| Sakata K et al. | [Effects of macrolide antibiotics to inhibit infiltration and proliferation of malignant tumor cells--in vitro evaluation]. | 1997 | Jpn J Antibiot | pmid:9597435 |
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| Dodhia H and Miller E | Review of the evidence for the use of erythromycin in the management of persons exposed to pertussis. | 1998 | Epidemiol. Infect. | pmid:9593483 |
| Spangler SK et al. | Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9593160 |
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| Malizia T et al. | Synergic interactions of macrolides and proton-pump inhibitors against Helicobacter pylori: a comparative in-vitro study. | 1998 | J. Antimicrob. Chemother. | pmid:9579710 |
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| Hoppe JE | Susceptibility testing of Bordetella pertussis. | 1998 | J. Clin. Microbiol. | pmid:9574735 |
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| Andrews PA | Interactions with ciprofloxacin and erythromycin leading to aminophylline toxicity. | 1998 | Nephrol. Dial. Transplant. | pmid:9568870 |
| Riley RJ and Howbrook D | In vitro analysis of the activity of the major human hepatic CYP enzyme (CYP3A4) using [N-methyl-14C]-erythromycin. | 1997 | J Pharmacol Toxicol Methods | pmid:9566442 |
| Delgado LF et al. | Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9564984 |
| Jamkhedkar PP et al. | Clinico-epidemiologic features of granuloma inguinale in the era of acquired immune deficiency syndrome. | 1998 | Sex Transm Dis | pmid:9564722 |
| Salah-Bey K et al. | Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea. | 1998 | Mol. Gen. Genet. | pmid:9563840 |
| Kieran E et al. | Group B streptococcus (GBS) colonisation among expectant Irish mothers. | 1998 Jan-Feb | Ir Med J | pmid:9563251 |
| Mitsuyama T et al. | Release of nitric oxide and expression of constitutive nitric oxide synthase of human endothelial cells: enhancement by a 14-membered ring macrolide. | 1998 | Mol. Cell. Biochem. | pmid:9562252 |
| Garcia-Bermejo I et al. | Emergence of erythromycin-resistant, clindamycin-susceptible Streptococcus pyogenes isolates in Madrid, Spain. | 1998 | Antimicrob. Agents Chemother. | pmid:9559831 |
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| Roblin PM and Hammerschlag MR | In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9559818 |
| Barry AL et al. | Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin). | 1998 | Antimicrob. Agents Chemother. | pmid:9559816 |
| Rutman A et al. | Effect of dirithromycin on Haemophilus influenzae infection of the respiratory mucosa. | 1998 | Antimicrob. Agents Chemother. | pmid:9559781 |
| Cleary RK et al. | Metronidazole may inhibit intestinal colonization with Clostridium difficile. | 1998 | Dis. Colon Rectum | pmid:9559631 |
| Ross JI et al. | Resistance to erythromycin and clindamycin in cutaneous propionibacteria is associated with mutations in 23S rRNA. | 1998 | Dermatology (Basel) | pmid:9557230 |
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