erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Moutard I et al. | In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. | 1999 Sep-Oct | Therapie | pmid:10667098 |
Mordi MN et al. | Acid-catalyzed degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy. | 2000 | J. Med. Chem. | pmid:10669574 |
Munroe CO and Lazarus TL | Prevention of infective endocarditis. | 1976 | Dent J | pmid:1067255 |
Gibson J et al. | Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease. | 2000 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:10673652 |
Holen S | Antibiotics used traditionally in periodontal therapy. | 1976 | J. Periodontol. | pmid:1067412 |
Biddle JW and Thornsberry C | In vitro activity of rosamicin, josamycin, erythromycin, and clindamycin against beta-lactamase-nagative and beta-lactamase-positive strains of Neisseria gonorrhoeae. | 1979 | Antimicrob. Agents Chemother. | pmid:106776 |
Kohri K et al. | Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages. | 2000 | Eur. Respir. J. | pmid:10678622 |
Poyart C et al. | Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child. | 2000 | Antimicrob. Agents Chemother. | pmid:10681362 |
Tang X and Cheng D | [The value of erythromycin pleurodesis in the treatment of malignant pleural effusions]. | 1997 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:10683963 |
Berg TG et al. | Ureaplasma/Mycoplasma-infected amniotic fluid: pregnancy outcome in treated and nontreated patients. | 1999 | J Perinatol | pmid:10685238 |
Fail PA et al. | Comparative effects of quinacrine and erythromycin in adult female rats: a nonsurgical sterilization study. | 2000 | Fertil. Steril. | pmid:10685548 |
Yamano K et al. | Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688631 |
Noerr B | Erythromycin. | 1999 | Neonatal Netw | pmid:10690102 |
Thwaites RT and Frost JA | Drug resistance in Campylobacter jejuni, C coli, and C lari isolated from humans in north west England and Wales, 1997. | 1999 | J. Clin. Pathol. | pmid:10690169 |
Vardy SJ and Rose GE | Prevention of cellulitis after open lacrimal surgery: a prospective study of three methods. | 2000 | Ophthalmology | pmid:10690832 |
Hill BC et al. | A simplified method for testing Bordetella pertussis for resistance to erythromycin and other antimicrobial agents. | 2000 | J. Clin. Microbiol. | pmid:10699011 |
Timosca S et al. | [Bacteremia following tooth extractions]. | 1976 | Rev Stomatol Chir Maxillofac | pmid:1070098 |
Suri A et al. | Effects of CYP3A inhibition on the metabolism of cilostazol. | 1999 | Clin Pharmacokinet | pmid:10702888 |
Bernabéu JA et al. | Microbiological bioassay of erythromycin thiocyanate: optimisation and validation. | 1999 | J Pharm Biomed Anal | pmid:10703990 |
Brisaert M et al. | Investigation of the chemical stability of an erythromycin-tretinoin lotion by the use of an optimization system. | 2000 | Int J Pharm | pmid:10704802 |